{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T14:16:56Z","timestamp":1788617816003,"version":"build-2803163510"},"reference-count":31,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T00:00:00Z","timestamp":1653004800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002332","name":"Innovation Centre of Semmelweis University","doi-asserted-by":"publisher","award":["STIA-KFI-2021-TK2151VMKL"],"award-info":[{"award-number":["STIA-KFI-2021-TK2151VMKL"]}],"id":[{"id":"10.13039\/501100002332","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002332","name":"Innovation Centre of Semmelweis University","doi-asserted-by":"publisher","award":["TKP2021-EGA\/TKP2021-NVA\/TKP2021-NKTA"],"award-info":[{"award-number":["TKP2021-EGA\/TKP2021-NVA\/TKP2021-NKTA"]}],"id":[{"id":"10.13039\/501100002332","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ministry of Innovation and Technology of Hungary from the National Research, Development and Innovation Fund","award":["STIA-KFI-2021-TK2151VMKL"],"award-info":[{"award-number":["STIA-KFI-2021-TK2151VMKL"]}]},{"name":"Ministry of Innovation and Technology of Hungary from the National Research, Development and Innovation Fund","award":["TKP2021-EGA\/TKP2021-NVA\/TKP2021-NKTA"],"award-info":[{"award-number":["TKP2021-EGA\/TKP2021-NVA\/TKP2021-NKTA"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Although excessive alcohol consumption is by far the most frequent cause of recurrent acute pancreatitis (AP) cases, specific therapy is still not well established to prevent recurrence. Generally, psychological therapy (e.g., brief intervention (BI)) is the cornerstone of cessation programs; however, it is not yet widely used in everyday practice. We conducted a post-hoc analysis of a prospectively collected database. Patients suffering from alcohol-induced AP between 2016 and 2021 received 30 min BI by a physician. Patient-reported alcohol consumption, serum gamma-glutamyl-transferase (GGT) level, and mean corpuscular volume (MCV) of red blood cells were collected on admission and at the 1-month follow-up visit to monitor patients\u2019 drinking habits. Ninety-nine patients with alcohol-induced AP were enrolled in the study (mean age: 50 \u00b1 11, 89% male). A significant decrease was detected both in mean GGT value (294 \u00b1 251 U\/L vs. 103 \u00b1 113 U\/L, p &lt; 0.001) and in MCV level (93.7 \u00b1 5.3 U\/L vs. 92.1 \u00b1 5.1 U\/L, p &lt; 0.001) in patients with elevated on-admission GGT levels. Notably, 79% of the patients (78\/99) reported alcohol abstinence at the 1-month control visit. Brief intervention is an effective tool to reduce alcohol consumption and to prevent recurrent AP. Longitudinal randomized clinical studies are needed to identify the adequate structure and frequency of BIs in alcohol-induced AP.<\/jats:p>","DOI":"10.3390\/nu14102131","type":"journal-article","created":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T04:27:22Z","timestamp":1653020842000},"page":"2131","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["In-Hospital Patient Education Markedly Reduces Alcohol Consumption after Alcohol-Induced Acute Pancreatitis"],"prefix":"10.3390","volume":"14","author":[{"given":"Rita","family":"Nagy","sequence":"first","affiliation":[{"name":"Centre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary"},{"name":"Institute for Translational Medicine, Szent\u00e1gothai Research Centre, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"},{"name":"Heim P\u00e1l National Pediatric Institute, 1089 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5848-2506","authenticated-orcid":false,"given":"Klementina","family":"Ocskay","sequence":"additional","affiliation":[{"name":"Centre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary"},{"name":"Institute for Translational Medicine, Szent\u00e1gothai Research Centre, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8229-6340","authenticated-orcid":false,"given":"Alex","family":"V\u00e1radi","sequence":"additional","affiliation":[{"name":"Institute for Translational Medicine, Szent\u00e1gothai Research Centre, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1ria","family":"Papp","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, University of Debrecen, 4032 Debrecen, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsuzsanna","family":"Vit\u00e1lis","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, University of Debrecen, 4032 Debrecen, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7767-4319","authenticated-orcid":false,"given":"Ferenc","family":"Izb\u00e9ki","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Szent Gy\u00f6rgy University Teaching Hospital of County Fej\u00e9r, 8000 