{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T07:07:08Z","timestamp":1792220828232,"version":"4.4.0"},"reference-count":151,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2022,7,20]],"date-time":"2022-07-20T00:00:00Z","timestamp":1658275200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Psoriasis is a chronic inflammatory skin disease with autoimmune pathogenic characteristics and is caused by chronic inflammation, which results in uncontrolled keratinocyte growth and defective differentiation. The link between the gut microbiota and immune system regulation opened a novel angle to understand the pathogenesis of many chronic multifactorial diseases, including psoriasis. Current evidence suggests that modulation of the gut microbiota, both through dietary approaches and through supplementation with probiotics and prebiotics, could represent a novel therapeutic approach. The present work aims to highlight the latest scientific evidence regarding the microbiome alterations of psoriatic patients, as well as state of the art insights in terms of microbiome-targeted therapies as promising preventive and therapeutic tools for psoriasis.<\/jats:p>","DOI":"10.3390\/nu14142970","type":"journal-article","created":{"date-parts":[[2022,7,21]],"date-time":"2022-07-21T03:34:40Z","timestamp":1658374480000},"page":"2970","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":111,"title":["Gut Microbiota in Psoriasis"],"prefix":"10.3390","volume":"14","author":[{"given":"Mihaela Cristina","family":"Buha\u0219","sequence":"first","affiliation":[{"name":"Department of Dermatology, \u201cIuliu Hatieganu\u201d University of Medicine and Pharmacy, 400423 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura Ioana","family":"Gavrila\u0219","sequence":"additional","affiliation":[{"name":"Department of Bromatology, Hygiene, Nutrition, \u201cIuliu Hatieganu\u201d University of Medicine and Pharmacy, 23 Marinescu Street, 400337 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rare\u0219","family":"Candrea","sequence":"additional","affiliation":[{"name":"Bachelor Program in Nutrition and Dietetics, \u201cIuliu Hatieganu\u201d University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6327-6608","authenticated-orcid":false,"given":"Adrian","family":"C\u0103tinean","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine\/Gastroenterology, Faculty of Medicine, \u201cIuliu Hatieganu\u201d University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5848-8457","authenticated-orcid":false,"given":"Andrei","family":"Mocan","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Botany, \u201cIuliu Hatieganu\u201d University of Medicine and Pharmacy, 23 Marinescu Street, 400337 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5029-5060","authenticated-orcid":false,"given":"Doina","family":"Miere","sequence":"additional","affiliation":[{"name":"Department of Bromatology, Hygiene, Nutrition, \u201cIuliu Hatieganu\u201d University of Medicine and Pharmacy, 23 Marinescu Street, 400337 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandru","family":"T\u0103taru","sequence":"additional","affiliation":[{"name":"Department of Dermatology, \u201cIuliu Hatieganu\u201d University of Medicine and Pharmacy, 400423 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Rendon, A., and Sch\u00e4kel, K. 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