{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T23:40:49Z","timestamp":1790293249583,"version":"4.1.0"},"reference-count":164,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2022,1,29]],"date-time":"2022-01-29T00:00:00Z","timestamp":1643414400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Immune-mediated inflammatory skin diseases are characterized by a complex multifactorial etiology, in which genetic and environmental factors interact both in genesis and development of the disease. Nutrition is a complex and fascinating scenario, whose pivotal role in induction, exacerbation, or amelioration of several human diseases has already been well documented. However, owing to the complexity of immune-mediated skin disease clinical course and breadth and variability of human nutrition, their correlation still remains an open debate in literature. It is therefore important for dermatologists to be aware about the scientific basis linking nutrition to inflammatory skin diseases such as psoriasis, atopic dermatitis, hidradenitis suppurativa, bullous diseases, vitiligo, and alopecia areata, and whether changes in diet can influence the clinical course of these diseases. The purpose of this narrative review is to address the role of nutrition in immune-mediated inflammatory skin diseases, in light of the most recent and validate knowledge on this topic. Moreover, whether specific dietary modifications could provide meaningful implementation in planning a therapeutic strategy for patients is evaluated, in accordance with regenerative medicine precepts, a healing-oriented medicine that considers the whole person, including all aspects of the lifestyle.<\/jats:p>","DOI":"10.3390\/nu14030591","type":"journal-article","created":{"date-parts":[[2022,1,30]],"date-time":"2022-01-30T00:12:56Z","timestamp":1643501576000},"page":"591","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["The Role of Nutrition in Immune-Mediated, Inflammatory Skin Disease: A Narrative Review"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2274-1742","authenticated-orcid":false,"given":"Federico","family":"Diotallevi","sequence":"first","affiliation":[{"name":"Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60100 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3740-0839","authenticated-orcid":false,"given":"Anna","family":"Campanati","sequence":"additional","affiliation":[{"name":"Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60100 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuela","family":"Martina","sequence":"additional","affiliation":[{"name":"Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60100 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3153-1026","authenticated-orcid":false,"given":"Giulia","family":"Radi","sequence":"additional","affiliation":[{"name":"Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60100 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Paolinelli","sequence":"additional","affiliation":[{"name":"Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60100 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Marani","sequence":"additional","affiliation":[{"name":"Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60100 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Molinelli","sequence":"additional","affiliation":[{"name":"Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60100 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Candelora","sequence":"additional","affiliation":[{"name":"Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60100 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Taus","sequence":"additional","affiliation":[{"name":"Dietetic Unit and Clinical Nutrition, United Hospitals of Ancona, 60100 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiziana","family":"Galeazzi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Marche Polytechnic University, 60100 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albano","family":"Nicolai","sequence":"additional","affiliation":[{"name":"Dietetic Unit and Clinical Nutrition, United Hospitals of Ancona, 60100 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annamaria","family":"Offidani","sequence":"additional","affiliation":[{"name":"Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60100 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"G\u00fcrtler, A., and Laurenz, S. (2022). The impact of clinical nutrition on inflammatory skin diseases. J. Dtsch. Dermatol. Ges., Online ahead of print.","DOI":"10.1111\/ddg.14683"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/jocd.14436","article-title":"Role of nutritional supplements in selected dermatological disorders: A review","volume":"21","author":"Sardana","year":"2021","journal-title":"J. Cosmet. Dermatol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1007\/s00296-011-1999-3","article-title":"Writing a narrative biomedical review: Considerations for authors, peer reviewers, and editors","volume":"31","author":"Gasparyan","year":"2011","journal-title":"Rheumatol. Int."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.3346\/jkms.2015.30.11.1545","article-title":"Preserving the Integrity of Citations and References by All Stakeholders of Science Communication","volume":"30","author":"Gasparyan","year":"2015","journal-title":"J. Korean Med. Sci."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/S0140-6736(14)61909-7","article-title":"Psoriasis","volume":"386","author":"Boehncke","year":"2015","journal-title":"Lancet"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1146\/annurev-immunol-032713-120225","article-title":"Immunology of Psoriasis","volume":"32","author":"Lowes","year":"2014","journal-title":"Annu. Rev. Immunol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1177\/1721727X1301100218","article-title":"Adalimumab Modulates Angiogenesis in Psoriatic Skin","volume":"11","author":"Campanati","year":"2013","journal-title":"Eur. J. Inflamm."