{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T22:41:10Z","timestamp":1788475270266,"version":"build-2803163510"},"reference-count":46,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T00:00:00Z","timestamp":1680566400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"FEDER\/Junta de Andaluc\u00eda-Consejer\u00eda de Transformaci\u00f3n Econ\u00f3mica, Industria, Conocimiento y Universidades","award":["B-AGR-658"],"award-info":[{"award-number":["B-AGR-658"]}]},{"name":"\u201cInvestigation grant program by the Association of Celiacs and Sensitive to Gluten of the Community of Madrid\u201d","award":["B-AGR-658"],"award-info":[{"award-number":["B-AGR-658"]}]},{"name":"BIOMEDAL S.L.","award":["B-AGR-658"],"award-info":[{"award-number":["B-AGR-658"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>A gluten-free diet (GFD) is the only treatment available for celiac disease (CD); hence, it is important to ensure correct adherence to the diet and adequate monitoring of the diet. The present study aims to assess the importance of an early follow-up of celiac patients after diagnosis of the disease, identify the role of stool gluten immunogenic peptides (GIPs) in the assessment of GFD adherence, and analyze possible nutritional imbalances or deficiencies in the GFD. This is a cross-sectional study carried out in pediatric patients with newly diagnosed CD in a tertiary hospital in Spain. Of the 61 patients included, 14% had positive stool GIPS at 4 months after CD diagnosis, Among them, 88% had negative stool GIPS at 9 months after diagnosis, following dietary advice. We found nutritional deficiencies in the GFD, such as vitamin D (with only 27% of patients with adequate intakes), folate, calcium, magnesium, and fiber. Similarly, we found imbalances: excess protein and fat intakes and a high percentage of total daily energy intake came from ultra-processed foods (UPF). These findings emphasize the importance of early follow-up of children after diagnosis of CD. It is also crucial to identify patients with poor GFD compliance based on stool GIPS and analyze GFD nutritional imbalances and deficits. Our findings may contribute to the development of specific strategies for the early follow-up of patients with CD, including appropriate nutritional counselling.<\/jats:p>","DOI":"10.3390\/nu15071761","type":"journal-article","created":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T04:09:50Z","timestamp":1680581390000},"page":"1761","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The Importance of an Early Evaluation after Establishing a Gluten-Free Diet in Children with Celiac Disease"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0113-9904","authenticated-orcid":false,"given":"Rafael","family":"Mart\u00edn-Masot","sequence":"first","affiliation":[{"name":"Pediatric Gastroenterology and Nutrition Unit, Hospital Regional Universitario de Malaga, 29010 M\u00e1laga, Spain"},{"name":"Institute of Nutrition and Food Technology \u201cJos\u00e9 MataixVerd\u00fa\u201d (INYTA), Biomedical Research Centre (CIBM), University of Granada, 18071 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Jim\u00e9nez-Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Pediatric Gastroenterology and Nutrition Unit, Hospital Regional Universitario de Malaga, 29010 M\u00e1laga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4093-4900","authenticated-orcid":false,"given":"Marta","family":"Herrador-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Pediatric Gastroenterology and Nutrition Unit, Hospital Regional Universitario de Malaga, 29010 M\u00e1laga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8256-5053","authenticated-orcid":false,"given":"Marta","family":"Flor-Alemany","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Food Technology \u201cJos\u00e9 MataixVerd\u00fa\u201d (INYTA), Biomedical Research Centre (CIBM), University of Granada, 18071 Granada, Spain"},{"name":"Department of Physiology, Faculty of Pharmacy, University of Granada, 18071 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3004-252X","authenticated-orcid":false,"given":"V\u00edctor Manuel","family":"Navas-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Pediatric Gastroenterology and Nutrition Unit, Hospital Regional Universitario de Malaga, 29010 M\u00e1laga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9573-3244","authenticated-orcid":false,"given":"Teresa","family":"Nestares","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Food Technology \u201cJos\u00e9 MataixVerd\u00fa\u201d (INYTA), Biomedical Research Centre (CIBM), University of Granada, 18071 Granada, Spain"},{"name":"Department of Physiology, Faculty of Pharmacy, University of Granada, 18071 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1053\/gast.2000.8521","article-title":"Current Concepts of Celiac Disease Pathogenesis","volume":"119","author":"Schuppan","year":"2000","journal-title":"Gastroenterology"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Caio, G., Volta, U., Sapone, A., Leffler, D.A., de Giorgio, R., Catassi, C., and Fasano, A. 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