{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T13:38:16Z","timestamp":1780925896807,"version":"3.54.1"},"reference-count":52,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T00:00:00Z","timestamp":1675814400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Medical University of Lodz Poland","award":["503\/1-000-01\/503-11-001-19-00"],"award-info":[{"award-number":["503\/1-000-01\/503-11-001-19-00"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: Adipose tissue is not only a storage place for fat, but also an endocrine organ, secreting bioactive molecules which influence body metabolism. Such molecules are known as adipocytokines. In the past years the coincidence between adipocytokines and fetal growth restriction disorders was found. The aim of the study was to estimate serum levels of adiponectin, leptin and resistin in children born small for gestational age, compared to children born at an appropriate size for gestational age. Methods: The study consisted of 35 children aged seven to nine years, born SGA (small for gestational age) on term and 25 healthy children (14 girls, 11 boys), born with proper birthweight (AGA\u2014appropriate for gestational age)\u2013control group. Results: Adiponectin and leptin levels were significantly higher in the SGA group compared to the AGA group (p = 0.023, p = 0.018 respectively). The resistin values were comparable in both groups of patients. There was a positive correlation between serum leptin concentration and current body weight in SGA group (r = 0.28; p = 0.108). In turn, adiponectin levels in this group of patients negatively correlated with actual body weight (r = \u22120.51; p = 0.002). The negative correlation between body mass index and plasma adiponectin levels was found only in children born SGA. SGA children had significantly higher values of diastolic blood pressure. There was negative correlation between serum adiponectin level and systolic blood pressure in SGA children. In the SGA group the phenomenon of catch-up growth was observed in 32 children. Conclusions: Children born SGA have abnormal adipose tissue biomarkers profiles.<\/jats:p>","DOI":"10.3390\/nu15040868","type":"journal-article","created":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T02:55:54Z","timestamp":1675911354000},"page":"868","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Serum Adipocytokines Profile in Children Born Small and Appropriate for Gestational Age\u2014A Comparative Study"],"prefix":"10.3390","volume":"15","author":[{"given":"Justyna","family":"Zamojska","sequence":"first","affiliation":[{"name":"Department of Pediatric Cardiology and Rheumatology, Medical University of Lodz, 90-008 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarzyna","family":"Niewiadomska-Jarosik","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology and Rheumatology, Medical University of Lodz, 90-008 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6124-1236","authenticated-orcid":false,"given":"Agnieszka","family":"Wosiak","sequence":"additional","affiliation":[{"name":"Institute of Information Technology, Lodz University of Technology, 90-008 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2780-2164","authenticated-orcid":false,"given":"Marta","family":"Gruca","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology and Rheumatology, Medical University of Lodz, 90-008 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"El\u017cbieta","family":"Smolewska","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology and Rheumatology, Medical University of Lodz, 90-008 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,8]]},"reference":[{"key":"ref_1","unstructured":"(2023, January 14). 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