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.4049\/jimmunol.1800013","article-title":"Discovery of the IL-23\/IL-17 Signaling Pathway and the Treatment of Psoriasis","volume":"201","author":"Hawkes","year":"2018","journal-title":"J. Immunol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1007\/s10067-018-4238-4","article-title":"Clinical outcomes and feasibility of the multidisciplinary management of patients with psoriatic arthritis: Two-year clinical experience of a dermo-rheumatologic clinic","volume":"37","author":"Luchetti","year":"2018","journal-title":"Clin. Rheumatol."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Campanati, A., Marani, A., Martina, E., Diotallevi, F., Radi, G., and Offidani, A. (2021). Psoriasis as an Immune-Mediated and Inflammatory Systemic Disease: From Pathophysiology to Novel Therapeutic Approaches. Biomedicines, 9.","DOI":"10.3390\/biomedicines9111511"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jaad.2016.07.064","article-title":"Psoriasis and comorbid diseases: Epidemiology","volume":"76","author":"Takeshita","year":"2017","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Kanda, N., Hoashi, T., and Saeki, H. (2020). Nutrition and Psoriasis. Int. J. Mol. Sci., 21.","DOI":"10.3390\/ijms21155405"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1001\/jamadermatol.2018.1412","article-title":"Dietary Recommendations for Adults with Psoriasis or Psoriatic Arthritis From the Medical Board of the National Psoriasis Foundation: A Systematic Review","volume":"154","author":"Ford","year":"2018","journal-title":"JAMA Dermatol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1517\/14712598.2014.900541","article-title":"The effect of weight reduction on treatment outcomes in obese patients with psoriasis on biologic therapy: A randomized controlled prospective trial","volume":"14","author":"Nour","year":"2014","journal-title":"Expert Opin. Biol. Ther."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.3945\/ajcn.2008.26427","article-title":"Weight loss improves the response of obese patients with moderate-tosevere chronic plaque psoriasis to low-dose cyclosporine therapy: A randomized, controlled, investigator-blinded clinical trial","volume":"88","author":"Gisondi","year":"2008","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.clnu.2013.09.010","article-title":"Energy-restricted, n-3 polyunsaturated fatty acids-rich diet improves the clinical response to immuno-modulating drugs in obese patients with plaque-type psoriasis: A randomized control clinical trial","volume":"33","author":"Guida","year":"2014","journal-title":"Clin. Nutr."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1111\/bjd.12735","article-title":"Diet and physical exercise in psoriasis: A randomized controlled trial","volume":"170","author":"Naldi","year":"2014","journal-title":"Br. J. Dermatol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1001\/jamadermatol.2013.722","article-title":"Effect of weight loss on the severity of psoriasis: A randomized clinical study","volume":"149","author":"Jensen","year":"2013","journal-title":"JAMA Dermatol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1111\/j.1468-3083.2011.04361.x","article-title":"Weight loss in obese patients with psoriasis can be successfully achieved during a course of phototherapy","volume":"26","author":"Kimball","year":"2011","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"7","DOI":"10.2174\/1389201021666200629150231","article-title":"Novel Therapeutic Approaches and Targets for Treatment of Psoriasis","volume":"22","author":"Radi","year":"2020","journal-title":"Curr. Pharm. Biotechnol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1159\/000335566","article-title":"Weight reduction alone may not be sufficient to maintain disease remission in obese patients with psoriasis: A randomized, investigator-blinded study","volume":"224","author":"Gisondi","year":"2012","journal-title":"Dermatology"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1001\/jamadermatol.2018.2127","article-title":"Association Between Mediterranean Anti-inflammatory Dietary Profile and Severity of Psoriasis: Results From the NutriNet-Sant\u00e9 Cohort","volume":"154","author":"Phan","year":"2018","journal-title":"JAMA Dermatol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1046\/j.1365-2133.2000.03240.x","article-title":"Psoriasis patients with antibodies to gliadin can be improved by a gluten-free diet","volume":"142","author":"Hagforsen","year":"2000","journal-title":"Br. J. Dermatol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1080\/00015550310015022","article-title":"Gluten-free Diet in Psoriasis Patients with Antibodies to Gliadin Results in Decreased Expression of Tissue Transglutaminase and Fewer Ki67+ Cells in the Dermis","volume":"83","author":"Hagforsen","year":"2003","journal-title":"Acta Derm. Venereol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1159\/000369615","article-title":"Association between Coeliac Disease and Psoriasis: Italian Primary Care Multicentre Study","volume":"230","author":"Gabrielli","year":"2015","journal-title":"Dermatology"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1038\/ajg.2013.79","article-title":"ACG Clinical Guidelines: Diagnosis and Management of Celiac Disease","volume":"108","author":"Hill","year":"2013","journal-title":"Am. J. Gastroenterol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1111\/jdv.13023","article-title":"Homocysteine plasma levels in psoriasis patients: Our experience and review of the literature","volume":"29","author":"Giannoni","year":"2015","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"715","DOI":"10.2340\/00015555-1801","article-title":"The Potential Effect of the Tumour Necrosis Factor-\u03b1 Inhibitors on Vitamin D Status in Psoriatic Patients","volume":"94","author":"Ganzetti","year":"2014","journal-title":"Acta Derm. Venereol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1080\/09546634.2016.1214666","article-title":"The effect of low-carbohydrates calorie-restricted diet on visceral adipose tissue and metabolic status in psoriasis patients receiving TNF-alpha inhibitors: Results of an open label controlled, prospective, clinical study","volume":"28","author":"Campanati","year":"2016","journal-title":"J. Dermatol. Treat."