{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:41:59Z","timestamp":1777480919551,"version":"3.51.4"},"reference-count":44,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2022,10,2]],"date-time":"2022-10-02T00:00:00Z","timestamp":1664668800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Medical University of Silesia in Katowice","award":["PCN-1-111\/N\/0\/O"],"award-info":[{"award-number":["PCN-1-111\/N\/0\/O"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Over-nutrition with cafeteria diet leads to glycemic control failure and subsequent obesity. Bariatric surgery remains the ultimate treatment option, and when complemented with specific dietary protocol, it may mitigate the effects of oxidative stress induced by a cafeteria diet. The study measured antioxidant marker activity: superoxidase dismutase (SOD) and ceruloplasmin (CER), total antioxidant capacity (TAC), and lipid peroxidation marker concentrations: lipofuscin (LS) and malondialdehyde (MDA), in the plasma of 56 Sprague-Dawley rats fed with a cafeteria (HFS) or a control (CD) diet and subjected to duodenojejunal omega switch (DJOS) or control (SHAM) surgery. The diet change after the surgery (CD\/HFS or HFS\/CD) strongly influenced SOD activity in DJOS- and SHAM-operated rats, but SOD activity was always higher in SHAM-operated rats. Every dietary protocol used in the study increased CER activity, except for the CD\/CD combination. Cafeteria diet consumed before or after either of surgeries led to decrease in TAC levels. DJOS and no change in diet reduced MDA levels. DJOS reduced LS levels, but its beneficial effect was deteriorated by selected dietary protocols. The cafeteria diet negatively affected the positive impact of DJOS surgery, but SOD, CER, MDA, and LS were significantly lower in rats that underwent DJOS, suggesting that eight weeks of dietary treatment before and after the surgery did not totally dilapidate the effects of the bariatric treatment.<\/jats:p>","DOI":"10.3390\/nu14194097","type":"journal-article","created":{"date-parts":[[2022,10,10]],"date-time":"2022-10-10T01:21:07Z","timestamp":1665364867000},"page":"4097","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Duodenojejunal Omega Switch Surgery Reduces Oxidative Stress Induced by Cafeteria Diet in Sprague-Dawley Rats"],"prefix":"10.3390","volume":"14","author":[{"given":"Jakub","family":"Poloczek","sequence":"first","affiliation":[{"name":"Department of Rehabilitation, 3rd Specialist Hospital in Rybnik, Energetyk\u00f3w 46 Street, 44-200 Rybnik, Poland"},{"name":"Department of Internal Medicine, Diabetology and Nephrology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Poniatowskiego 15 Street, 40-055 Katowice, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9397-1089","authenticated-orcid":false,"given":"Wojciech","family":"Kazura","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Jordana Street 19, 40-055 Katowice, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0111-438X","authenticated-orcid":false,"given":"El\u017cbieta","family":"Che\u0142mecka","sequence":"additional","affiliation":[{"name":"Department of Statistics, Department of Instrumental Analysis, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Poniatowskiego 15 Street, 40-055 Katowice, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1809-9531","authenticated-orcid":false,"given":"Katarzyna","family":"Michalczyk","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Jordana Street 19, 40-055 Katowice, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerzy","family":"Jochem","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Jordana Street 19, 40-055 Katowice, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janusz","family":"Gumprecht","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Diabetology and Nephrology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Poniatowskiego 15 Street, 40-055 Katowice, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominika","family":"Stygar","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Jordana Street 19, 40-055 Katowice, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1080\/1028415X.2017.1380892","article-title":"The metabolic and neuroinflammatory changes induced by consuming a cafeteria diet are age-dependent","volume":"22","author":"Teixeira","year":"2019","journal-title":"Nutr. Neurosci."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.neubiorev.2020.11.003","article-title":"The cafeteria diet: A standardized protocol and its effects on behavior","volume":"122","author":"Lalanza","year":"2021","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_3","first-page":"153","article-title":"Palatable western-style cafeteria diet as a reliable method for modeling diet-induced obesity in rodents","volume":"2019","author":"Leigh","year":"2019","journal-title":"J. Vis. Exp."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.diabres.2007.03.006","article-title":"Lifestyle factors and incident metabolic syndrome. The Troms\u00f8 Study 1979\u20132001","volume":"78","author":"Wilsgaard","year":"2007","journal-title":"Diabetes Res. Clin. Pract."