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Endogenous and exogenous factors such as abnormal GI motility, low-grade inflammation, increased epithelial permeability and visceral hypersensitivity, but diet and psychosocial aspects are also recognized as important actors. Furthermore, the interaction between diet and gut microbiota has gained interest as a potential contributor to the pathophysiology of IBS. To date, there is no specific diet for IBS with constipation (IBS-C); however, many studies show that fiber intake, especially soluble fiber such as inulin, could have a positive effect on symptoms. This review aims to evaluate the effects of some nutritional components such as fibers but also functional foods, prebiotics, probiotics and symbiotics on symptoms and microbiota in IBS-C subjects.<\/jats:p>","DOI":"10.3390\/nu15071647","type":"journal-article","created":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T01:33:00Z","timestamp":1680053580000},"page":"1647","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":70,"title":["Constipation-Predominant Irritable Bowel Syndrome (IBS-C): Effects of Different Nutritional Patterns on Intestinal Dysbiosis and Symptoms"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5465-5657","authenticated-orcid":false,"given":"Claudia","family":"Di Rosa","sequence":"first","affiliation":[{"name":"Research Unit of Food Science and Human Nutrition, Department of Science and Technology for Humans and the Environment, Universit\u00e0 Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21-00128 Roma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8630-7836","authenticated-orcid":false,"given":"Annamaria","family":"Altomare","sequence":"additional","affiliation":[{"name":"Research Unit of Gastroenterology, Universit\u00e0 Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21-00128 Roma, Italy"},{"name":"Operative Research Unit of Gastroenterology, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200-00128 Roma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1093-1628","authenticated-orcid":false,"given":"Vittoria","family":"Terrigno","sequence":"additional","affiliation":[{"name":"Research Unit of Food Science and Human Nutrition, Department of Science and Technology for Humans and the Environment, Universit\u00e0 Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21-00128 Roma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florencia","family":"Carbone","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospitals Leuven, 3000 Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Tack","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospitals Leuven, 3000 Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Cicala","sequence":"additional","affiliation":[{"name":"Research Unit of Gastroenterology, Universit\u00e0 Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21-00128 Roma, Italy"},{"name":"Operative Research Unit of Gastroenterology, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200-00128 Roma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Guarino","sequence":"additional","affiliation":[{"name":"Research Unit of Gastroenterology, Universit\u00e0 Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21-00128 Roma, Italy"},{"name":"Operative Research Unit of Gastroenterology, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200-00128 Roma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1053\/j.gastro.2016.02.032","article-title":"Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV","volume":"150","author":"Drossman","year":"2016","journal-title":"Gastroenterology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1053\/j.gastro.2016.02.031","article-title":"Bowel disorders","volume":"150","author":"Lacy","year":"2016","journal-title":"Gastroenterology"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"360","DOI":"10.51821\/85.2.10100","article-title":"Belgian consensus on irritable bowel syndrome","volume":"85","author":"Kindt","year":"2022","journal-title":"Acta Gastroenterol. 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