{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:31:24Z","timestamp":1790645484045,"version":"4.1.0"},"reference-count":41,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T00:00:00Z","timestamp":1679356800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Soci\u00e9t\u00e9 Francophone d\u2019OncoGeriatrie (SoFOG)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Older cancer patients have an elevated risk of sarcopenia. The aim was to estimate the prevalence of four criteria for sarcopenia case finding, assessment, diagnosis, and severity determination: abnormal strength, assistance with walking, rising from a chair, climbing stairs, and falls (SARC-F), low hand-grip strength (HGS), low arm circumference (AC, a muscle mass proxy), and low physical performance (PP). Sarcopenia (low HGS and AC) and severe sarcopenia (low HGS, AC, and PP) and their predictive values for 6-month mortality were estimated in the whole population and by metastatic status. We analyzed data from the NutriAgeCancer French nationwide study of cancer patients aged \u226570 referred for geriatric assessment before anti-cancer treatment. We performed Cox proportional hazards analysis for each criterion separately and all criteria combined. Overall, 781 patients from 41 geriatric oncology clinics were included (mean age: 83.1; females: 53%; main cancer types: digestive (29%) and breast (17%); metastases: 42%). The prevalence of abnormal SARC-F, low HGS, a low AC, low PP, sarcopenia, and severe sarcopenia were, respectively, 35.5%, 44.6%, 44.7%, 35.2%, 24.5%, and 11.7%. An abnormal SARC-F and\/or low HGS, sarcopenia, and severe sarcopenia were associated with 6-month mortality in patients with metastases (adjusted hazard ratios [95% confidence interval]: 2.72 [1.34\u20135.49], 3.16 [1.48\u20136.75] and 6.41 [2.5\u201316.5], respectively). Sarcopenia was strongly predictive of 6-month mortality in patients with metastatic cancer.<\/jats:p>","DOI":"10.3390\/nu15061508","type":"journal-article","created":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T04:48:01Z","timestamp":1679374081000},"page":"1508","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Prevalence of Four Sarcopenia Criteria in Older Patients with Cancer, and Their Predictive Value for 6-Month Mortality: The NutriAgeCancer National Prospective Cohort Study"],"prefix":"10.3390","volume":"15","author":[{"given":"Claudia","family":"Martinez-Tapia","sequence":"first","affiliation":[{"name":"Univ Paris Est Cr\u00e9teil, INSERM, IMRB, F-94010 Cr\u00e9teil, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Rougette","sequence":"additional","affiliation":[{"name":"Assistance Publique-H\u00f4pitaux de Paris (AP-HP), Paris Cancer Institute CARPEM, Georges Pompidou European Hospital, Department of Geriatric Medicine, Oncogeriatric Coordination Unit (UCOG), F-75015 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3266-0778","authenticated-orcid":false,"given":"Virginie","family":"Fossey-Diaz","sequence":"additional","affiliation":[{"name":"AP-HP, H\u00f4pital Bretonneau, Service de G\u00e9riatrie, UCOG Paris Nord, F-75018 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tristan","family":"Cudennec","sequence":"additional","affiliation":[{"name":"AP-HP, H\u00f4pital Ambroise-Par\u00e9, Department of Geriatrics, UCOG Paris Ouest, F-92100 Boulogne-Billancourt, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cherifa","family":"Taleb","sequence":"additional","affiliation":[{"name":"AP-HP, H\u00f4pital Ren\u00e9-Muret, Service de G\u00e9riatrie, HUPSSD, UCOG Paris Seine Saint Denis, F-93270 Sevran, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Balardy","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire de Toulouse, Geriatric Department, Internal Medicine and Oncogeriatry Unit, UCOG Midi-Pyr\u00e9n\u00e9es, F-31000 Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Mertens","sequence":"additional","affiliation":[{"name":"CHU Bordeaux, Clinical Gerontology Department, Aquitaine Interregional UCOG, F-33000 Bordeaux, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Mitha","sequence":"additional","affiliation":[{"name":"CHU de Grenoble Alpes, Geriatric Medicine Department, UCOG Arc Alpin, F-38700 Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Bringuier","sequence":"additional","affiliation":[{"name":"Institut Curie, PSL Research University, Department of Medical Oncology and Department of Supportive Care, UCOG Paris Ouest, F-92210 Saint-Cloud, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Maley","sequence":"additional","affiliation":[{"name":"Groupe Hospitalier Diaconesses-Croix-Saint-Simon, Geriatric Medicine Department, UCOG Paris Est, F-75020 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandrine","family":"Estivin","sequence":"additional","affiliation":[{"name":"Brest University Hospital, Internal Medicine and Geriatrics, UCOG de Bretagne, F-29200 Brest, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Quipourt","sequence":"additional","affiliation":[{"name":"Dijon University Hospital, Department of Geriatrics and Internal Medicine, Bourgogne Interregional UCOG, F-21000 Dijon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Canoui-Poitrine","sequence":"additional","affiliation":[{"name":"Univ Paris Est Cr\u00e9teil, INSERM, IMRB, F-94010 Cr\u00e9teil, France"},{"name":"AP-HP, Henri-Mondor Hospital, Public Health Department, F-94010 Creteil, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0604-7614","authenticated-orcid":false,"given":"Capucine","family":"Baldini","sequence":"additional","affiliation":[{"name":"Drug Development Department DITEP, Gustave Roussy, F-94800 Villejuif, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanne","family":"Poisson","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Cit\u00e9, Inserm, Centre de Recherche sur L\u2019inflammation, UMR 1149, F-75018 Paris, France"},{"name":"AP-HP, Oncogeriatric Coordination Unit (UCOG), Department of Geriatric Medicine, Georges Pompidou European Hospital, Paris Cancer Institute CARPEM, F-75015 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5579-9927","authenticated-orcid":false,"given":"Elena","family":"Paillaud","sequence":"additional","affiliation":[{"name":"Univ Paris Est Cr\u00e9teil, INSERM, IMRB, F-94010 Cr\u00e9teil, France"},{"name":"Assistance Publique-H\u00f4pitaux de Paris (AP-HP), Paris Cancer Institute CARPEM, Georges Pompidou European Hospital, Department of Geriatric Medicine, Oncogeriatric Coordination Unit (UCOG), F-75015 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1093\/ageing\/afz046","article-title":"Sarcopenia: Revised European consensus on definition and diagnosis","volume":"48","author":"Bahat","year":"2019","journal-title":"Age 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