{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T14:25:30Z","timestamp":1789136730712,"version":"build-2803163510"},"reference-count":60,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T00:00:00Z","timestamp":1680134400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Algerian Government Bourse excellence alg\u00e9rienne","award":["AOI 8426"],"award-info":[{"award-number":["AOI 8426"]}]},{"name":"Stichting FSHD","award":["AOI 8426"],"award-info":[{"award-number":["AOI 8426"]}]},{"name":"Amis FSH Europe","award":["AOI 8426"],"award-info":[{"award-number":["AOI 8426"]}]},{"name":"Montpellier University Hospital","award":["AOI 8426"],"award-info":[{"award-number":["AOI 8426"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>In patients with facioscapulohumeral muscular dystrophy (FSHD), a rare genetic neuromuscular disease, reduced physical performance is associated with lower blood levels of vitamin C, zinc, selenium, and increased oxidative stress markers. Supplementation of vitamin C, vitamin E, zinc, and selenium improves the quadriceps\u2019 physical performance. Here, we compared the nutritional status of 74 women and 85 men with FSHD. Calorie intake was lower in women with FSHD than in men. Moreover, we assessed vitamin C, vitamin E, zinc, copper, and selenium intakes in diet and their concentrations in the plasma. Vitamin E, copper, and zinc intake were lower in women with FSHD than in men, whereas plasma vitamin C, copper levels, and copper\/zinc ratio were higher in women with FSHD than in men. The dietary intake and plasma concentrations of the studied vitamins and minerals were not correlated in both sexes. A well-balanced and varied diet might not be enough in patients with FSHD to correct the observed vitamin\/mineral deficiencies. A low energy intake is a risk factor for suboptimal intake of proteins, vitamins, and minerals that are important for protein synthesis and other metabolic pathways and that might contribute to progressive muscle mass loss. Antioxidant supplementation and higher protein intake seem necessary to confer protection against oxidative stress and skeletal muscle mass loss.<\/jats:p>","DOI":"10.3390\/nu15071673","type":"journal-article","created":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T01:05:26Z","timestamp":1680138326000},"page":"1673","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Nutritional Status of Patients with Facioscapulohumeral Muscular Dystrophy"],"prefix":"10.3390","volume":"15","author":[{"given":"Sedda","family":"Amzali","sequence":"first","affiliation":[{"name":"PhyMedExp, Universit\u00e9 de Montpellier, INSERM, CNRS, CHU de Montpellier, 34295 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3877-344X","authenticated-orcid":false,"given":"Vinicius Dias","family":"Wilson","sequence":"additional","affiliation":[{"name":"Departamento de Educa\u00e7\u00e3o F\u00edsica, Centro Universit\u00e1rio Est\u00e1cio de Belo Horizonte, Belo Horizonte 30411-052, Minas Gerais, Brazil"},{"name":"Pr\u00f3-Reitoria de Assuntos Comunit\u00e1rios e Estudantis, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina 39100-000, Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7288-3573","authenticated-orcid":false,"given":"S\u00e9bastien","family":"Bommart","sequence":"additional","affiliation":[{"name":"PhyMedExp, Universit\u00e9 de Montpellier, INSERM, CNRS, CHU de Montpellier, 34295 Montpellier, France"},{"name":"Service de Radiologie, H\u00f4pital Arnaud-de-Villeneuve, CHU de Montpellier, 34295 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4204-7299","authenticated-orcid":false,"given":"Marie-Christine","family":"Picot","sequence":"additional","affiliation":[{"name":"Clinical Research and Epidemiology Unit (Department of Medicale Information), Centre d\u2019Investigation Clinique 1411 INSERM, CHU Montpellier, Univ Montpellier, CEDEX 5, 34295 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1717-1266","authenticated-orcid":false,"given":"Simon","family":"Galas","sequence":"additional","affiliation":[{"name":"Institut des Biomolecules Max Mousseron (IBMM), Centre National de Recherche Scientifique (CNRS), University of Montpellier, ENSCM, 34000 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7583-1069","authenticated-orcid":false,"given":"Jacques","family":"Mercier","sequence":"additional","affiliation":[{"name":"PhyMedExp, Universit\u00e9 de Montpellier, INSERM, CNRS, CHU de Montpellier, 34295 Montpellier, France"},{"name":"Department of Clinical Physiology, CHU of Montpellier, 34295 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Poucheret","sequence":"additional","affiliation":[{"name":"Qualisud, Universit\u00e9 de Montpellier, CIRAD, Institut Agro, IRD, Avignon Universit\u00e9, Universit\u00e9 de La R\u00e9union, 34000 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8563-7278","authenticated-orcid":false,"given":"Jean-Paul","family":"Cristol","sequence":"additional","affiliation":[{"name":"PhyMedExp, Universit\u00e9 de Montpellier, INSERM, CNRS, CHU de Montpellier, 34295 Montpellier, France"},{"name":"Department of Biochemistry, University Hospital of Montpellier, 34295 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5228-2255","authenticated-orcid":false,"given":"Sandrine","family":"Arbogast","sequence":"additional","affiliation":[{"name":"PhyMedExp, Universit\u00e9 de Montpellier, INSERM, CNRS, CHU de Montpellier, 34295 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4356-9187","authenticated-orcid":false,"given":"Dalila","family":"Laoudj-Chenivesse","sequence":"additional","affiliation":[{"name":"PhyMedExp, Universit\u00e9 de Montpellier, INSERM, CNRS, CHU de Montpellier, 34295 Montpellier, France"},{"name":"Department of Clinical Physiology, CHU of Montpellier, 34295 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1111\/j.1399-0004.2009.01158.x","article-title":"Facioscapulohumeral Muscular Dystrophy: Epidemiological and Molecular Study in a North-East Italian Population Sample","volume":"75","author":"Mostacciuolo","year":"2009","journal-title":"Clin. 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