{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T21:04:44Z","timestamp":1763499884474,"version":"build-2065373602"},"reference-count":43,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T00:00:00Z","timestamp":1687737600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003197","name":"Italian Medicines Agency (AIFA)","doi-asserted-by":"publisher","award":["FARM6T9CET"],"award-info":[{"award-number":["FARM6T9CET"]}],"id":[{"id":"10.13039\/501100003197","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Diabete Ricerca","award":["FARM6T9CET"],"award-info":[{"award-number":["FARM6T9CET"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: Our aims were to evaluate the relationship of habitual legume consumption with blood pressure (BP) control in a large cohort of people with T2D and hypertension, and to investigate whether specific nutritional components of legumes or other foods may contribute to regulate BP levels. Methods: We studied 1897 participants with T2D and hypertension. Dietary habits were assessed through a validated food frequency questionnaire. Sex-specific quartiles of legume consumption were created. Results: Higher legume consumption was associated with a lower intake of energy, carbohydrates, glycaemic load, alcohol, and sodium, and a significantly greater intake of proteins, fat, monounsaturated, polyunsaturated, fibre, potassium, and polyphenols. Significantly lower systolic and diastolic BP values were observed in the highest vs. lowest quartile of legume consumption (132.9 \u00b1 6.7 vs. 137.3 \u00b1 7.0 mmHg, p &lt; 0.001; 78.9 \u00b1 4.1 vs. 81.0 \u00b1 4.2 mmHg, p = 0.002; respectively), as well as the proportion of people meeting the treatment targets (61.3% vs. 37.4% and 71.3% vs. 52.4%, respectively, p &lt; 0.01). This association was independent from other foods whose consumption is associated with the high legume intake. Conclusions: In people with T2D and hypertension, three servings of legumes per week are associated with significantly better BP control. This gives further support to current dietary guidelines in recommending the frequent consumption of legumes, as a \u201cready-to-use\u201d dietary strategy to achieve optimal BP control.<\/jats:p>","DOI":"10.3390\/nu15132895","type":"journal-article","created":{"date-parts":[[2023,6,27]],"date-time":"2023-06-27T01:49:21Z","timestamp":1687830561000},"page":"2895","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Legume Consumption and Blood Pressure Control in Individuals with Type 2 Diabetes and Hypertension: Cross-Sectional Findings from the TOSCA.IT Study"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9951-4674","authenticated-orcid":false,"given":"Marilena","family":"Vitale","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine and Surgery, Federico II University of Naples, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5799-1744","authenticated-orcid":false,"given":"Annalisa","family":"Giosu\u00e8","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine and Surgery, Federico II University of Naples, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5201-172X","authenticated-orcid":false,"given":"Sabina","family":"Sieri","sequence":"additional","affiliation":[{"name":"Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20121 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0122-8624","authenticated-orcid":false,"given":"Vittorio","family":"Krogh","sequence":"additional","affiliation":[{"name":"Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20121 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Massimino","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine and Surgery, Federico II University of Naples, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela Albarosa","family":"Rivellese","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine and Surgery, Federico II University of Naples, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Riccardi","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine and Surgery, Federico II University of Naples, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1083-1428","authenticated-orcid":false,"given":"Olga","family":"Vaccaro","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine and Surgery, Federico II University of Naples, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7848-6456","authenticated-orcid":false,"given":"Maria","family":"Masulli","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine and Surgery, Federico II University of Naples, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.cjca.2015.01.009","article-title":"Global Burden of Cardiovascular Disease and Stroke: Hypertension at the Core","volume":"31","author":"Lackland","year":"2015","journal-title":"Can. 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