{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:23:27Z","timestamp":1791239007342,"version":"4.1.0"},"reference-count":43,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T00:00:00Z","timestamp":1689552000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"The Precision Medicine Project","award":["2017YFC0907000"],"award-info":[{"award-number":["2017YFC0907000"]}]},{"name":"The Precision Medicine Project","award":["17"],"award-info":[{"award-number":["17"]}]},{"name":"Shanghai Municipal Education Commission-Gaofeng Discipline Development Project for Public Health and Preventive Medicine","award":["2017YFC0907000"],"award-info":[{"award-number":["2017YFC0907000"]}]},{"name":"Shanghai Municipal Education Commission-Gaofeng Discipline Development Project for Public Health and Preventive Medicine","award":["17"],"award-info":[{"award-number":["17"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>The purpose of this research was to evaluate the lipid accumulation product (LAP)\u2019s accuracy and predictive value for identifying metabolic syndrome (MS) in the general Chinese population compared with other obesity indicators. Baseline survey information from a population-based cohort study carried out in Shanghai\u2019s Songjiang District was used in this research. Odds ratios (OR) and a 95% confidence interval (CI) were obtained by logistic regression. The ability of each variable to detect MS was assessed using the receiver operating characteristic curve (ROC). The optimum cut-off point for each indicator was selected using Youden\u2019s index. The survey involved 35,446 participants in total. In both genders, the prevalence of MS rose as the LAP increased (p &lt; 0.001). The LAP\u2019s AUC was 0.901 (95%CI: 0.895\u20130.906) in males and 0.898 (95%CI: 0.893\u20130.902) in females, making it substantially more predictive of MS than other variables (BMI, WC, WHR, WHtR). The optimal cutoff point of the LAP for men and women was 36.04 (Se: 81.91%, Sp: 81.06%) and 34.95 (Se: 80.93%, Sp: 83.04%). The Youden index of the LAP was 0.64 for both sexes. Our findings imply that the LAP, compared to other obesity markers in China, is a more accurate predictor of MS.<\/jats:p>","DOI":"10.3390\/nu15143168","type":"journal-article","created":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T01:35:16Z","timestamp":1689644116000},"page":"3168","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Enhanced Predictive Value of Lipid Accumulation Product for Identifying Metabolic Syndrome in the General Population of China"],"prefix":"10.3390","volume":"15","author":[{"given":"Qi","family":"Shao","sequence":"first","affiliation":[{"name":"Key Laboratory of Public Health Safety of Ministry of Education, Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"Zhongshan Community Health Center, Shanghai 201613, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiling","family":"Wu","sequence":"additional","affiliation":[{"name":"Songjiang District Center for Disease Control and Prevention, Shanghai 201600, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Public Health Safety of Ministry of Education, Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0806-4247","authenticated-orcid":false,"given":"Na","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Public Health Safety of Ministry of Education, Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonggen","family":"Jiang","sequence":"additional","affiliation":[{"name":"Songjiang District Center for Disease Control and Prevention, Shanghai 201600, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0140-3920","authenticated-orcid":false,"given":"Qi","family":"Zhao","sequence":"additional","affiliation":[{"name":"NHC Key Laboratory of Health Technology Assessment, Department of Social Medicine, School of Public Health, Fudan University, Shanghai 200032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genming","family":"Zhao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Public Health Safety of Ministry of Education, Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,7,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1016\/S0140-6736(05)66378-7","article-title":"The metabolic syndrome","volume":"365","author":"Eckel","year":"2005","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/s40618-015-0369-5","article-title":"Lipid accumulation product and metabolic syndrome: A population-based study in northern Iran, Amol","volume":"39","author":"Motamed","year":"2016","journal-title":"J. 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