{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:49:19Z","timestamp":1792036159059,"version":"4.4.0"},"reference-count":51,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T00:00:00Z","timestamp":1674518400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University of Sherbrooke"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Maximal oxygen consumption (V\u02d9O2max) is a major determinant of 5-km running time-trial (TT) performance. Glycerol-induced hyperhydration (GIH) could improve V\u02d9O2max in recreationally active persons through an optimal increase in plasma volume. Moreover, ingestion of a large bolus of cold fluid before exercise could decrease thermal stress during exercise, potentially contributing to improved performance. We determined the effect of GIH on 5-km running TT performance in 10 recreationally active individuals (age: 24 \u00b1 4 years; V\u02d9O2max: 48 \u00b1 3 mL\/kg\/min). Using a randomized and counterbalanced protocol, participants underwent two, 120-min hydration protocols where they ingested a 1) 30 mL\/kg fat-free mass (FFM) of cold water (~4 \u00b0C) with an artificial sweetener + 1.4 g glycerol\/kg FFM over the first 60 min (GIH) or 2) 7.5 mL\/kg FFM of cold water with an artificial sweetener over the first 20 min (EUH). Following GIH and EUH, participants underwent a 5-km running TT at 30 \u00b0C and 50% relative humidity. After 120 min, GIH was associated with significantly greater fluid retention (846 \u00b1 415 mL) and plasma volume changes (10.1 \u00b1 8.4%) than EUH, but gastrointestinal (GI) temperature did not differ. During exercise, 5-km running TT performance (GIH: 22.95 \u00b1 2.62; EUH: 22.52 \u00b1 2.74 min), as well as heart rate, GI temperature and perceived exertion did not significantly differ between conditions. This study demonstrates that the additional body water and plasma volume gains provided by GIH do not improve 5-km running TT performance in the heat in recreationally active individuals.<\/jats:p>","DOI":"10.3390\/nu15030599","type":"journal-article","created":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T04:22:16Z","timestamp":1674620536000},"page":"599","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Effect of Glycerol-Induced Hyperhydration on a 5-kilometer Running Time-Trial Performance in the Heat in Recreationally Active Individuals"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1315-846X","authenticated-orcid":false,"given":"Antoine","family":"Jolicoeur Desroches","sequence":"first","affiliation":[{"name":"Faculty of Physical Activity Sciences, University of Sherbrooke, Sherbrooke, QC J1K 2R1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Naulleau","sequence":"additional","affiliation":[{"name":"Faculty of Physical Activity Sciences, University of Sherbrooke, Sherbrooke, QC J1K 2R1, Canada"},{"name":"Institut National du Sport du Qu\u00e9bec, Montr\u00e9al, QC H1V 3N7, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7620-1939","authenticated-orcid":false,"given":"Thomas A.","family":"Deshayes","sequence":"additional","affiliation":[{"name":"Faculty of Physical Activity Sciences, University of Sherbrooke, Sherbrooke, QC J1K 2R1, Canada"},{"name":"Research Centre on Aging, University of Sherbrooke, Sherbrooke, QC J1H 4C4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1649-2735","authenticated-orcid":false,"given":"Hugo","family":"Parent-Roberge","sequence":"additional","affiliation":[{"name":"Faculty of Physical Activity Sciences, University of Sherbrooke, Sherbrooke, QC J1K 2R1, Canada"},{"name":"Research Centre on Aging, University of Sherbrooke, Sherbrooke, QC J1H 4C4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timoth\u00e9e","family":"Pancrate","sequence":"additional","affiliation":[{"name":"Faculty of Physical Activity Sciences, University of Sherbrooke, Sherbrooke, QC J1K 2R1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5117-9977","authenticated-orcid":false,"given":"Eric D. B.","family":"Goulet","sequence":"additional","affiliation":[{"name":"Faculty of Physical Activity Sciences, University of Sherbrooke, Sherbrooke, QC J1K 2R1, Canada"},{"name":"Research Centre on Aging, University of Sherbrooke, Sherbrooke, QC J1H 4C4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1136\/bjsm.21.2.9","article-title":"Determinants of five kilometre running performance in active men and women","volume":"21","author":"Ramsbottom","year":"1987","journal-title":"Br. J. Sports Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1080\/02640419208729914","article-title":"Physiological and metabolic responses of men and women to a 5-km treadmill time trial","volume":"10","author":"Ramsbottom","year":"1992","journal-title":"J. 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