{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:45:41Z","timestamp":1792806341135,"version":"4.5.0"},"reference-count":40,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T00:00:00Z","timestamp":1656460800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Research Foundation of the Region of Southern Denmark","id":[{"id":"https:\/\/ror.org\/0290a6k23","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Health Science Research Foundation of the Region of Zealand"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>(1) Very preterm infants are at increased risk of cognitive deficits, motor impairments, and behavioural problems. Studies have tied insufficient nutrition and growth to an increased risk of neurodevelopmental impairment; (2) Methods: Follow-up study on cognitive and neuropsychological development at 6 years corrected age (CA) in 214 very preterm infants, including 141 breastfed infants randomised to mother\u2019s own milk (MOM) with (F-MOM) or without (U-MOM) fortification and 73 infants fed a preterm formula (PF-group), from shortly before discharge to 4 months CA. Infants with serious congenital anomalies or major neonatal morbidities were excluded prior to intervention. The Wechsler Intelligence Scale for Children IV was used for cognitive testing, and the children\u2019s parents completed the Five to Fifteen Questionnaire (FTF); (3) Results: Post-discharge fortification of MOM did not improve either full-scale intelligence quotient (FSIQ) with a median of 104 vs. 105.5 (p = 0.29), subdomain scores, or any domain score on the FTF questionnaire. Compared to the PF group, the MOM group had significantly better verbal comprehension score with a median of 110 vs. 106 (p = 0.03) and significantly better motor skills scores on the FTF questionnaire (p = 0.01); (4) Conclusions: The study supports breastfeeding without fortification as post-discharge nutrition in very preterm infants, and it seems superior to preterm formula.<\/jats:p>","DOI":"10.3390\/nu14132709","type":"journal-article","created":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T22:43:28Z","timestamp":1656542608000},"page":"2709","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["IQ Was Not Improved by Post-Discharge Fortification of Breastmilk in Very Preterm Infants"],"prefix":"10.3390","volume":"14","author":[{"given":"Anja","family":"Klamer","sequence":"first","affiliation":[{"name":"Hans Christian Andersen Children\u2019s Hospital, Odense University Hospital, 5000 Odense, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Line H.","family":"Toftlund","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Holbaek Hospital, 4300 Holbaek, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristjan","family":"Grimsson","sequence":"additional","affiliation":[{"name":"Hans Christian Andersen Children\u2019s Hospital, Odense University Hospital, 5000 Odense, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Halken","sequence":"additional","affiliation":[{"name":"Hans Christian Andersen Children\u2019s Hospital, Odense University Hospital, 5000 Odense, Denmark"},{"name":"Faculty of Health Sciences, University of Southern Denmark, 5000 Odense, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gitte","family":"Zachariassen","sequence":"additional","affiliation":[{"name":"Hans Christian Andersen Children\u2019s Hospital, Odense University Hospital, 5000 Odense, Denmark"},{"name":"Faculty of Health Sciences, University of Southern Denmark, 5000 Odense, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1001\/jamapediatrics.2017.5323","article-title":"Cognitive Outcomes of Children Born Extremely or Very Preterm Since the 1990s and Associated Risk Factors: A Meta-analysis and Meta-regression","volume":"172","author":"Twilhaar","year":"2018","journal-title":"JAMA Pediatr."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1203\/PDR.0b013e318212faa0","article-title":"Preterm birth and childhood psychiatric disorders","volume":"69","author":"Johnson","year":"2011","journal-title":"Pediatr. 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