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1111\/ijd.12706","article-title":"Serum levels of adipocytokines in psoriasis patients receiving tumor necrosis factor-\u03b1inhibitors: Results of a retrospective analysis","volume":"54","author":"Campanati","year":"2015","journal-title":"Int. J. Dermatol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1111\/bjd.15078","article-title":"T helper (Th)1, Th17 and Th2 imbalance in mesenchymal stem cells of adult patients with atopic dermatitis: At the origin of the problem","volume":"176","author":"Orciani","year":"2017","journal-title":"Br. J. Dermatol."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Campanati, A., Bianchelli, T., Gesuita, R., Foti, C., Malara, G., Micali, G., Amerio, P., Rongioletti, F., Corazza, M., and Patrizi, A. (2021). Correction to: Comorbidities and treatment patterns in adult patients with atopic dermatitis: Results from a nationwide multicenter study. Arch. Dermatol. Res., Online ahead of print.","DOI":"10.1007\/s00403-021-02266-3"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.clindermatol.2010.03.032","article-title":"Atopic dermatitis and nutrition","volume":"28","author":"Finch","year":"2010","journal-title":"Clin. Dermatol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/pde.14004","article-title":"Food restriction, nutrition status, and growth in toddlers with atopic dermatitis","volume":"37","author":"Low","year":"2019","journal-title":"Pediatr. Dermatol."},{"key":"ref_35","first-page":"5","article-title":"Review of evidence for dietary influences on atopic dermatitis","volume":"19","author":"Mohajeri","year":"2014","journal-title":"Skin Ther. Lett."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1590\/abd1806-4841.20132072","article-title":"Atopic Dermatitis, food allergy and dietary interventions. A tale of controversy","volume":"88","author":"Guibas","year":"2013","journal-title":"An. Bras. Dermatol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"332","DOI":"10.4103\/0378-6323.79715","article-title":"Food allergen-free diet in severe atopic dermatitis related to food allergy","volume":"77","author":"Anyfantakis","year":"2011","journal-title":"Indian J. Dermatol. Venereol. Leprol."},{"key":"ref_38","first-page":"8775313","article-title":"Therapeutic effectiveness of treatment with an elimination diet in children with atopic dermatitis of different ages","volume":"40","author":"Kaczmarski","year":"1995","journal-title":"Rocz. Akad. Med. Bialymst."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"95","DOI":"10.3390\/medicina45020013","article-title":"Significance of dietotherapy on the clinical course of atopic dermatitis","volume":"45","author":"Labanauskas","year":"2009","journal-title":"Medicina"},{"key":"ref_40","first-page":"227","article-title":"Diet and atopic dermatitis","volume":"97","author":"Silverberg","year":"2016","journal-title":"Cutis"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Kim, M.J., Kim, S.-N., Lee, Y.W., Choe, Y.B., and Ahn, K.J. (2016). Vitamin D Status and Efficacy of Vitamin D Supplementation in Atopic Dermatitis: A Systematic Review and Meta-Analysis. Nutrients, 8.","DOI":"10.3390\/nu8120789"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1002\/bjs.6569","article-title":"Hidradenitis suppurativa","volume":"96","author":"Buimer","year":"2009","journal-title":"Br. J. Surg."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1001\/jama.2017.16691","article-title":"Hidradenitis suppurativa: Advances in diagnosis and treatment","volume":"318","author":"Saunte","year":"2017","journal-title":"JAMA"},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Sabat, R., Chanwangpong, A., Schneider-Burrus, S., Metternich, D., Kokolakis, G., Kurek, A., Philipp, S., Uribe, D., Wolk, K., and Sterry, W. (2012). Increased Prevalence of Metabolic Syndrome in Patients with Acne Inversa. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0031810"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1001\/jamadermatol.2018.2516","article-title":"Pathogenetic Characteristics of Mesenchymal Stem Cells in Hidradenitis Suppurativa","volume":"154","author":"Campanati","year":"2018","journal-title":"JAMA Dermatol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1111\/ijd.14465","article-title":"Diet in hidradenitis suppurativa: A review of published and lay literature","volume":"58","author":"Youssef","year":"2019","journal-title":"Int. J. Dermatol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"e12841","DOI":"10.1111\/dth.12841","article-title":"Two cases of Hidradenitis suppurativa and botulinum toxin type a therapy: A novel approach for a pathology that is still difficult to manage","volume":"32","author":"Campanati","year":"2019","journal-title":"Dermatol. Ther."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1159\/000503063","article-title":"Prevalence and Impact of Dietary Avoidance among Individuals with Hidradenitis Suppurativa","volume":"236","author":"Dempsey","year":"2020","journal-title":"Dermatology"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1177\/1203475419874412","article-title":"Weight Loss and Dietary Interventions for Hidradenitis Suppurativa: A Systematic Review","volume":"24","author":"Sivanand","year":"2019","journal-title":"J. Cutan. Med. Surg."