Sz\u00e9kesfeh\u00e9rv\u00e1r, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eszter","family":"Boros","sequence":"additional","affiliation":[{"name":"Institute for Translational Medicine, Szent\u00e1gothai Research Centre, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"},{"name":"Department of Internal Medicine, Szent Gy\u00f6rgy University Teaching Hospital of County Fej\u00e9r, 8000 Sz\u00e9kesfeh\u00e9rv\u00e1r, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e1szl\u00f3","family":"Gajd\u00e1n","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Szent Gy\u00f6rgy University Teaching Hospital of County Fej\u00e9r, 8000 Sz\u00e9kesfeh\u00e9rv\u00e1r, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Szentesi","sequence":"additional","affiliation":[{"name":"Centre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary"},{"name":"Centre for Translational Medicine, Department of Medicine, University of Szeged, 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e1lint","family":"Er\u0151ss","sequence":"additional","affiliation":[{"name":"Centre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary"},{"name":"Institute for Translational Medicine, Szent\u00e1gothai Research Centre, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"},{"name":"Division of Pancreatic Diseases, Heart and Vascular Center, Semmelweis University, 1082 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter Jen\u0151","family":"Hegyi","sequence":"additional","affiliation":[{"name":"Institute for Translational Medicine, Szent\u00e1gothai Research Centre, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"},{"name":"Division of Pancreatic Diseases, Heart and Vascular Center, Semmelweis University, 1082 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2217-7686","authenticated-orcid":false,"given":"\u00c1ron","family":"Vincze","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, First Department of Medicine, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3941-4871","authenticated-orcid":false,"given":"Judit","family":"Bajor","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, First Department of Medicine, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5086-9455","authenticated-orcid":false,"given":"Patricia","family":"Sarlos","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, First Department of Medicine, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5322-4425","authenticated-orcid":false,"given":"Alexandra","family":"Mik\u00f3","sequence":"additional","affiliation":[{"name":"Institute for Translational Medicine, Szent\u00e1gothai Research Centre, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"},{"name":"Department of Medical Genetics, Medical School, University of P\u00e9cs, 7623 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2213-4865","authenticated-orcid":false,"given":"Katalin","family":"M\u00e1rta","sequence":"additional","affiliation":[{"name":"Centre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary"},{"name":"Division of Pancreatic Diseases, Heart and Vascular Center, Semmelweis University, 1082 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0499-6004","authenticated-orcid":false,"given":"D\u00e1niel","family":"P\u00e9csi","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, First Department of Medicine, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"P\u00e1rniczky","sequence":"additional","affiliation":[{"name":"Centre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary"},{"name":"Institute for Translational Medicine, Szent\u00e1gothai Research Centre, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"},{"name":"Heim P\u00e1l National Pediatric Institute, 1089 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"Hegyi","sequence":"additional","affiliation":[{"name":"Centre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary"},{"name":"Institute for Translational Medicine, Szent\u00e1gothai Research Centre, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"},{"name":"Division of Pancreatic Diseases, Heart and Vascular Center, Semmelweis University, 1082 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,5,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1053\/j.gastro.2018.08.063","article-title":"Burden and cost of gastrointestinal, liver, and pancreatic diseases in the united states: Update 2018","volume":"156","author":"Peery","year":"2019","journal-title":"Gastroenterology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s00534-005-1047-3","article-title":"JPN Guidelines for the management of acute pancreatitis: Epidemiology, etiology, natural history, and outcome predictors in acute pancreatitis","volume":"13","author":"Sekimoto","year":"2006","journal-title":"J. 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