{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T02:55:35Z","timestamp":1780887335537,"version":"3.54.1"},"reference-count":39,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2021,11,2]],"date-time":"2021-11-02T00:00:00Z","timestamp":1635811200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Research Foundation (NRF) of Korea","award":["NRF-2018-R1D1A1A02085328 and 2021-R1C1C100498611"],"award-info":[{"award-number":["NRF-2018-R1D1A1A02085328 and 2021-R1C1C100498611"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Although the effects of coffee consumption and physical exercise on the risk of cancer have been suggested, their interactions have not been investigated. The present cross-sectional study aimed to investigate the correlation of coffee consumption and physical exercise with cancer. Participants \u226540 years old in the Korean Genome and Epidemiology Study 2004\u20132016 were included (n = 162,220). Histories of gastric cancer, hepatic cancer, colon cancer, breast cancer, uterine cervix cancer, lung cancer, thyroid cancer, prostate cancer, and bladder cancer were analyzed according to the coffee consumption groups using logistic regression models. The odds among individuals in the &gt;60 cups\/month coffee group were lower for gastric cancer (adjusted odds ratio (aOR) = 0.80 (95% confidence intervals = 0.65\u20130.98)), hepatic cancer (0.32 (0.18\u20130.58)), colon cancer (0.53 (0.39\u20130.72)), breast cancer (0.56 (0.45\u20130.70)), and thyroid cancer (0.71 (0.59\u20130.85)) than for individuals in the no coffee group. Physical exercise of \u2265150 min\/week was correlated with higher odds for gastric cancer (1.18 (1.03\u20131.36)), colon cancer (1.52 (1.26\u20131.83)), breast cancer (1.53 (1.35\u20131.74)), thyroid cancer (1.42 (1.27\u20131.59)), and prostate cancer (1.61 (1.13\u20132.28)) compared to no exercise. Coffee consumption and physical exercise showed an interaction in thyroid cancer (p = 0.002). Coffee consumption was related to a decreased risk of gastric cancer, hepatic cancer, colon cancer, breast cancer, and thyroid cancer in the adult population. Physical exercise was positively correlated with gastric cancer, colon cancer, breast cancer, thyroid cancer, and prostate cancer.<\/jats:p>","DOI":"10.3390\/nu13113927","type":"journal-article","created":{"date-parts":[[2021,11,2]],"date-time":"2021-11-02T22:17:23Z","timestamp":1635891443000},"page":"3927","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Association between Coffee Consumption\/Physical Exercise and Gastric, Hepatic, Colon, Breast, Uterine Cervix, Lung, Thyroid, Prostate, and Bladder Cancer"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7361-4930","authenticated-orcid":false,"given":"So Young","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology-Head & Neck Surgery, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2511-5536","authenticated-orcid":false,"given":"Dae Myoung","family":"Yoo","sequence":"additional","affiliation":[{"name":"Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14068, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0629-9299","authenticated-orcid":false,"given":"Chanyang","family":"Min","sequence":"additional","affiliation":[{"name":"Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14068, Korea"},{"name":"Graduate School of Public Health, Seoul National University, Seoul 08826, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1655-9549","authenticated-orcid":false,"given":"Hyo Geun","family":"Choi","sequence":"additional","affiliation":[{"name":"Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14068, Korea"},{"name":"Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University College of Medicine, Anyang 14068, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,11,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Bu\u0142dak, R.J., Hejmo, T., Osowski, M., Bu\u0142dak, L., Kukla, M., Polaniak, R., and Birkner, E. 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