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"e14246","DOI":"10.1111\/dth.14246","article-title":"Alleviating and exacerbating foods in hidradenitis suppurativa","volume":"33","author":"Fernandez","year":"2020","journal-title":"Dermatol. Ther."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"553","DOI":"10.2340\/00015555-1800","article-title":"The Influence of Body Weight on the Prevalence and Severity of Hidradenitis Suppurativa","volume":"94","author":"Kromann","year":"2014","journal-title":"Acta Derm. Venereol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1001\/jamadermatol.2014.1165","article-title":"Association of Metabolic Syndrome and Hidradenitis Suppurativa","volume":"150","author":"Miller","year":"2014","journal-title":"JAMA Dermatol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1016\/j.jid.2020.04.011","article-title":"Lipidomics Profiling of Hidradenitis Suppurativa Skin Lesions Reveals Lipoxygenase Pathway Dysregulation and Accumulation of Proinflammatory Leukotriene B4","volume":"140","author":"Penno","year":"2020","journal-title":"J. Investig. Dermatol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1111\/jdv.12857","article-title":"Verneuil\u2019s disease, innate immunity and vitamin D: A pilot study","volume":"29","author":"Guillet","year":"2014","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"e126","DOI":"10.1111\/ced.13922","article-title":"Hidradenitis suppurativa and diabetes mellitus: Updated systematic review and adjusted meta-analysis","volume":"44","author":"Phan","year":"2019","journal-title":"Clin. Exp. Dermatol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1111\/j.1468-3083.2009.03188.x","article-title":"Guidelines for the diagno-sis and treatment of dermatitis herpetiformis","volume":"23","author":"Caproni","year":"2009","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1111\/j.1365-2133.2011.10385.x","article-title":"Prevalence and incidence of dermatitis herpetiformis: A 40-year prospective study from Finland","volume":"165","author":"Salmi","year":"2011","journal-title":"Br. J. Dermatol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1046\/j.1365-4362.2003.01804.x","article-title":"Dermatitis herpetiformis","volume":"42","author":"Nicolas","year":"2003","journal-title":"Int. J. Dermatol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1080\/17425255.2019.1600670","article-title":"Metabolic, pharmacokinetic, and toxicological issues surrounding dapsone","volume":"15","author":"Molinelli","year":"2019","journal-title":"Expert Opin. Drug Metab. Toxicol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"6","DOI":"10.5070\/D32622H9K7","article-title":"Dermatitis herpetiformis and gluten-free diet","volume":"11","author":"Turchin","year":"2005","journal-title":"Dermatol. Online J."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"11825","DOI":"10.3748\/wjg.v21.i41.11825","article-title":"Role of oats in celiac disease","volume":"21","author":"Comino","year":"2015","journal-title":"World J. Gastroenterol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"e198","DOI":"10.1111\/bjd.15995","article-title":"Disappearance of epidermal transglutaminase and IgA deposits from the papillary dermis of patients with dermatitis herpetiformis after a long-term gluten-free diet","volume":"178","author":"Hietikko","year":"2018","journal-title":"Br. J. Dermatol."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1753-4887.2010.00368.x","article-title":"Celiac disease, gluten-free diet, and oats","volume":"69","author":"Fric","year":"2011","journal-title":"Nutr. Rev."},{"key":"ref_64","first-page":"519","article-title":"The Gluten-Free Diet: A Nutritional Risk Factor for Adolescents with Celiac Disease?","volume":"27","author":"Mariani","year":"1998","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s00217-007-0702-0","article-title":"Evaluation of the nutritional quality of the lipid fraction of glu-ten-free biscuits","volume":"223","author":"Caponio","year":"2008","journal-title":"Eur. Food Res. Technol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1007\/s00394-018-1685-2","article-title":"Glu-ten-Free-Rendered Products Contribute to Imbalanced Diets in Children and Adolescents with Celiac Disease","volume":"58","author":"Larretxi","year":"2019","journal-title":"Eur. J. Nutr."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1097\/MPG.0000000000001251","article-title":"Patients with Celiac Disease Reported Higher Consumption of Added Sugar and Total Fat Than Healthy Individuals","volume":"64","author":"Babio","year":"2017","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1017\/S0007114515002056","article-title":"Are gluten-free foods healthier than non-gluten-free foods? An evaluation of supermarket products in Australia","volume":"114","author":"Wu","year":"2015","journal-title":"Br. J. Nutr."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"S128","DOI":"10.1053\/j.gastro.2005.02.020","article-title":"The gluten-free diet: How to provide effective education and resources","volume":"128","author":"Case","year":"2005","journal-title":"Gastroenterology"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"599","DOI":"10.23736\/S0392-0488.18.06073-X","article-title":"Italian Guidelines in Pemphigus\u2014Adapted from the European Dermatology Forum (EDF) and European Academy of Dermatology and Venerology (EADV)","volume":"153","author":"Feliciani","year":"2018","journal-title":"G. Ital. Dermatol. Venereol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"137","DOI":"10.4103\/0019-5154.80403","article-title":"Scoring systems in pemphigus","volume":"56","author":"Grover","year":"2011","journal-title":"Indian J. Dermatol."},{"key":"ref_72","unstructured":"Champion, R.H., and Pye, R.J. (1990). Intensive care in Dermatology. Recent Advances in Dermatology, Churchill Livingstone."