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The study included 952 centenarians (81.4% female). During a median follow-up of 32 months, 752 (78.9%) centenarians died. The estimated 1-year, 3-year, and 5-year survival rates were 80.0%, 45.7%, and 23.6%, respectively. The association of mortality with 25(OH)D was linear, whereas the associations with PTH and \u03b2-CTX were J-shaped, with a lower risk below the median levels. Compared with 25(OH)D of \u226530 ng\/mL, 25(OH)D &lt; 30 ng\/mL was associated with increased mortality (HR 1.52, 95% CI 1.24\u20131.86, p &lt; 0.001). Compared with PTH of \u226465 pg\/mL, PTH &gt; 65 pg\/mL was associated with increased mortality (HR 1.30, 95% CI 1.08\u20131.56, p = 0.005). Compared with \u03b2-CTX of &lt;0.55 ng\/mL, \u03b2-CTX \u2265 0.55 ng\/mL was associated with increased mortality (HR 1.30, 95% CI 1.10\u20131.54, p = 0.002). A higher \u03b2-CTX level (even in the clinical reference range of 0.55\u20131.01 ng\/mL) was associated with increased mortality (HR 1.23, 95% CI 1.04\u20131.47, p = 0.018). Centenarians with 25(OH)D &lt; 30 ng\/mL, PTH &gt; 65 pg\/mL, and \u03b2-CTX \u2265 0.55 ng\/mL had a 2.77-fold (95% CI 1.99\u20133.85, p &lt; 0.001) increased risk of mortality when compared with those with 25(OH)D of &gt;30 ng\/mL, PTH &lt; 65 pg\/mL, and \u03b2-CTX &lt; 0.55 ng\/mL. Lower serum 25(OH)D and higher PTH and \u03b2-CTX were independently correlated with increased all-cause mortality in Chinese community-dwelling centenarians.<\/jats:p>","DOI":"10.3390\/nu15010094","type":"journal-article","created":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T07:31:56Z","timestamp":1672126316000},"page":"94","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Associations of Serum 25(OH)D, PTH, and \u03b2-CTX Levels with All-Cause Mortality in Chinese Community-Dwelling Centenarians"],"prefix":"10.3390","volume":"15","author":[{"given":"Bin","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Academician Team Innovation Center, Sanya 572013, China"},{"name":"Senior Department of Nephrology, The First Medical Center of Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Beijing 100853, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaowei","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Academician Team Innovation Center, Sanya 572013, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shihui","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya 572013, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ding","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Academician Team Innovation Center, Sanya 572013, 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China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyu","family":"Miao","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Academician Team Innovation Center, Sanya 572013, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Academician Team Innovation Center, Sanya 572013, 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