{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:39:35Z","timestamp":1792802375764,"version":"4.5.0"},"reference-count":210,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2022,6,26]],"date-time":"2022-06-26T00:00:00Z","timestamp":1656201600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Throughout history, malnutrition and deficiency diseases have been a problem for our planet\u2019s population. A balanced diet significantly influences everyone\u2019s health, and fiber intake appears to play a more important role than previously thought. The natural dietary fibers are a category of carbohydrates in the constitution of plants that are not completely digested in the human intestine. High-fiber foods, such as fruits, vegetables and whole grains, have consistently been highly beneficial to health and effectively reduced the risk of disease. Although the mode of action of dietary fiber in the consumer body is not fully understood, nutritionists and health professionals unanimously recognize the therapeutic benefits. This paper presents the fiber consumption in different countries, the metabolism of fiber and the range of health benefits associated with fiber intake. In addition, the influence of fiber intake on the intestinal microbiome, metabolic diseases (obesity and diabetes), neurological aspects, cardiovascular diseases, autoimmune diseases and cancer prevention are discussed. Finally, dietary restrictions and excess fiber are addressed, which can cause episodes of diarrhea and dehydration and increase the likelihood of bloating and flatulence or even bowel obstruction. However, extensive studies are needed regarding the composition and required amount of fiber in relation to the metabolism of saprotrophic microorganisms from the enteral level and the benefits of the various pathologies with which they can be correlated.<\/jats:p>","DOI":"10.3390\/nu14132641","type":"journal-article","created":{"date-parts":[[2022,6,26]],"date-time":"2022-06-26T21:01:41Z","timestamp":1656277301000},"page":"2641","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":240,"title":["Therapeutic Benefits and Dietary Restrictions of Fiber Intake: A State of the Art Review"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4967-7146","authenticated-orcid":false,"given":"Corina-Bianca","family":"Ioni\u021b\u0103-M\u00eendrican","sequence":"first","affiliation":[{"name":"Department of Toxicology, Faculty of Pharmacy, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 3-6, Traian Vuia Street, Sector 2, 020945 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Ziani","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory and Food Safety, Faculty of Pharmacy, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 3-6, Traian Vuia Street, Sector 2, 020956 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8448-5054","authenticated-orcid":false,"given":"Magdalena","family":"Mititelu","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory and Food Safety, Faculty of Pharmacy, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 3-6, Traian Vuia Street, Sector 2, 020956 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7051-4136","authenticated-orcid":false,"given":"Eliza","family":"Oprea","sequence":"additional","affiliation":[{"name":"Microbiology Department, Faculty of Biology, University of Bucharest, 1-3 Portocalilor Way, 060101 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sorinel Marius","family":"Neac\u0219u","sequence":"additional","affiliation":[{"name":"Professional Farma Line, 116 Republicii Street, 105200 Baicoi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Moro\u0219an","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory and Food Safety, Faculty of Pharmacy, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 3-6, Traian Vuia Street, Sector 2, 020956 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8424-1877","authenticated-orcid":false,"given":"Denisa-Elena","family":"Dumitrescu","sequence":"additional","affiliation":[{"name":"Department of Organic Chemistry, Faculty of Pharmacy, \u201cOvidius\u201d University of Constanta, 6, C\u0103pitan Aviator Al \u0218erb\u0103nescu Street, 900470 Constanta, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian Cosmin","family":"Ro\u0219ca","sequence":"additional","affiliation":[{"name":"Department of Drug Analysis, Biopharmacy and Biological Medicines, Faculty of Pharmacy, \u201cOvidius\u201d University of Constanta, 6, C\u0103pitan Aviator Al \u0218erb\u0103nescu Street, 900470 Constanta, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doina","family":"Dr\u0103g\u0103nescu","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Physics and Informatics, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 6, Traian Vuia Street, 020956 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Negrei","sequence":"additional","affiliation":[{"name":"Department of Toxicology, Faculty of Pharmacy, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 3-6, Traian Vuia Street, Sector 2, 020945 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S1957-2557(15)30169-3","article-title":"Que Conseiller Aux Patients Diab\u00e9tiques de Type 2: Deux Ou Six Prises Alimentaires Quotidiennes?","volume":"9","author":"Hansel","year":"2015","journal-title":"M\u00e9decine Des Mal. 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