{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T00:41:24Z","timestamp":1760229684184,"version":"build-2065373602"},"reference-count":10,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T00:00:00Z","timestamp":1655942400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Vitamin K and its derivatives represent a complex of fat-soluble vitamins, playing a major role in the regulation of a large number of physiologic processes required for optimal homeostasis [...]<\/jats:p>","DOI":"10.3390\/nu14132595","type":"journal-article","created":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T22:43:00Z","timestamp":1656024180000},"page":"2595","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Editorial for the Special Issue \u201cVitamin K in Chronic Disease and Human Health\u201d"],"prefix":"10.3390","volume":"14","author":[{"given":"Evangelia","family":"Dounousi","sequence":"first","affiliation":[{"name":"Department of Nephrology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7564-2724","authenticated-orcid":false,"given":"Vasillios","family":"Liakopoulos","sequence":"additional","affiliation":[{"name":"Section of Nephrology and Hypertension, First Department of Medicine, AHEPA Hospital, Medical School, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.nut.2006.05.003","article-title":"Pleiotropic actions of vitamin K: Protector of bone health and beyond?","volume":"22","author":"Kaneki","year":"2006","journal-title":"Nutrition"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1038\/135652b0","article-title":"The antihemorrhagic vitamin of the chick. Occurrence and chemical nature","volume":"135","author":"Dam","year":"1935","journal-title":"Nature"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Halder, M., Petsophonsakul, P., Akbulut, A.C., Pavlic, A., Bohan, F., Anderson, E., Maresz, K., Kramann, R., and Schurgers, L. (2019). Vitamin K: Double Bonds beyond Coagulation Insights into Differences between Vitamin K1 and K2 in Health and Disease. Int. J. Mol. Sci., 20.","DOI":"10.3390\/ijms20040896"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1182\/blood.V93.6.1798.406k22_1798_1808","article-title":"Vitamin K-dependent biosynthesis of gamma-carboxyglutamic acid","volume":"93","author":"Furie","year":"1999","journal-title":"Blood"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1053\/j.ackd.2019.10.005","article-title":"The Role of Vitamin K in Vascular Calcification","volume":"26","author":"Cozzolino","year":"2019","journal-title":"Adv. Chronic Kidney Dis."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Dahlberg, S., Sch\u00f6tt, U., Eriksson, E., Tahirsylaj, Y., Schurgers, L., and Kander, T. (2021). Intravenous Vitamin K1 for the Correction of Prolonged Prothrombin Times in Non-Bleeding Critically Ill Patients: A Prospective Observational Study. Nutrients, 13.","DOI":"10.3390\/nu13082580"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Sch\u00f6tt, U., Augustsson, C., Lilover, L., Nilsson, C.U., Walther-Sturesson, L., and Kander, T. (2021). Vitamin K Effects on Gas6 and Soluble Axl Receptors in Intensive Care Patients: An Observational Screening Study. Nutrients, 13.","DOI":"10.3390\/nu13114101"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Rapp, N., Brandenburg, V.M., Kaesler, N., Bakker, S.J.L., St\u00f6hr, R., Schuh, A., Evenepoel, P., and Schurgers, L.J. (2021). Hepatic and Vascular Vitamin K Status in Patients with High Cardiovascular Risk. Nutrients, 13.","DOI":"10.3390\/nu13103490"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Roumeliotis, S., Duni, A., Vaios, V., Kitsos, A., Liakopoulos, V., and Dounousi, E. (2022). Vitamin K Supplementation for Prevention of Vascular Calcification in Chronic Kidney Disease Patients: Are We There Yet?. Nutrients, 14.","DOI":"10.3390\/nu14050925"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Kremer, D., Groothof, D., Keyzer, C.A., Eelderink, C., Knobbe, T.J., Post, A., van Londen, M., Eisenga, M.F., TransplantLines Investigators, and Schurgers, L.J. (2021). Kidney Function-Dependence of Vitamin K-Status Parameters: Results from the TransplantLines Biobank and Cohort Studies. Nutrients, 13.","DOI":"10.3390\/nu13093069"}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/14\/13\/2595\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:38:13Z","timestamp":1760139493000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/14\/13\/2595"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,23]]},"references-count":10,"journal-issue":{"issue":"13","published-online":{"date-parts":[[2022,7]]}},"alternative-id":["nu14132595"],"URL":"https:\/\/doi.org\/10.3390\/nu14132595","relation":{},"ISSN":["2072-6643"],"issn-type":[{"type":"electronic","value":"2072-6643"}],"subject":[],"published":{"date-parts":[[2022,6,23]]}}}