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0377-1237(17)30554-3","article-title":"Recent Trends in the Management of Pemphigus Vulgaris","volume":"54","author":"Kar","year":"1998","journal-title":"Med. J. Armed Forces India"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1111\/jdv.16752","article-title":"Updated S2K guidelines on the management of pemphigus vulgaris and foliaceus initiated by the european academy of dermatology and venereology (EADV)","volume":"34","author":"Joly","year":"2020","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_75","first-page":"1544","article-title":"Evaluation of Vitamin D Status in Newly Diagnosed Pemphigus Vulgaris Patients","volume":"43","author":"Zarei","year":"2014","journal-title":"Iran. J. Public Health"},{"key":"ref_76","first-page":"581","article-title":"Vitamin D3 inhibits expression of pemphigus vulgaris antigen desmoglein 3: Implication of a partial mechanism in the pharmacological effect of vitamin D3 on skin diseases","volume":"1","author":"Yamamoto","year":"2008","journal-title":"Mol. Med. Rep."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1590\/abd1806-4841.20188235","article-title":"Fogo selvagem: Endemic pemphigus foliaceus","volume":"93","author":"Aoki","year":"2018","journal-title":"Bras Dermatol."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1159\/000246874","article-title":"Possible Nutritional Factors in Induced Pemphigus","volume":"189","author":"Brenner","year":"1994","journal-title":"Dermatology"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1001\/archderm.134.11.1406","article-title":"In pursuit exogenous factors in pemphigus and fogo selvagem","volume":"134","author":"Tur","year":"1998","journal-title":"Arch. Dermatol."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.clindermatol.2013.05.004","article-title":"The role of nutrition in dermatologic diseases: Facts and controversies","volume":"31","author":"Lakdawala","year":"2013","journal-title":"Clin. Dermatol."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.clindermatol.2010.03.036","article-title":"Nutrition and bullous skin diseases","volume":"28","author":"Fedeles","year":"2010","journal-title":"Clin. Dermatol."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1001\/archderm.134.9.1075","article-title":"Evaluation of clinical criteria for diagnosis of bullous pemphigoid. French Bullous Study Group","volume":"134","author":"Vaillant","year":"1998","journal-title":"Arch. Dermatol."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1600-0536.1993.tb03520.x","article-title":"Dyshidrosiform pemphigoid induced by nickel in the diet","volume":"29","author":"Atakan","year":"1993","journal-title":"Contact Dermat."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1111\/j.1468-3083.1998.tb00778.x","article-title":"Endomysium and antigliadin antibodies in dermatitis herpetiformis and other bullous diseases","volume":"11","author":"Economidou","year":"1998","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"15011","DOI":"10.1038\/nrdp.2015.11","article-title":"Vitiligo","volume":"1","author":"Picardo","year":"2015","journal-title":"Nat. Rev. Dis. Primers"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.jaad.2010.11.061","article-title":"Vitiligo: A comprehensive overview Part, I. Introduction, epidemiolo-gy, quality of life, diagnosis, differential diagnosis, associations, histopathology, etiology, and work-up","volume":"65","author":"Alikhan","year":"2011","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0140-6736(14)60763-7","article-title":"Vitiligo","volume":"386","author":"Ezzedine","year":"2015","journal-title":"Lancet"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/j.jaad.2014.12.012","article-title":"Patient satisfaction with different treatment modalities for vitiligo","volume":"72","author":"Adotama","year":"2015","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.det.2016.11.012","article-title":"The Role of Diet and Supplements in Vitiligo Management","volume":"35","author":"Grimes","year":"2017","journal-title":"Dermatol. Clin."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1159\/000370303","article-title":"Rapid partial repigmentation of vitiligo in a young female adult with a gluten-free diet","volume":"6","author":"Khandalavala","year":"2014","journal-title":"Case Rep. Dermatol."},{"key":"ref_91","first-page":"171","article-title":"Vitiligo. Successful treatment with dapsone","volume":"5","author":"Salafia","year":"1995","journal-title":"Chron. Dermatol."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/j.1525-1470.2011.01388.x","article-title":"Repigmentation of Vitiligo Lesions in a Child with Celiac Disease after a Gluten-Free Diet","volume":"28","author":"Fagundo","year":"2011","journal-title":"Pediatr. Dermatol."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1007\/BF00414110","article-title":"Phenylalanine and UVA light for the treatment of vitiligo","volume":"277","author":"Cormane","year":"1985","journal-title":"Arch. Dermatol. Res."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1159\/000247142","article-title":"L-Phenylalanine and UVA Irradiation in the Treatment of Vitiligo","volume":"188","author":"Siddiqui","year":"1994","journal-title":"Dermatology"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/j.1365-4362.1989.tb04613.x","article-title":"Vitiligo Therapy with Oral and Topical Phenylalanine with UVA Exposure","volume":"28","author":"Antoniou","year":"1989","journal-title":"Int. J. Dermatol."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1111\/j.1529-8019.2012.01484.x","article-title":"Clinical efficacy of a novel topical formulation for vitiligo: Compared evaluation of different treatment modalities in 149 patients","volume":"25","author":"Buggiani","year":"2012","journal-title":"Dermatol. Ther."