{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T12:07:13Z","timestamp":1792584433711,"version":"4.5.0"},"reference-count":22,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T00:00:00Z","timestamp":1641513600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>The Effect of Diet on Cardiovascular Disease, Heart Disease, and Blood Vessels [...]<\/jats:p>","DOI":"10.3390\/nu14020246","type":"journal-article","created":{"date-parts":[[2022,1,9]],"date-time":"2022-01-09T20:21:56Z","timestamp":1641759716000},"page":"246","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["The Effect of Diet on Cardiovascular Disease, Heart Disease, and Blood Vessels"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3357-1809","authenticated-orcid":false,"given":"Hayato","family":"Tada","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kanazawa University, Kanazawa 920-1192, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Takamura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kanazawa University, Kanazawa 920-1192, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masa-aki","family":"Kawashiri","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kanazawa University, Kanazawa 920-1192, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e254","DOI":"10.1161\/CIR.0000000000000950","article-title":"Heart disease and stroke statistics-2021 update: A report from the American heart association","volume":"143","author":"Virani","year":"2021","journal-title":"Circulation"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/s10038-020-0818-7","article-title":"Personalized medicine for cardiovascular diseases","volume":"66","author":"Tada","year":"2021","journal-title":"J. Hum. Genet."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.jjcc.2021.09.005","article-title":"Human genetics and its impact on cardiovascular disease","volume":"79","author":"Tada","year":"2022","journal-title":"J. Cardiol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1056\/NEJMoa1605086","article-title":"Genetic risk, adherence to a healthy lifestyle, and coronary disease","volume":"375","author":"Khera","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1161\/CIRCULATIONAHA.105.581355","article-title":"Intake of fish and n3 fatty acids and risk of coronary heart disease among Japanese: The Japan public health center-based (JPHC) study cohort I","volume":"113","author":"Iso","year":"2006","journal-title":"Circulation"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.atherosclerosis.2011.05.030","article-title":"Impact of omega-3 polyunsaturated fatty acids on coronary plaque instability: An integrated backscatter intravascular ultrasound study","volume":"218","author":"Amano","year":"2011","journal-title":"Atherosclerosis"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/S0140-6736(07)60527-3","article-title":"Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): A randomised open-label, blinded endpoint analysis","volume":"369","author":"Yokoyama","year":"2007","journal-title":"Lancet"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa1812792","article-title":"Cardiovascular risk reduction with icosapent ethyl for hypertriglyceridemia","volume":"380","author":"Bhatt","year":"2019","journal-title":"N. Engl. J. Med."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Gon\u00e7alinho, G.H.F., Sampaio, G.R., Soares-Freitas, R.A.M., and Damasceno, N.R.T. (2021). Omega-3 Fatty acids in erythrocyte membranes as predictors of lower cardiovascular risk in adults without previous cardiovascular events. Nutrients, 13.","DOI":"10.3390\/nu13061919"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Jiang, L., Wang, J., Xiong, K., Xu, L., Zhang, B., and Ma, A. (2021). Intake of fish and marine n-3 polyunsaturated fatty acids and risk of cardiovascular disease mortality: A meta-analysis of prospective cohort studies. Nutrients, 13.","DOI":"10.3390\/nu13072342"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1016\/j.dsx.2019.03.033","article-title":"Trans fatty acids and lipid profile: A serious risk factor to cardiovascular disease, cancer and diabetes","volume":"13","author":"Islam","year":"2019","journal-title":"Diabetes Metab. Syndr."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Iino, T., Toh, R., Nagao, M., Shinohara, M., Harada, A., Murakami, K., Irino, Y., Nishimori, M., Yoshikawa, S., and Seto, Y. (2021). Effects of elaidic acid on HDL cholesterol uptake capacity. Nutrients, 13.","DOI":"10.3390\/nu13093112"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"128","DOI":"10.5551\/jat.ED102","article-title":"Genetic variations, triglycerides, and atherosclerotic disease","volume":"26","author":"Tada","year":"2019","journal-title":"J. Atheroscler. Thromb."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1253\/circj.CJ-19-0981","article-title":"Fasting and non-fasting triglycerides and risk of cardiovascular events in diabetic patients under statin therapy","volume":"84","author":"Tada","year":"2020","journal-title":"Circ. J."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"583","DOI":"10.5551\/jat.RV17034","article-title":"Lipoprotein(a) as an old and new causal risk factor of atherosclerotic cardiovascular disease","volume":"26","author":"Tada","year":"2019","journal-title":"J. Atheroscler. Thromb."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1056\/NEJMoa1001689","article-title":"Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis","volume":"364","author":"Khera","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Levanovich, P.E., Chung, C.S., Komnenov, D., and Rossi, N.F. (2021). Fructose plus high-salt diet in early life results in salt-sensitive cardiovascular changes in mature male sprague dawley rats. Nutrients, 13.","DOI":"10.3390\/nu13093129"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Bin-Jumah, M.N., Gilani, S.J., Hosawi, S., Al-Abbasi, F.A., Zeyadi, M., Imam, S.S., Alshehri, S., Ghoneim, M.M., Nadeem, M.S., and Kazmi, I. (2021). Pathobiological relationship of excessive dietary intake of choline\/L-carnitine: A TMAO precursor-associated aggravation in heart failure in sarcopenic patients. Nutrients, 13.","DOI":"10.3390\/nu13103453"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Shiozawa, M., Kaneko, H., Itoh, H., Morita, K., Okada, A., Matsuoka, S., Kiriyama, H., Kamon, T., Fujiu, K., and Michihata, N. (2021). Association of body mass index with ischemic and hemorrhagic stroke. Nutrients, 13.","DOI":"10.3390\/nu13072343"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/eurheartj\/ehv462","article-title":"Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history","volume":"37","author":"Tada","year":"2016","journal-title":"Eur. Heart. J."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1161\/CIRCULATIONAHA.109.192703","article-title":"Defining and setting national goals for cardiovascular health promotion and disease reduction: The American heart association\u2019s strategic impact goal through 2020 and beyond","volume":"121","author":"Hong","year":"2010","journal-title":"Circulation"},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Nishikawa, T., Tanaka, Y., Tada, H., Tsuda, T., Kato, T., Usui, S., Sakata, K., Hayashi, K., Kawashiri, M.A., and Hashiba, A. (2021). Association between cardiovascular health and incident atrial fibrillation in the general Japanese population aged 40 years. Nutrients, 13.","DOI":"10.3390\/nu13093201"}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/14\/2\/246\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T13:36:38Z","timestamp":1760362598000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/14\/2\/246"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,7]]},"references-count":22,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,1]]}},"alternative-id":["nu14020246"],"URL":"https:\/\/doi.org\/10.3390\/nu14020246","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,7]]}}}