{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T09:53:36Z","timestamp":1787910816494,"version":"build-2784847793"},"reference-count":31,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2022,11,26]],"date-time":"2022-11-26T00:00:00Z","timestamp":1669420800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Purpose: The purpose of this study was to evaluate the effect of a single intake of citrulline at 3 g and 6 g doses in adult elite soccer players performing sport-specific exercise. Materials and Methods: This randomized double-blind placebo-controlled study analyzed 18 soccer players from the top divisions of three European countries. Participants were randomized into three groups of six each and performed a field-based soccer-specific test for 18 min. Comparative analysis of heart rate, fatigue and post-exercise recovery was conducted. Results: There were no statistically significant differences in most of the analyzed parameters, nor at any of the time points for lactate concentration. Players\u2019 RPE exercise test score did not reveal any differences. Conclusions: Neither a single intake of 3 g nor of 6 g of citrulline malate affected physical performance, subjective feelings of fatigue or post-exercise recovery in adult elite soccer players who performed a soccer-specific test.<\/jats:p>","DOI":"10.3390\/nu14235036","type":"journal-article","created":{"date-parts":[[2022,11,28]],"date-time":"2022-11-28T07:01:30Z","timestamp":1669618890000},"page":"5036","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["The Effect of a Single Dose of Citrulline on the Physical Performance of Soccer-Specific Exercise in Adult Elite Soccer Players (A Pilot Randomized Double-Blind Trial)"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3828-0506","authenticated-orcid":false,"given":"Eduard","family":"Bezuglov","sequence":"first","affiliation":[{"name":"Department of Sports Medicine and Medical Rehabilitation, Sechenov First Moscow State Medical University of the Ministry of Health of the Russia, 119991 Moscow, Russia"},{"name":"High Performance Sports Laboratory, Moscow Witte University, 115432 Moscow, Russia"},{"name":"The Academy of the Russian Football Union, 115172 Moscow, Russia"},{"name":"PFC CSKA, 125167 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2007-4827","authenticated-orcid":false,"given":"Ryland","family":"Morgans","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine and Medical Rehabilitation, Sechenov First Moscow State Medical University of the Ministry of Health of the Russia, 119991 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7189-0766","authenticated-orcid":false,"given":"Artemii","family":"Lazarev","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Mount Sinai Hospital, Chicago, IL 60608, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgeny","family":"Kalinin","sequence":"additional","affiliation":[{"name":"Sports Adaptology Lab, Moscow Institute of Physics and Technology (National Research University), 141701 Dolgoprudniy, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikhail","family":"Butovsky","sequence":"additional","affiliation":[{"name":"Football Club \u201cRubin\u201d, 420036 Kazan, Russia"},{"name":"Department Neurology and Rehabilitation, Kazan State Medical University, 420012 Kazan, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgeny","family":"Savin","sequence":"additional","affiliation":[{"name":"Higher School of Economics, 101000 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduard","family":"Tzgoev","sequence":"additional","affiliation":[{"name":"The Academy of the Russian Football Union, 115172 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1512-8141","authenticated-orcid":false,"given":"Bekzhan","family":"Pirmakhanov","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Biostatistics and Evidence-Based Medicine, Faculty of Medicine and Health Care, Al-Farabi Kazakh National University, Almaty 050040, Kazakhstan"},{"name":"Football Club Kairat, Almaty 050054, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton","family":"Emanov","sequence":"additional","affiliation":[{"name":"\u201cSmart Recovery\u201d Sports Medicine Clinic LLC, 121552 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrey","family":"Zholinsky","sequence":"additional","affiliation":[{"name":"Federal Research and Clinical Center of Sports Medicine and Rehabilitation, Federal Medical Biological Agency, 121059 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oleg","family":"Talibov","sequence":"additional","affiliation":[{"name":"High Performance Sports Laboratory, Moscow Witte University, 115432 Moscow, Russia"},{"name":"Department of Internal Medicine, Clinical Pharmacology and Emergency Medicine, Moscow State University of Medicine and Dentistry, 127473 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"4395","DOI":"10.1021\/acs.jafc.7b00586","article-title":"Consumption of Watermelon Juice Enriched in l-Citrulline and Pomegranate Ellagitannins Enhanced Metabolism during Physical Exercise","volume":"65","author":"Alacid","year":"2017","journal-title":"J. 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