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1021\/pr050361j","article-title":"Counting the Zinc-Proteins Encoded in the Human Genome","volume":"5","author":"Andreini","year":"2006","journal-title":"J. Proteome Res."},{"key":"ref_98","first-page":"93","article-title":"Zinc: An overview","volume":"11","author":"Prasad","year":"1994","journal-title":"Nutrition"},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"206","DOI":"10.4103\/0378-6323.16243","article-title":"Serum zinc level in vitiligo: A case control study","volume":"71","author":"Prasad","year":"2005","journal-title":"Indian J. Dermatol. Venereol. Leprol."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"52","DOI":"10.4103\/ijpvm.IJPVM_47_17","article-title":"Role of fatty acids intake in generalized vitiligo","volume":"10","author":"Jaffary","year":"2019","journal-title":"Int. J. Prev. Med."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1111\/j.1365-2230.2007.02514.x","article-title":"Antioxidants and narrow band-UVB in the treatment of vitiligo: A double-blind placebo controlled trial","volume":"32","author":"Mastrofrancesco","year":"2007","journal-title":"Clin. Exp. Dermatol."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1089\/acm.2020.0292","article-title":"A Systematic Review of Nutrition, Supplement, and Herbal-Based Adjunctive Therapies for Vitiligo","volume":"27","author":"Shakhbazova","year":"2021","journal-title":"J. Altern. Complement. Med."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"460","DOI":"10.2340\/000155555577460462","article-title":"Improvement of vitiligo after oral treatment with vitamin B12 and folic acid and the importance of sun exposure","volume":"77","author":"Juhlin","year":"1977","journal-title":"Acta Derm. Venereol."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1080\/000155502320624113","article-title":"Treatment of Vitiligo Vulgaris with Narrow Band UVB (311 nm) for One Year and the Effect of Addition of Folic Acid and Vitamin B12","volume":"82","author":"Tjioe","year":"2002","journal-title":"Acta Derm. Venereol."},{"key":"ref_105","unstructured":"Park, K.K., and Murase, J.E. (2011). Complementary and Alternative Medicine for Vitiligo. Vitiligo: Management and Therapy, INTECH Open Access Publisher."},{"key":"ref_106","first-page":"4","article-title":"Ascorbic acid in vitiligo","volume":"26","author":"Bhattacharya","year":"1981","journal-title":"Indian J. Dermatol."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1159\/000342124","article-title":"The Antioxidant Role of Paraoxonase 1 and Vitamin E in Three Autoimmune Diseases","volume":"26","author":"Ramadan","year":"2013","journal-title":"Ski. Pharmacol. Physiol."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1177\/0091270009335769","article-title":"Response of Vitiligo to Narrowband Ultraviolet B and Oral Antioxidants","volume":"49","author":"Elgoweini","year":"2009","journal-title":"J. Clin. Pharmacol."},{"key":"ref_109","first-page":"11809591","article-title":"The effects of vitamin E on the skin lipid peroxidation and the clinical improvement in vitiligo patients treated with PUVA","volume":"12","author":"Akyol","year":"2002","journal-title":"Eur. J. Dermatol."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"222","DOI":"10.4161\/derm.24808","article-title":"A pilot study assessing the effect of prolonged administration of high daily doses of vitamin D on the clinical course of vitiligo and psoriasis","volume":"5","author":"Finamor","year":"2013","journal-title":"Dermato-Endocrinology"},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.fitote.2014.08.007","article-title":"The therapeutic effects of EGCG on vitiligo","volume":"99","author":"Zhu","year":"2014","journal-title":"Fitoterapia"},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1046\/j.1365-2230.2003.01207.x","article-title":"Effectiveness of oral Ginkgo biloba in treating limited, slowly spreading vitiligo","volume":"28","author":"Parsad","year":"2003","journal-title":"Clin. Exp. Dermatol."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1472-6882-11-21","article-title":"Ginkgo biloba for the treatment of vitilgo vulgaris: An open label pilot clinical trial","volume":"11","author":"Szczurko","year":"2011","journal-title":"BMC Complement. Altern. Med."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"e12625","DOI":"10.1111\/dth.12625","article-title":"Functional nutrition as integrated approach in vitiligo management","volume":"32","author":"Barygina","year":"2019","journal-title":"Dermatol. Ther."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.jdermsci.2009.02.004","article-title":"Ultrastructural and functional alterations of mitochondria in perilesional vitiligo skin","volume":"54","author":"Prignano","year":"2009","journal-title":"J. Dermatol. Sci."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1089\/pho.2009.2637","article-title":"Tetrahydrocurcuminoid Cream Plus Targeted Narrowband UVB Phototherapy for Vitiligo: A Preliminary Randomized Controlled Study","volume":"28","author":"Asawanonda","year":"2010","journal-title":"Photomed. Laser Surg."},{"key":"ref_117","first-page":"224","article-title":"Polypodium leucotomos\u2014An Overview of Basic Investigative Findings","volume":"15","author":"Berman","year":"2016","journal-title":"J. Drugs Dermatol."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1111\/j.1468-3083.2006.02132.x","article-title":"Treatment of vitiligo vulgaris with narrow-band UVB and oral Polypodium leucotomos extract: A randomized double-blind placebo-controlled study","volume":"21","author":"Bos","year":"2007","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1111\/j.1365-4362.1989.tb02517.x","article-title":"Vitiligo repigmentation with Anapsos (Polypodium leucotomos)","volume":"28","author":"Mohammad","year":"1989","journal-title":"Int. J. Dermatol."