{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T20:06:25Z","timestamp":1790798785264,"version":"4.1.0"},"reference-count":24,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T00:00:00Z","timestamp":1671753600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>The pre-pregnancy BMI and the gestational weight gain are two important determinants of pregnancy outcomes. The aim of this study was to determine obstetric outcomes associated with insufficient gestational weight gain in women with a pre-pregnancy BMI &lt; 18.5 kg\/m2. This study was based on observational routinely collected data from University Hospital Maternity. The participants were allocated to the group sufficient or insufficient gestational weight gain: \u226512.5 kg and &lt;12.5 kg respectively. Primary outcomes were the adjusted birth weight in percentiles (%) and the proportion of SGA newborns. Secondary outcomes were obstetric and perinatal outcomes. A total of 132 participants with a median age of 28 \u00b1 8 years were included. The adjusted birth weight in percentiles was significantly lower in the insufficient gestational weight gain group (27.3 \u00b1 45.0 vs. 46.3 \u00b1 46.2%; p &lt; 0.001). Moreover, the insufficient gestational weight gain is associated with a higher risk of SGA (27.0% vs. 11.6%; p = 0.03). Our study also showed increased risks of premature rupture of membranes, anaemia, and intrauterine growth restriction in women with an insufficient weight gain. Future studies should explore the risk factors associated with insufficient weight gain, in order to develop specific care for underweight pregnant women.<\/jats:p>","DOI":"10.3390\/nu15010057","type":"journal-article","created":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T03:26:25Z","timestamp":1671765985000},"page":"57","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["In Underweight Women, Insufficient Gestational Weight Gain Is Associated with Adverse Obstetric Outcomes"],"prefix":"10.3390","volume":"15","author":[{"given":"Aliz\u00e9e","family":"Montvignier Monnet","sequence":"first","affiliation":[{"name":"Midwifery Department, Faculty of Medicine, University Grenoble Alpes, CHU Grenoble Alpes, 38000 Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Savoy","sequence":"additional","affiliation":[{"name":"Midwifery Department, Faculty of Medicine, University Grenoble Alpes, CHU Grenoble Alpes, 38000 Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lise","family":"Pr\u00e9aubert","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Gyn\u00e9cologie-Obst\u00e9trique & M\u00e9decine de la Reproduction, Centre Hospitalier Universitaire Grenoble Alpes (CHUGA), La Tronche, France, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale U1292, Biologie et Biotechnologie pour la Sant\u00e9, 38000 Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascale","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Gyn\u00e9cologie-Obst\u00e9trique & M\u00e9decine de la Reproduction, Centre Hospitalier Universitaire Grenoble Alpes (CHUGA), La Tronche, France, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale U1292, Biologie et Biotechnologie pour la Sant\u00e9, 38000 Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6729-2704","authenticated-orcid":false,"given":"C\u00e9cile","family":"B\u00e9try","sequence":"additional","affiliation":[{"name":"Univ. Grenoble Alpes, CNRS, UMR 5525, VetAgro Sup, Grenoble INP, DepartCHU Grenoble Alpes, TIMC, 38000 Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,23]]},"reference":[{"key":"ref_1","first-page":"339.e1-14","article-title":"A Systematic Review of Outcomes of Maternal Weight Gain According to the Institute of Medicine Recommendations: Birthweight, Fetal Growth, and Postpartum Weight Retention","volume":"201","author":"Viswanathan","year":"2009","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_2","unstructured":"Rasmussen, K.M., Yaktine, A.L., and Institute of Medicine (US) and National Research Council (US) Committee to Reexamine IOM Pregnancy Weight Summary (2009). 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