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1038\/oby.2011.18","article-title":"Cafeteria diet is a robust model of human metabolic syndrome with liver and adipose inflammation: Comparison to high-fat diet","volume":"19","author":"Sampey","year":"2011","journal-title":"Obesity"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1093\/ajcn.81.2.341","article-title":"Origins and evolution of the Western diet: Health implications for the 21st century","volume":"81","author":"Cordain","year":"2005","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1007\/s11695-017-2883-3","article-title":"The effects of duodenojejunal omega switch in combination with high-fat diet and control diet on incretins, body weight, and glucose tolerance in Sprague-Dawley rats","volume":"28","author":"Stygar","year":"2018","journal-title":"Obes. Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"4005","DOI":"10.1210\/en.2011-1691","article-title":"Inflammation as a sensor of metabolic stress in obesity and type 2 diabetes","volume":"152","author":"Donath","year":"2011","journal-title":"Endocrinology"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1172\/JCI25102","article-title":"Inflammation, stress, and diabetes","volume":"115","author":"Wellen","year":"2005","journal-title":"J. Clin. Investig."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"5527107","DOI":"10.1155\/2021\/5527107","article-title":"Effects of bariatric surgeries on fetuin-A, selenoprotein P, angiopoietin-like protein 6, and fibroblast growth factor 21 concentration","volume":"2021","author":"Poloczek","year":"2021","journal-title":"J. Diabetes Res."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s12192-019-00976-2","article-title":"The influence of high-fat, high-sugar diet and bariatric surgery on HSP70 and HSP90 plasma and liver concentrations in diet-induced obese rats","volume":"24","author":"Stygar","year":"2019","journal-title":"Cell Stress Chaperones"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Coudriet, G.M., Delmastro-Greenwood, M.M., Previte, D.M., Marr\u00e9, M.L., O'Connor, E.C., Novak, E.A., Vincent, G., Mollen, K.P., Lee, S., and Dong, H.H. (2017). Treatment with a catalytic superoxide dismutase (SOD) mimetic improves liver steatosis, insulin sensitivity, and inflammation in obesity-induced type 2 diabetes. Antioxidants, 6.","DOI":"10.3390\/antiox6040085"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1055\/s-2007-1018928","article-title":"The effect of diabetes on the activities of the peroxide metabolism enzymes","volume":"14","author":"Matkovics","year":"1982","journal-title":"Horm. Metab. Res."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.1161\/CIRCRESAHA.116.307591","article-title":"Treatment of obesity: Weight loss and bariatric surgery","volume":"118","author":"Wolfe","year":"2016","journal-title":"Circ. Res."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1146\/annurev.med.051308.105148","article-title":"Metabolic surgery to treat type 2 diabetes: Clinical outcomes and mechanisms of action","volume":"61","author":"Rubino","year":"2010","journal-title":"Ann. Rev. Med."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"2724","DOI":"10.1007\/s11695-017-2866-4","article-title":"The long-term effects of bariatric surgery on type 2 diabetes remission, microvascular and macrovascular complications, and mortality: A systematic review and meta-analysis","volume":"27","author":"Sheng","year":"2017","journal-title":"Obes. Surg."},{"key":"ref_17","unstructured":"Russell, W.M., and Burch, R.L. (1959). The Principles of Humane Experimental Technique, Methuen."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"2151429","DOI":"10.1155\/2018\/2151429","article-title":"Changes of plasma FABP4, CRP, leptin, and chemerin levels in relation to different dietary patterns and duodenal-jejunal omega switch surgery in Sprague-Dawley rats","volume":"2018","author":"Stygar","year":"2018","journal-title":"Oxid. Med. Cell. Longev."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J. Biol. Chem."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/0003-2697(84)90467-6","article-title":"Reevaluation of assay methods and establishment of kit for superoxide dismutase activity","volume":"142","author":"Oyanagui","year":"1984","journal-title":"Anal. Biochem."},{"key":"ref_21","unstructured":"Richterich, R. (1971). Clinical Chemistry, PZWL. (In Polish)."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.clinbiochem.2003.11.015","article-title":"A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation","volume":"37","author":"Erel","year":"2004","journal-title":"Clin. Biochem."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohkawa","year":"1979","journal-title":"Anal. Biochem."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/0005-2760(85)90156-0","article-title":"Fluorescent substances in mouse and human sera as a parameter of in vivo lipid peroxidation","volume":"834","author":"Tsuchida","year":"1985","journal-title":"Biochim. Biophys. Acta"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1016\/j.freeradbiomed.2010.12.005","article-title":"Oxidative stress and the etiology of insulin resistance and type 2 diabetes","volume":"51","author":"Henriksen","year":"2011","journal-title":"Free Radic. Biol. Med."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1242\/jeb.048041","article-title":"The physiological regulation of glucose flux into muscle in vivo","volume":"214","author":"Wasserman","year":"2011","journal-title":"J. Exp. Biol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"7","DOI":"10.5402\/2012\/957283","article-title":"Amelioration of obesity, glucose intolerance, and oxidative stress in high-fat diet and low-dose streptozotocin-induced diabetic rats by combination consisting of curcumin with piperine and quercetin","volume":"2012","author":"Kaur","year":"2012","journal-title":"ISRN Pharmacol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1186\/1758-5996-6-130","article-title":"Metabolic and oxidative stress markers in Wistar rats after 2 months on a high-fat diet","volume":"6","author":"Auberval","year":"2014","journal-title":"Diabetol. Metab. Syndr."