{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T21:34:24Z","timestamp":1768253664662,"version":"3.49.0"},"reference-count":46,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T00:00:00Z","timestamp":1684972800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>The aim of this study was to investigate associations between serum magnesium levels with insomnia and excessive daytime sleepiness (EDS) in older adults. A total of 938 older outpatients were included in the study. Hypomagnesemia was defined as serum magnesium concentration below &lt;1.6 mg\/dL. Patients were divided into two groups: hypomagnesemia and normomagnesia (1.6\u20132.6 mg\/dL). The Epworth Sleepiness Scale was implemented and scores of \u226511 points were categorized as EDS. The Insomnia Severity Index was implemented and scores of \u22658 indicated insomnia. The mean age was 81.1 \u00b1 7.6 years. While the presence of EDS, hypertension, diabetes mellitus, and coronary artery disease were more common in the hypomagnesemia group than the normomagnesia group, Parkinson\u2019s disease was less common (p &lt; 0.05). Hemoglobin and HDL cholesterol were lower, whereas HbA1c, triglyceride, and number of drugs used were higher in the hypomagnesemia group compared to the normomagnesia group (p &lt; 0.05). In both univariate analysis and multivariate analysis adjusted for gender, age and all confounders, there were significant associations between hypomagnesemia and EDS [odds ratio (OR):1.7; 95% confidence interval (CI): 1.6\u20132.6, and OR: 1.9; 95%CI: 1.2\u20133.3, respectively (p &lt; 0.05)]. There was no significant relationship between hypomagnesemia and insomnia (p &gt; 0.05). The present study identified an association between hypomagnesemia and EDS in older adults. Therefore, it may be prudent to consider hypomagnesemia when evaluating older adults with EDS and vice versa.<\/jats:p>","DOI":"10.3390\/nu15112467","type":"journal-article","created":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T02:00:19Z","timestamp":1685066419000},"page":"2467","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Hypomagnesemia Is Associated with Excessive Daytime Sleepiness, but Not Insomnia, in Older Adults"],"prefix":"10.3390","volume":"15","author":[{"given":"Muhammed","family":"Tunc","sequence":"first","affiliation":[{"name":"Division of Internal Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul 34093, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6042-1718","authenticated-orcid":false,"given":"Pinar","family":"Soysal","sequence":"additional","affiliation":[{"name":"Division of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul 34093, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozge","family":"Pasin","sequence":"additional","affiliation":[{"name":"Division of Biostatistics, Faculty of Medicine, Bezmialem Vakif University, Istanbul 34093, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5340-9833","authenticated-orcid":false,"given":"Lee","family":"Smith","sequence":"additional","affiliation":[{"name":"Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge CB1 1PT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4792-027X","authenticated-orcid":false,"given":"Masoud","family":"Rahmati","sequence":"additional","affiliation":[{"name":"Division of Physical Education and Sport Sciences, Faculty of Literature and Human Sciences, Lorestan University, Khoramabad 68151-44316, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0320-7253","authenticated-orcid":false,"given":"Veliye","family":"Yigitalp","sequence":"additional","affiliation":[{"name":"Division of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul 34093, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sevnaz","family":"Sahin","sequence":"additional","affiliation":[{"name":"Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Ege University, Izmir 35040, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6662-8832","authenticated-orcid":false,"given":"Moustapha","family":"Dram\u00e9","sequence":"additional","affiliation":[{"name":"Division of Clinical Research and Innovation, University Hospitals of Martinique, 97261 Fort-de-France, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,25]]},"reference":[{"key":"ref_1","first-page":"303","article-title":"Brain and CSF magnesium concentrations during magnesium deficit in animals and humans: Neurolog\u0131cal symptoms","volume":"5","author":"Morris","year":"1992","journal-title":"Magnes. 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