{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T14:36:37Z","timestamp":1790778997289,"version":"4.1.0"},"reference-count":142,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,2,6]],"date-time":"2023-02-06T00:00:00Z","timestamp":1675641600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000025","name":"Connecticut Council on Problem Gambling","doi-asserted-by":"publisher","award":["RF1 MH128614"],"award-info":[{"award-number":["RF1 MH128614"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"Connecticut Council on Problem Gambling","doi-asserted-by":"publisher","award":["NIDDK R01"],"award-info":[{"award-number":["NIDDK R01"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"Connecticut Council on Problem Gambling","doi-asserted-by":"publisher","award":["DK121551"],"award-info":[{"award-number":["DK121551"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>The reward system is highly relevant to behavioral addictions such as gambling disorder (GD), internet gaming disorder (IGD), and food addiction\/binge eating disorder (FA\/BED). Among other brain regions, the ventral striatum (VS) has been implicated in reward processing. The main objective of the present state-of-the-art review was to explore in depth the specific role of the VS in GD, IGD and FA\/BED, understanding it as a possible biomarker of these conditions. Studies analyzing brain changes following interventions for these disorders, and especially those that had explored possible treatment-related changes in VS, are discussed. More evidence is needed on how existing treatments (both pharmacological and psychobehavioral) for behavioral addictions affect the activation of the VS and related circuitry.<\/jats:p>","DOI":"10.3390\/nu15040827","type":"journal-article","created":{"date-parts":[[2023,2,6]],"date-time":"2023-02-06T05:29:05Z","timestamp":1675661345000},"page":"827","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Potential Biological Markers and Treatment Implications for Binge Eating Disorder and Behavioral Addictions"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5345-0484","authenticated-orcid":false,"given":"Gemma","family":"Mestre-Bach","sequence":"first","affiliation":[{"name":"Facultad de Ciencias de la Salud, Universidad Internacional de La Rioja, 26006 Logro\u00f1o, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6323-1354","authenticated-orcid":false,"given":"Marc N.","family":"Potenza","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, School of Medicine, Yale University, New Haven, CT 06510, USA"},{"name":"Connecticut Mental Health Center, New Haven, CT 06519, USA"},{"name":"Connecticut Council on Problem Gambling, Wethersfield, CT 06109, USA"},{"name":"Wu Tsai Institute, Yale University, New Haven, CT 06510, USA"},{"name":"Yale Child Study Center, School of Medicine, Yale University, New Haven, CT 06510, USA"},{"name":"Department of Neuroscience, School of Medicine, Yale University, New Haven, CT 06510, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1093\/scan\/nsaa104","article-title":"Sex differences in the human reward system: Convergent behavioral, autonomic and neural evidence","volume":"15","author":"Warthen","year":"2020","journal-title":"Soc. 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