{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T01:02:10Z","timestamp":1768870930084,"version":"3.49.0"},"reference-count":95,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T00:00:00Z","timestamp":1681516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100020138","name":"Faculty of Biotechnology and Food Science, Wroclaw University of Environmental and Life Sciences","doi-asserted-by":"publisher","award":["B030\/0015\/16"],"award-info":[{"award-number":["B030\/0015\/16"]}],"id":[{"id":"10.13039\/501100020138","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020138","name":"Faculty of Biotechnology and Food Science, Wroclaw University of Environmental and Life Sciences","doi-asserted-by":"publisher","award":["P\/2016\/4"],"award-info":[{"award-number":["P\/2016\/4"]}],"id":[{"id":"10.13039\/501100020138","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Wroclaw Centre of Biotechnology, program: The Leading National Research Centre (KNOW) for years 2014\u20132018","award":["B030\/0015\/16"],"award-info":[{"award-number":["B030\/0015\/16"]}]},{"name":"Wroclaw Centre of Biotechnology, program: The Leading National Research Centre (KNOW) for years 2014\u20132018","award":["P\/2016\/4"],"award-info":[{"award-number":["P\/2016\/4"]}]},{"name":"Wroclaw University of Environmental and Life Sciences","award":["B030\/0015\/16"],"award-info":[{"award-number":["B030\/0015\/16"]}]},{"name":"Wroclaw University of Environmental and Life Sciences","award":["P\/2016\/4"],"award-info":[{"award-number":["P\/2016\/4"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>The nutritional status of pregnant women is considered to affect fetal development and the health condition of newborns, including their immune system. We investigated the relationship between the concentrations of magnesium (Mg), calcium (Ca), zinc (Zn), iron (Fe) and copper (Cu) in maternal serum (MS) and the concentrations of IgG antibodies and antineutrophil cytoplasmatic auto-antibodies against lactoferrin (Lf-ANCA) in umbilical cord serum (UCS). IgG was considered as a promoter of immunity, and Lf-ANCA as an inhibitor. The examined group consisted of 98 pregnant women and their healthy term newborn children. The concentrations of mineral elements were measured by FAAS\/FAES, while the concentrations of antibodies were determined by ELISA. Excessive MS Fe and insufficient MS Cu were related to insufficient UCS IgG and excessive UCS Lf-ANCA. The correlation analysis showed confirming results. Adequate UCS IgG and Lf-ANCA were related to MS Mg at the strictly lower limit of the reference values. The results obtained seem to suggest that an excess of Fe and a deficiency of Cu in pregnancy may adversely affect some immune parameters of newborns. Reference values for MS Mg are likely to require reconsideration. It would be advisable to monitor the nutritional status of pregnant women with minerals in order to support the immune capacity of newborns.<\/jats:p>","DOI":"10.3390\/nu15081908","type":"journal-article","created":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T01:34:15Z","timestamp":1681695255000},"page":"1908","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Some Immune Parameters of Term Newborns at Birth Are Associated with the Concentration of Iron, Copper and Magnesium in Maternal Serum"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6760-3274","authenticated-orcid":false,"given":"Karolina","family":"Rak","sequence":"first","affiliation":[{"name":"Department of Human Nutrition, Faculty of Biotechnology and Food Science, Wroclaw University of Environmental and Life Sciences, 51-630 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marzena","family":"Styczy\u0144ska","sequence":"additional","affiliation":[{"name":"Department of Human Nutrition, Faculty of Biotechnology and Food Science, Wroclaw University of Environmental and Life Sciences, 51-630 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michaela","family":"Godyla-Jab\u0142o\u0144ski","sequence":"additional","affiliation":[{"name":"Department of Human Nutrition, Faculty of Biotechnology and Food Science, Wroclaw University of Environmental and Life Sciences, 51-630 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2960-6981","authenticated-orcid":false,"given":"Monika","family":"Bronkowska","sequence":"additional","affiliation":[{"name":"Institute of Health Sciences, Collegium Salutis Humanae, University of Opole, 45-060 Opole, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1111\/all.14736","article-title":"Breastfeeding promotes early neonatal regulatory T-cell expansion and immune tolerance of non-inherited maternal antigens","volume":"76","author":"Wood","year":"2021","journal-title":"Allergy"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Maggini, S., Pierre, A., and Calder, P.C. 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