{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T15:32:01Z","timestamp":1789140721797,"version":"build-2803163510"},"reference-count":53,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T00:00:00Z","timestamp":1634688000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Management of end-stage renal disease (ESRD) patients requires monitoring each of the components of malnutrition\u2013inflammation\u2013atherosclerosis (MIA) syndrome. Restrictive diet can negatively affect nutritional status and inflammation. An acute-phase protein\u2014\u03b11-acid glycoprotein (AGP), has been associated with energy metabolism in animal and human studies. The aim of our study was to look for a relationship between serum AGP concentrations, laboratory parameters, and nutrient intake in ESRD patients. The study included 59 patients treated with maintenance hemodialysis. A 24 h recall assessed dietary intake during four non-consecutive days\u2014two days in the post-summer period, and two post-winter. Selected laboratory tests were performed: complete blood count, serum iron, total iron biding capacity (TIBC) and unsaturated iron biding capacity (UIBC), vitamin D, AGP, C-reactive protein (CRP), albumin, prealbumin, and phosphate\u2013calcium metabolism markers (intact parathyroid hormone, calcium, phosphate). Recorded dietary intake was highly deficient. A majority of patients did not meet recommended daily requirements for energy, protein, fiber, iron, magnesium, folate, and vitamin D. AGP correlated positively with CRP (R = 0.66), platelets (R = 0.29), and negatively with iron (R = \u22120.27) and TIBC (R = \u22120.30). AGP correlated negatively with the dietary intake of plant protein (R = \u22120.40), potassium (R = \u22120.27), copper (R = \u22120.30), vitamin B6 (R = \u22120.27), and folates (R = \u22120.27), p &lt; 0.05. However, in multiple regression adjusted for confounders, only CRP was significantly associated with AGP. Our results indicate that in hemodialyzed patients, serum AGP is weakly associated with dietary intake of several nutrients, including plant protein.<\/jats:p>","DOI":"10.3390\/nu13113671","type":"journal-article","created":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T21:31:26Z","timestamp":1634765486000},"page":"3671","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["\u03b11-Acid Glycoprotein and Dietary Intake in End-Stage Renal Disease Patients"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8190-2481","authenticated-orcid":false,"given":"Ma\u0142gorzata","family":"Maraj","sequence":"first","affiliation":[{"name":"Department of Physiology, Faculty of Medicine, Jagiellonian University Medical College, Grzeg\u00f3rzecka 16 St., 31-531 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulina","family":"Hetwer","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Dietetics, Jagiellonian University Medical College, Anny 12 St., 31-008 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beata","family":"Ku\u015bnierz-Cabala","sequence":"additional","affiliation":[{"name":"Chair of Clinical Biochemistry, Department of Diagnostics, Faculty of Medicine, Jagiellonian University Medical College, Skawi\u0144ska 8 St., 31-066 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Maziarz","sequence":"additional","affiliation":[{"name":"Chair of Clinical Biochemistry, Department of Diagnostics, Faculty of Medicine, Jagiellonian University Medical College, Skawi\u0144ska 8 St., 31-066 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3667-857X","authenticated-orcid":false,"given":"Paulina","family":"Dumnicka","sequence":"additional","affiliation":[{"name":"Department of Medical Diagnostics, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Ku\u017aniewski","sequence":"additional","affiliation":[{"name":"Chair and Department of Nephrology, Faculty of Medicine, Jagiellonian University Medical College, Jakubowskiego 2 St., 30-688 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3478-0108","authenticated-orcid":false,"given":"Piotr","family":"Ceranowicz","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine, Jagiellonian University Medical College, Grzeg\u00f3rzecka 16 St., 31-531 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,10,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"k5301","DOI":"10.1136\/bmj.k5301","article-title":"Adiposity and risk of decline in glomerular filtration rate: Meta-analysis of individual participant data in a global consortium on behalf of the CKD Prognosis Consortium (CKD-PC)","volume":"364","author":"Chang","year":"2019","journal-title":"BMJ"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1097\/MNH.0000000000000212","article-title":"The dual roles of obesity in chronic kidney disease: A review of the current literature","volume":"25","author":"Ahmadi","year":"2016","journal-title":"Curr. 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