{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T13:30:37Z","timestamp":1785504637104,"version":"3.56.0"},"reference-count":35,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T00:00:00Z","timestamp":1661817600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Nutrition can play an important role in the treatment of chronic wounds such as diabetic foot ulcers (DFUs); however, diet therapy is not currently part of the standard care for DFUs. There are numerous controversies about dietary recommendations, especially regarding calories and macronutrients, for overweight and obese patients with DFUs. This study examined the effects of nutrition education and supplementation on body composition in overweight and obese patients with DFUs. Twenty-nine patients with DFUs between the ages of 30 and 70 years were randomly assigned to either the treatment group (nutritional supplements, diet education, and standard care) or the control group (standard care). At baseline, the mean body mass index (BMI) was 33.5 kg\/m2 for the treatment group and 34.1 kg\/m2 for the control group. HbA1c decreased in both groups, with no significant difference between the groups. On average, patients in the treatment group lost less lean body mass and gained less fat than the control group ((3.8 kg vs. 4.9 kg) and (0.9 kg vs. 3.6 kg), respectively). While the interaction between group and time did not reach statistical significance for any of the study variables after adjustments for confounding variables, the observed changes are clinically relevant.<\/jats:p>","DOI":"10.3390\/nu14173564","type":"journal-article","created":{"date-parts":[[2022,8,31]],"date-time":"2022-08-31T00:13:56Z","timestamp":1661904836000},"page":"3564","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Effects of Nutrition Intervention on Blood Glucose, Body Composition, and Phase Angle in Obese and Overweight Patients with Diabetic Foot Ulcers"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7780-3771","authenticated-orcid":false,"given":"Raedeh","family":"Basiri","sequence":"first","affiliation":[{"name":"Department of Nutrition and Food Studies, George Mason University, Fairfax, VA 22030, USA"},{"name":"Institute for Biohealth Innovation, George Mason University, Fairfax, VA 22030, USA"},{"name":"Department of Nutrition and Integrative Physiology, Florida State University, Tallahassee, FL 32306, USA"},{"name":"Center for Advancing Exercise and Nutrition Research on Aging, Florida State University, Tallahassee, FL 32306, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria T.","family":"Spicer","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Integrative Physiology, Florida State University, Tallahassee, FL 32306, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4976-6942","authenticated-orcid":false,"given":"Thomas","family":"Ledermann","sequence":"additional","affiliation":[{"name":"Department of Family and Child Sciences, Florida State University, Tallahassee, FL 32306, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1358-0238","authenticated-orcid":false,"given":"Bahram H.","family":"Arjmandi","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Integrative Physiology, Florida State University, Tallahassee, FL 32306, USA"},{"name":"Center for Advancing Exercise and Nutrition Research on Aging, Florida State University, Tallahassee, FL 32306, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.2522\/ptj.20080020","article-title":"Epidemiology of Diabetes and Diabetes-Related Complications","volume":"88","author":"Deshpande","year":"2008","journal-title":"Phys Ther"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"651","DOI":"10.2337\/dc13-2176","article-title":"Burden of Diabetic Foot Ulcers for Medicare and Private Insurers","volume":"37","author":"Rice","year":"2014","journal-title":"Diabetes Care"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1177\/1534734619900415","article-title":"Quality of Life in Diabetic Foot Ulcer: Associated Factors and the Impact of Anxiety\/Depression and Adherence to Self-Care","volume":"19","author":"Polikandrioti","year":"2020","journal-title":"Int. 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