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Nitrate (NO3\u2212), L-arginine, L-citrulline and potassium (K+) can mitigate arterial dysfunction and stiffness by intensifying NO bioavailability. Dietary compounds such as L-arginine, L-citrulline, NO3\u2212 and K+ exert vasoactive effects as demonstrated in clinical interventions by noninvasive flow-mediated vasodilation (FMD) and pulse-wave velocity (PWV) prognostic techniques. Daily L-arginine intakes ranging from 4.5 to 21 g lead to increased FMD and reduced PWV responses. Isolated L-citrulline intake of at least 5.6 g has a better effect compared to watermelon extract, which is only effective on endothelial function when supplemented for longer than 6 weeks and contains at least 6 g of L-citrulline. NO3\u2212 supplementation employing beetroot at doses greater than 370 mg promotes hemodynamic effects through the NO3\u2212-NO2-\/NO pathway, a well-documented effect. A potassium intake of 1.5 g\/day can restore endothelial function and arterial mobility, where decreased vascular tone takes place via ATPase pump\/hyperpolarization and natriuresis, leading to muscle relaxation and NO release. These dietary interventions, alone or synergically, can ameliorate endothelial dysfunction and should be considered as adjuvant therapies in cardiovascular diseases.<\/jats:p>","DOI":"10.3390\/nu15112618","type":"journal-article","created":{"date-parts":[[2023,6,2]],"date-time":"2023-06-02T10:08:41Z","timestamp":1685700521000},"page":"2618","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["A Critical Review on Vasoactive Nutrients for the Management of Endothelial Dysfunction and Arterial Stiffness in Individuals under Cardiovascular Risk"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2839-9984","authenticated-orcid":false,"given":"Davi Vieira Teixeira","family":"da Silva","sequence":"first","affiliation":[{"name":"Instituto de Qu\u00edmica, Programa de P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancia de Alimentos e Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica, Universidade Federal do Rio de Janeiro, Av. 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