{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:45:17Z","timestamp":1762508717865,"version":"build-2065373602"},"reference-count":40,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,2,13]],"date-time":"2022-02-13T00:00:00Z","timestamp":1644710400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfeicoamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Inadequate nutrient intake can lead to worse outcomes in patients with heart failure (HF). This prospective cohort study aimed to assess the prevalence of inadequate micronutrient intake and their association with prognosis in 121 adult and elderly outpatients with HF. Habitual micronutrient intake was evaluated using 24-h dietary recalls (minimum 2 and maximum 6). Participants were grouped into moderate (n = 67) and high (n = 54) micronutrient deficiency groups, according to the individual assessment of each micronutrient intake. Patients\u2019 sociodemographic, clinical, and anthropometric data and clinical outcomes (hospitalization and mortality) within 24 months were collected. Overall and event-free survival rates were calculated using Kaplan\u2013Meier estimates, and curves were compared using the log-rank test. The death risk rate (hazard ratio (HR)) was calculated using Cox\u2019s univariate model. The rate of inadequate intake was 100% for vitamins B1 and D and above 80% for vitamins B2, B9, and E, calcium, magnesium, and copper. No differences in overall survival and event-free survival were observed between groups of HF outpatients with moderate and high micronutrient deficiencies (HR = 0.94 (CI = 0.36\u20132.48), p = 0.91, and HR = 1.63 (CI = 0.68\u20133.92), p = 0.26, respectively), as well as when the inadequacy of each micronutrient intake was evaluated alone (all p &gt; 0.05). In conclusion, a high prevalence of inadequate micronutrient intake was observed in outpatients with HF. Inadequate micronutrient intake was not associated with hospitalization and mortality in this group of patients.<\/jats:p>","DOI":"10.3390\/nu14040788","type":"journal-article","created":{"date-parts":[[2022,2,13]],"date-time":"2022-02-13T20:34:45Z","timestamp":1644784485000},"page":"788","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Lack of Association between Inadequate Micronutrient Intake and Prognosis in Outpatients with Heart Failure"],"prefix":"10.3390","volume":"14","author":[{"given":"N\u00fabia Rafaella Soares Moreira","family":"Torres","sequence":"first","affiliation":[{"name":"Postgraduate Program in Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, 3000, Senador Salgado Filho Avenue, Lagoa Nova, Natal 59078-970, Rio Grande do Norte, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6039-0395","authenticated-orcid":false,"given":"Fernanda Lambert de Andrade","family":"Freire","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, 3000, Senador Salgado Filho Avenue, Lagoa Nova, Natal 59078-970, Rio Grande do Norte, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8517-6811","authenticated-orcid":false,"given":"Raquel Costa Silva","family":"Dantas-Komatsu","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Health Sciences, Center for Health Sciences, Federal University of Rio Grande do Norte, 620, Nilo Pe\u00e7anha Avenue, Petr\u00f3polis, Natal 59012-300, Rio Grande do Norte, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8146-0724","authenticated-orcid":false,"given":"Eduardo Paix\u00e3o da","family":"Silva","sequence":"additional","affiliation":[{"name":"Multiprofessional Residency in Health\u2014Cardiology, Onofre Lopes University Hospital, Federal University of Rio Grande do Norte, 620, Nilo Pe\u00e7anha Avenue, Petr\u00f3polis, Natal 59012-300, Rio Grande do Norte, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salom\u00e3o Israel Monteiro Louren\u00e7o","family":"Queiroz","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Public Health, Health Sciences Center, Federal University of Rio Grande do Norte, 3000, Senador Salgado Filho Avenue, Lagoa Nova, Natal 59078-970, Rio Grande do Norte, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niethia Regina Dantas de","family":"Lira","sequence":"additional","affiliation":[{"name":"Multiprofessional Residency in Health\u2014Cardiology, Onofre Lopes University Hospital, Federal University of Rio Grande do Norte, 620, Nilo Pe\u00e7anha Avenue, Petr\u00f3polis, Natal 59012-300, Rio Grande do Norte, Brazil"},{"name":"Brazilian Hospital Services Company, Onofre Lopes University Hospital, Federal University of Rio Grande do Norte, 620, Nilo Pe\u00e7anha Avenue, Petr\u00f3polis, Natal 59012-300, Rio Grande do Norte, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3883-2780","authenticated-orcid":false,"given":"Rosiane Viana Zuza","family":"Diniz","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Center for Health Sciences, Federal University of Rio Grande do Norte, 620, Nilo Pe\u00e7anha Avenue, Petr\u00f3polis, Natal 59012-300, Rio Grande do Norte, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Severina Carla Vieira Cunha","family":"Lima","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, 3000, Senador Salgado Filho Avenue, Lagoa Nova, Natal 59078-970, Rio Grande do Norte, Brazil"},{"name":"Multiprofessional Residency in Health\u2014Cardiology, Onofre Lopes University Hospital, Federal University of Rio Grande do Norte, 620, Nilo Pe\u00e7anha Avenue, Petr\u00f3polis, Natal 59012-300, Rio Grande do Norte, Brazil"},{"name":"Department of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, 3000, Senador Salgado Filho Avenue, Lagoa Nova, Natal 59078-970, Rio Grande do Norte, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5436-5115","authenticated-orcid":false,"given":"Lucia Fatima Campos","family":"Pedrosa","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, 3000, Senador Salgado Filho Avenue, Lagoa Nova, Natal 59078-970, Rio Grande do Norte, Brazil"},{"name":"Department of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, 3000, Senador Salgado Filho Avenue, Lagoa Nova, Natal 59078-970, Rio Grande do Norte, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0011-576X","authenticated-orcid":false,"given":"M\u00e1rcia Mar\u00edlia Gomes Dantas","family":"Lopes","sequence":"additional","affiliation":[{"name":"Multiprofessional Residency in Health\u2014Cardiology, Onofre Lopes University Hospital, Federal University of Rio Grande do Norte, 620, Nilo Pe\u00e7anha Avenue, Petr\u00f3polis, Natal 59012-300, Rio Grande do Norte, Brazil"},{"name":"Department of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, 3000, Senador Salgado Filho Avenue, Lagoa Nova, Natal 59078-970, Rio Grande do Norte, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9729-1243","authenticated-orcid":false,"given":"Karine Cavalcanti Maur\u00edcio","family":"Sena-Evangelista","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, 3000, Senador Salgado Filho Avenue, Lagoa Nova, Natal 59078-970, Rio Grande do Norte, Brazil"},{"name":"Postgraduate Program in Health Sciences, Center for Health Sciences, Federal University of Rio Grande do Norte, 620, Nilo Pe\u00e7anha Avenue, Petr\u00f3polis, Natal 59012-300, Rio Grande do Norte, Brazil"},{"name":"Department of Clinical Medicine, Center for Health Sciences, Federal University of Rio Grande do Norte, 620, Nilo Pe\u00e7anha Avenue, Petr\u00f3polis, Natal 59012-300, Rio 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