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Poloczek, J., Tarnawska, M., Che\u0142mecka, E., \u0141aszczyca, P., Gumprecht, J., and Stygar, D. (2021). High fat, high sugar Diet and DJOS bariatric surgery influence plasma levels of fetuin-B, growth differentiation factor-15, and pentraxin 3 in diet-induced obese Sprague-Dawley rats. Nutrients, 13.","DOI":"10.3390\/nu13103632"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Ulla, A., Alam, M.A., Sikder, B., Sumi, F.A., Rahman, M.M., Habib, Z.F., Mohammed, M.K., Subhan, N., Hossain, H., and Reza, H.M. (2017). Supplementation of Syzygium cumini seed powder prevented obesity, glucose intolerance, hyperlipidemia and oxidative stress in high carbohydrate high fat diet induced obese rats. BMC Complement. Altern. Med., 17.","DOI":"10.1186\/s12906-017-1799-8"},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Skrzep-Poloczek, B., Poloczek, J., Che\u0142mecka, E., Dulska, A., Romuk, E., Idzik, M., Kazura, W., Nabrdalik, K., Gumprecht, J., and Jochem, J. (2020). The oxidative stress markers in the erythrocytes and heart muscle of obese rats: Relate to a high-fat diet but not to DJOS bariatric surgery. Antioxidants, 9.","DOI":"10.3390\/antiox9020183"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/0076-6879(88)63042-4","article-title":"Ceruloplasmin","volume":"163","author":"Arnaud","year":"1988","journal-title":"Meth. Enzymol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.numecd.2006.05.007","article-title":"The implication of obesity on total antioxidant capacity in apparently healthy men and women: The ATTICA study","volume":"17","author":"Chrysohoou","year":"2007","journal-title":"Nutr. Met. Cardiovasc. Dis."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Arner, E., Forrest, A.R., Ehrlund, A., Mejhert, N., Itoh, M., Kawaji, H., Lassmann, T., Laurencikiene, J., Ryd\u00e9n, M., and Arner, P. (2014). Ceruloplasmin is a novel adipokine which is overexpressed in adipose tissue of obese subjects and in obesity-associated cancer cells. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0080274"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1093\/jn\/116.8.1432","article-title":"Influence of genetic obesity on tissue concentrations of zinc, copper, manganese, and iron in mice","volume":"116","author":"Kennedy","year":"1986","journal-title":"J. Nutr."},{"key":"ref_36","first-page":"277","article-title":"Distribution of copper among components of human serum","volume":"75","author":"Wirth","year":"1985","journal-title":"J. Natl. Cancer Inst."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1038\/ijo.2011.159","article-title":"Incidence and prevalence of copper deficiency following Roux-en-Y gastric bypass surgery","volume":"36","author":"Broderius","year":"2012","journal-title":"Int. J. Obes."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1179\/135100004225004814","article-title":"Understanding the association between dietary antioxidants, redox status and disease: Is the total antioxidant capacity the right tool?","volume":"9","author":"Serafini","year":"2013","journal-title":"Redox Rep."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.bbagen.2013.06.030","article-title":"In vitro measurements and interpretation of total antioxidant capacity","volume":"1840","author":"Fraga","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"4861","DOI":"10.1039\/C9FO00651F","article-title":"Acute treatment with Mangifera indica L. leaf extract attenuates liver inflammation in rats fed a cafeteria diet","volume":"10","author":"Toledo","year":"2019","journal-title":"Food Funct."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1196\/annals.1297.015","article-title":"Aging of cardiac myocytes in culture: Oxidative stress, lipofuscin accumulation, and mitochondrial turnover","volume":"1019","author":"Terman","year":"2004","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_42","first-page":"7542384","article-title":"Basic studies on the oxidative stress markers in two types of horse breed: Semi-isolated population of huculs is different from commercially used Arabian horses","volume":"2020","author":"Romuk","year":"2020","journal-title":"BioMed Res. Int."},{"key":"ref_43","first-page":"743","article-title":"Brown bowel syndrome: A rare malnutrition-related complication of bariatric surgery","volume":"36","author":"Soares","year":"2019","journal-title":"Nutr. Hosp."},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Jungert, A., and Neuh\u00e4user-Berthold, M. (2020). Interrelation between plasma concentrations of vitamins C and E along the trajectory of ageing in consideration of lifestyle and body composition: A longitudinal study over two decades. Nutrients, 12.","DOI":"10.3390\/nu12102944"}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/14\/19\/4097\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:45:25Z","timestamp":1760143525000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/14\/19\/4097"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,2]]},"references-count":44,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2022,10]]}},"alternative-id":["nu14194097"],"URL":"https:\/\/doi.org\/10.3390\/nu14194097","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,2]]}}}