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1093\/jn\/133.1.98","article-title":"Supplementation with \u03b2-Carotene or a Similar Amount of Mixed Carotenoids Protects Humans from UV-Induced Erythema","volume":"133","author":"Heinrich","year":"2003","journal-title":"J. Nutr."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/S0190-9622(88)70092-4","article-title":"Treatment of vitiligo with khellin and ultraviolet A","volume":"18","author":"Ortel","year":"1988","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"e4515","DOI":"10.5812\/ircmj.4515","article-title":"Comparing Nigella sativa Oil and Fish Oil in Treatment of Vitiligo","volume":"16","author":"Ghorbanibirgani","year":"2014","journal-title":"Iran. Red Crescent Med. J."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1111\/bjd.16808","article-title":"Alopecia areata: A review of disease pathogenesis","volume":"179","author":"Rajabi","year":"2018","journal-title":"Br. J. Dermatol."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.jaad.2009.10.032","article-title":"Alopecia areata update: Part I. Clinical picture, histopathology, and pathogenesis","volume":"62","author":"Alkhalifah","year":"2010","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.jaad.2019.08.032","article-title":"Epidemiology of alopecia areata, ophiasis, totalis, and universalis: A systematic review and meta-analysis","volume":"82","author":"Lee","year":"2020","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s12016-017-8620-9","article-title":"Alopecia Areata: A Comprehensive Review of Pathogenesis and Management","volume":"54","author":"Dias","year":"2018","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1046\/j.1087-0024.2003.00807.x","article-title":"The Hair Follicle and Immune Privilege","volume":"8","author":"Paus","year":"2003","journal-title":"J. Investig. Dermatol. Symp. Proc."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1172\/JCI31942","article-title":"Lymphocytes, neuropeptides, and genes involved in alopecia areata","volume":"117","author":"Gilhar","year":"2007","journal-title":"J. Clin. Investig."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"17011","DOI":"10.1038\/nrdp.2017.11","article-title":"Alopecia areata","volume":"3","author":"Pratt","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"e045718","DOI":"10.1136\/bmjopen-2020-045718","article-title":"Epidemiology, management and the associated burden of mental health illness, atopic and autoimmune conditions, and com-mon infections in alopecia areata: Protocol for an observational study series","volume":"11","author":"Harries","year":"2021","journal-title":"BMJ Open"},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"e503","DOI":"10.1016\/j.crohns.2012.05.023","article-title":"Alopecia Areata: A possible extraintestinal manifestation of Crohn\u2019s disease","volume":"6","author":"Ganzetti","year":"2012","journal-title":"J. Crohn\u2019s Colitis"},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.jaad.2018.07.013","article-title":"Comorbidities in alopecia areata: A systematic review and meta-analysis","volume":"80","author":"Lee","year":"2019","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s11154-011-9194-0","article-title":"Vitamin D and the skin: Physiology and pathophysiology","volume":"13","author":"Bikle","year":"2011","journal-title":"Rev. Endocr. Metab. Disord."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"872","DOI":"10.2310\/JIM.0b013e318214ea2d","article-title":"Vitamin D: A d-lightful solution for health","volume":"59","author":"Holick","year":"2011","journal-title":"J. Investig. Med."},{"key":"ref_135","first-page":"156","article-title":"The Vitamin D Receptor and the Syndrome of Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets*","volume":"20","author":"Malloy","year":"1999","journal-title":"Endocr. Rev."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1046\/j.1523-1747.2002.01644.x","article-title":"Lack of the Vitamin D Receptor is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth","volume":"118","author":"Xie","year":"2002","journal-title":"J. Investig. Dermatol."},{"key":"ref_137","doi-asserted-by":"crossref","unstructured":"Sassi, F., Tamone, C., and D\u2019Amelio, P. (2018). Vitamin D: Nutrient, Hormone, and Immunomodulator. Nutrients, 10.","DOI":"10.3390\/nu10111656"},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"371","DOI":"10.4103\/2229-5178.190504","article-title":"Serum Vitamin D in patients with alopecia areata","volume":"7","author":"Bakry","year":"2016","journal-title":"Indian Dermatol. Online J."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1111\/bjd.12980","article-title":"Vitamin D deficiency in alopecia areata","volume":"170","author":"Cerman","year":"2014","journal-title":"Br. J. Dermatol."},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s10238-018-0511-8","article-title":"An investigation of vitamin D status in alopecia areata","volume":"18","author":"Gade","year":"2018","journal-title":"Clin. Exp. Med."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/ijd.13851","article-title":"Correlation of vitamin D and vitamin D receptor expression in patients with alopecia areata: A clinical paradigm","volume":"57","author":"Daroach","year":"2018","journal-title":"Int. J. Dermatol."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/jocd.12352","article-title":"Serum vitamin D level is related to disease severity in pediatric alopecia areata","volume":"17","author":"Unal","year":"2017","journal-title":"J. Cosmet. Dermatol."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s13555-020-00379-7","article-title":"Efficacy and Safety of Topical Calcipotriol 0.005% Versus Topical Clobetasol 0.05% in the Management of Alopecia Areata: An Intrasubject Pilot Study","volume":"10","author":"Molinelli","year":"2020","journal-title":"Dermatol. Ther."