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However, their impact on treatment outcomes has been poorly explored. Therefore, this transdiagnostic study is aimed at examining whether the presence of FA and\/or SU is associated with treatment outcomes in patients with different ED types. The results were not able to reveal significant differences in treatment outcomes between patients with and without FA and\/or SU; however, the effect sizes suggest higher dropout rates in the group with both FA and SU. The predictive models of treatment outcomes showed different features associated with each group. High persistence (i.e., tendency to perseverance and inflexibility) was the personality trait most associated with poor treatment outcomes in patients without addictions. High harm avoidance and younger age at ED onset were the variables most related to poor outcomes in patients with FA or SU. Finally, in the group with both addictive behaviors (FA and SU), the younger patients presented the poorest outcomes. In conclusion, our results suggest that, regardless of presenting addictive behaviors, patients with ED may similarly benefit from treatment. However, it may be important to consider the differential predictors of each group that might guide certain treatment targets.<\/jats:p>","DOI":"10.3390\/nu15132919","type":"journal-article","created":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T00:33:07Z","timestamp":1687912387000},"page":"2919","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The Role of Food Addiction and Lifetime Substance Use on Eating Disorder Treatment Outcomes"],"prefix":"10.3390","volume":"15","author":[{"given":"Romina","family":"Miranda-Olivos","sequence":"first","affiliation":[{"name":"CIBER Fisiopatolog\u00eda Obesidad y Nutrici\u00f3n (CIBERobn), Instituto de Salud Carlos III, 28029 Madrid, Spain"},{"name":"Clinical Psychology Unit, L\u2019Hospitalet de Llobregat, Hospital Universitari de Bellvitge, 08907 Barcelona, Spain"},{"name":"Psychoneurobiology of Eating and Addictive Behaviors Group, Neurosciences Programme, Bellvitge Biomedical Research Institute (IDIBELL), L\u2019Hospitalet de Llobregat, 08908 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4453-4939","authenticated-orcid":false,"given":"Zaida","family":"Ag\u00fcera","sequence":"additional","affiliation":[{"name":"CIBER Fisiopatolog\u00eda Obesidad y Nutrici\u00f3n (CIBERobn), Instituto de Salud Carlos III, 28029 Madrid, Spain"},{"name":"Psychoneurobiology of Eating and Addictive Behaviors Group, Neurosciences Programme, Bellvitge Biomedical Research Institute (IDIBELL), L\u2019Hospitalet de Llobregat, 08908 Barcelona, Spain"},{"name":"Departament d\u2019Infermeria de Salut P\u00fablica, Salut Mental i Materno-Infantil, Escola d\u2019Infermeria, Facultat de Medicina i Ci\u00e8ncies de la Salut, L\u2019Hospitalet de Llobregat, Universitat de Barcelona (UB), 08007 Barcelona, Spain"},{"name":"Research Group in Mental Health, Psychosocial and Complex Nursing Care (NURSEARCH), 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