{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T06:47:17Z","timestamp":1781851637355,"version":"3.54.5"},"reference-count":48,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,3,27]],"date-time":"2022-03-27T00:00:00Z","timestamp":1648339200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100020391","name":"Christina Barz-Stiftung","doi-asserted-by":"publisher","award":["T0155 -31.954"],"award-info":[{"award-number":["T0155 -31.954"]}],"id":[{"id":"10.13039\/501100020391","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006211","name":"Humboldt-Universit\u00e4t zu Berlin","doi-asserted-by":"publisher","award":["H67029"],"award-info":[{"award-number":["H67029"]}],"id":[{"id":"10.13039\/501100006211","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>In the USA, family-based treatment (FBT) with inpatient medical stabilization as needed is the leading evidence-based treatment for youth with anorexia nervosa (AN). In continental Europe, typically inpatient multimodal treatment targeting weight recovery followed by outpatient care (IMT) is standard care, if prior outpatient treatment was not sufficient. Our aim was to compare weekly weight gain and hospital days over six months for adolescents receiving FBT (USA) versus IMT (Germany) using naturalistic treatment data. To yield similar subgroups of youth aged 12\u201318 years, inclusion criteria were a percent median BMI (%mBMI) between 70\u201385 and the restrictive AN subtype. Weight gain and hospital days were compared, adjusted further in a multiple linear regression analysis (MLRA) for baseline group differences. Samples differed on baseline %mBMI (FBT [n = 71], 90.5 \u00b1 12.8; IMT [n = 29], 78.3 \u00b1 9.1, p &lt; 0.05). In subgroups with comparable baseline %mBMI, the weekly weight gain over 6 months was similar (FBT [n = 21]: 0.35 \u00b1 0.18 kg\/week; IMT [n = 20]: 0.30 \u00b1 0.18, p = 0.390, p = 0.166 after MLRA), but achieved fewer hospital days in FBT (FBT [n = 7]: 4 \u00b1 6 days, IMT [n = 20]: 121 \u00b1 42 days, p &lt; 0.0001 before and after MLRA). FBT may be effective for a subgroup of adolescents with AN currently receiving IMT, but head-to-head studies in the same healthcare system are needed.<\/jats:p>","DOI":"10.3390\/nu14071396","type":"journal-article","created":{"date-parts":[[2022,3,27]],"date-time":"2022-03-27T21:29:36Z","timestamp":1648416576000},"page":"1396","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The Impact of Inpatient Multimodal Treatment or Family-Based Treatment on Six-Month Weight Outcomes in Youth with Anorexia Nervosa: A Naturalistic, Cross-Continental Comparison"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9362-4108","authenticated-orcid":false,"given":"Janine","family":"Nadler","sequence":"first","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Charit\u00e9 University Hospital Berlin, Augustenburger Platz 1, 13353 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7254-5646","authenticated-orcid":false,"given":"Christoph U.","family":"Correll","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Charit\u00e9 University Hospital Berlin, Augustenburger Platz 1, 13353 Berlin, Germany"},{"name":"Department of Psychiatry Research, The Zucker Hillside Hospital, 75-59 263rd Street, Glen Oaks, NY 11004, USA"},{"name":"Department of Psychiatry and Molecular Medicine, The Zucker School of Medicine at Hofstra\/Northwell, Hempstead, NY 11549, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7293-9496","authenticated-orcid":false,"given":"Daniel","family":"Le Grange","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, University of California, 401 Parnassus Ave., San Francisco, CA 94143, USA"},{"name":"Department of Psychiatry and Behavioral Neurosciences, The University of Chicago as Emeritus, Chicago, IL 60637, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin C.","family":"Accurso","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, University of California, 401 Parnassus Ave., San Francisco, CA 94143, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verena","family":"Haas","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Charit\u00e9 University Hospital Berlin, Augustenburger Platz 1, 13353 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Golden, N.H., Schneider, M., and Wood, C. 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