},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"123","DOI":"10.4103\/ijt.ijt_18_19","article-title":"Comparative Study of Efficacy of Topical Mometasone with Calcipotriol versus Mometasone Alone in the Treatment of Alopecia Areata","volume":"11","author":"Alam","year":"2019","journal-title":"Int. J. Trichol."},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"192","DOI":"10.5409\/wjcp.v10.i6.192","article-title":"Treatment of alopecia totalis\/universalis\/focalis with vitamin D and analogs: Three case reports and a literature review","volume":"10","author":"Papadimitriou","year":"2021","journal-title":"World J. Clin. Pediatr."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"e12464","DOI":"10.1111\/dth.12464","article-title":"Efficacy and safety of topical calcipotriol in management of alopecia areata: A pilot study","volume":"30","author":"Narang","year":"2017","journal-title":"Dermatol. Ther."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"341","DOI":"10.5021\/ad.2012.24.3.341","article-title":"Successful Treatment of Alopecia Areata with Topical Calcipotriol","volume":"24","author":"Kim","year":"2012","journal-title":"Ann. Dermatol."},{"key":"ref_148","first-page":"24","article-title":"Faecal short-chain fatty acid pattern in childhood coeliac disease is normalised after more than one year\u2019s gluten-free diet","volume":"24","author":"Stenhammar","year":"2013","journal-title":"Microb. Ecol. Health Dis."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1046\/j.1440-1754.2003.00116.x","article-title":"Coeliac disease and alopecia areata in childhood","volume":"39","author":"Fessatou","year":"2003","journal-title":"J. Paediatr. Child Health"},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1046\/j.1365-2230.1998.00357.x","article-title":"Alopecia and coeliac disease: Report of two patients showing response to gluten-free diet","volume":"23","author":"Barbato","year":"1998","journal-title":"Clin. Exp. Dermatol."},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1159\/000504786","article-title":"The Role of Diet as an Adjuvant Treatment in Scarring and Nonscarring Alopecia","volume":"6","author":"Pham","year":"2020","journal-title":"Ski. Appendage Disord."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1365-2133.1994.tb08515.x","article-title":"Alkaline phosphatase activity and localization during the murine hair cycle","volume":"131","author":"Handjiski","year":"1994","journal-title":"Br. J. Dermatol."},{"key":"ref_153","first-page":"43","article-title":"Oxidative stress and alopecia areata","volume":"8","author":"Prie","year":"2015","journal-title":"J. Med. Life"},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s40257-017-0285-x","article-title":"The Role of Micronutrients in Alopecia Areata: A Review","volume":"18","author":"Thompson","year":"2017","journal-title":"Am. J. Clin. Dermatol."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.det.2012.08.015","article-title":"Nutrition and hair: Deficiencies and supplements","volume":"31","author":"Finner","year":"2013","journal-title":"Dermatol. Clin."},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"142","DOI":"10.5021\/ad.2009.21.2.142","article-title":"The Therapeutic Effect and the Changed Serum Zinc Level after Zinc Supplementation in Alopecia Areata Patients Who Had a Low Serum Zinc Level","volume":"21","author":"Park","year":"2009","journal-title":"Ann. Dermatol."},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1525-1470.1999.pdele65.x","article-title":"Zinc Aspartate, Biotin, and Clobetasol Propionate in the Treatment of Alopecia Areata in Childhood","volume":"16","author":"Camacho","year":"1999","journal-title":"Pediatr. Dermatol."},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/dth.12215","article-title":"Combination therapy with zinc gluconate and PUVA for alopecia areata totalis: An adjunctive but crucial role of zinc supplementation","volume":"28","year":"2015","journal-title":"Dermatol. Ther."},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/j.1365-2133.1981.tb15323.x","article-title":"Oral zinc sulphate in alopacia areata\u2014A double blind trial","volume":"104","author":"Ead","year":"1981","journal-title":"Br. J. Dermatol."},{"key":"ref_160","unstructured":"World Health Organization, and Centers for Disease Control and Prevention (2004). Assessing the Iron Status of Populations, World Health Organization. [2nd ed.]."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/j.jaad.2005.11.1104","article-title":"The diagnosis and treatment of iron deficiency and its potential relationship to hair loss","volume":"54","author":"Trost","year":"2006","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1038\/nature05485","article-title":"Inflammation and metabolic disorders","volume":"444","author":"Hotamisligil","year":"2006","journal-title":"Nature"},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"427","DOI":"10.25259\/IJDVL_726_19","article-title":"A cross-sectional study of metabolic syndrome in patients with alope-cia areata","volume":"87","author":"Nasimi","year":"2021","journal-title":"Indian J. Dermatol. Venereol. Leprol."},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"e14979","DOI":"10.1111\/dth.14979","article-title":"Metabolic syndrome in patients with Alopecia Areata: A case-control study","volume":"34","author":"Abdollahimajd","year":"2021","journal-title":"Dermatol. Ther."}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/14\/3\/591\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:10:38Z","timestamp":1760134238000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/14\/3\/591"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,29]]},"references-count":164,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,2]]}},"alternative-id":["nu14030591"],"URL":"https:\/\/doi.org\/10.3390\/nu14030591","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,29]]}}}