{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T02:17:49Z","timestamp":1782181069555,"version":"3.54.5"},"reference-count":39,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2022,6,28]],"date-time":"2022-06-28T00:00:00Z","timestamp":1656374400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Department for the Economy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Limited studies have reported vitamin D status and health outcomes in care home residents, a group at risk of vitamin D deficiency. This study investigated serum 25-hydroxyvitamin D (25-OHD) concentrations in older adults within care homes in Northern Ireland (NI) and its association with musculoskeletal health (ultrasound T-score, muscle strength, Timed Up &amp; Go test (TUG)), bone turnover markers (BTMs), and immune function markers. A total of 87 participants were recruited with mean \u00b1 SD age 83.2 \u00b1 7.9 years. Mean \u00b1 SD serum 25-OHD concentration (n 69) was 49.52 \u00b1 35.58 nmol\/L. Vitamin D deficiency (25-OHD &lt;25 nmol\/L) was observed in 34.8% (n 24) of participants with 17.4% (n 12) classified as insufficient (25-OHD 25\u201350 nmol\/L) and 47.8% (n 33) as sufficient (25-OHD &gt;50 nmol\/L). 25-OHD concentration was not an independent predictor of T-score, muscle strength, TUG, or inflammatory cytokines. After adjusting for covariates, a significant negative association was observed between 25-OHD concentration and the BTMs; osteocalcin (\u03b2 = \u22120.395; p = 0.001), procollagen type 1 N propeptide (P1NP) (\u03b2 = \u22120.320; p = 0.012), and C-terminal telopeptide of type 1 collagen (CTX) (\u03b2 = \u22120.377; p = 0.003). Higher 25-OHD concentration was positively associated with use of vitamin D \u00b1 calcium supplementation (\u03b2 = 0.610; p &lt; 0.001). Vitamin D deficiency and insufficiency were highly prevalent in this sample of care home residents in NI. Higher 25-OHD concentration was associated with greater supplement use and with reduced bone turnover, which in this population is linked with reduced bone loss. These findings emphasize the need for a mandatory vitamin D \u00b1 calcium supplementation policy specific for care home residents.<\/jats:p>","DOI":"10.3390\/nu14132680","type":"journal-article","created":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T01:48:38Z","timestamp":1656467318000},"page":"2680","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Vitamin D and Bone Health of Older Adults within Care Homes: An Observational Study"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0794-1300","authenticated-orcid":false,"given":"Orlagh","family":"Feehan","sequence":"first","affiliation":[{"name":"Nutrition Innovation Centre for Food and Health (NICHE), Ulster University, Coleraine BT52 1SA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1583-8602","authenticated-orcid":false,"given":"David","family":"Armstrong","sequence":"additional","affiliation":[{"name":"Nutrition Innovation Centre for Food and Health (NICHE), Ulster University, Coleraine BT52 1SA, UK"},{"name":"Department of Rheumatology, Altnagelvin Hospital, Western Health and Social Care Trust, Londonderry BT47 6SB, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0479-3314","authenticated-orcid":false,"given":"Pamela","family":"Magee","sequence":"additional","affiliation":[{"name":"Nutrition Innovation Centre for Food and Health (NICHE), Ulster University, Coleraine BT52 1SA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2251-5251","authenticated-orcid":false,"given":"L.","family":"Pourshahidi","sequence":"additional","affiliation":[{"name":"Nutrition Innovation Centre for Food and Health (NICHE), Ulster University, Coleraine BT52 1SA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1633-2873","authenticated-orcid":false,"given":"J.","family":"Strain","sequence":"additional","affiliation":[{"name":"Nutrition Innovation Centre for Food and Health (NICHE), Ulster University, Coleraine BT52 1SA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Beggan","sequence":"additional","affiliation":[{"name":"Nutrition Innovation Centre for Food and Health (NICHE), Ulster University, Coleraine BT52 1SA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5283-2931","authenticated-orcid":false,"given":"Diego","family":"Cobice","sequence":"additional","affiliation":[{"name":"Mass Spectrometry Centre, Biomedical Sciences Research Institute (BMSRI), Ulster University, Coleraine BT52 1SA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1861-3991","authenticated-orcid":false,"given":"Emeir","family":"McSorley","sequence":"additional","affiliation":[{"name":"Nutrition Innovation Centre for Food and Health (NICHE), Ulster University, Coleraine BT52 1SA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.nut.2009.04.022","article-title":"Comparative 25-OH-vitamin D level in institutionalized women older than 65 years from two cities in Spain and Argentina having a similar solar radiation index","volume":"26","author":"Portela","year":"2010","journal-title":"Nutrition"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s12603-011-0361-5","article-title":"Walk on the sunny side of life\u2014Epidemiology of hypovitaminosis D and mental health in elderly nursing home residents","volume":"16","author":"Verhoeven","year":"2011","journal-title":"J. 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