{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T22:20:25Z","timestamp":1784845225141,"version":"3.55.0"},"reference-count":32,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T00:00:00Z","timestamp":1689724800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82204038"],"award-info":[{"award-number":["82204038"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["B2022025"],"award-info":[{"award-number":["B2022025"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Scientific Research Program of Hubei Education Department","award":["82204038"],"award-info":[{"award-number":["82204038"]}]},{"name":"Scientific Research Program of Hubei Education Department","award":["B2022025"],"award-info":[{"award-number":["B2022025"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>The current study aimed to examine the association between serum selenium levels and lipids and explore whether the association was modified by diabetic status. A total of 4132 adults from the National Health and Nutrition Examination Survey (2011\u20132016) were included in this study. Multiple linear regression models were used to estimate the association between serum selenium and lipids. Higher serum selenium levels were significantly associated with increased total cholesterol (TC) (p &lt; 0.001), triglyceride (TG) (p = 0.003), and low-density lipoprotein cholesterol (LDL-C) (p = 0.003) in the overall population. Diabetic status interacted with serum selenium for TC and LDL-C (p for interaction = 0.007 and &lt;0.001). Comparing the highest with the lowest tertiles of serum selenium, the multivariate-adjusted \u03b2 coefficients (95% CIs) were 17.88 (10.89, 24.87) for TC, 13.43 (7.68, 19.18) for LDL-C among subjects without diabetes, but nonsignificant among those with diabetes. In US adults, the serum selenium was positively associated with lipids and the association was modified by diabetic status. Higher serum selenium levels were significantly associated with increased TC and LDL-C among participants without diabetes, but not among participants with diabetes.<\/jats:p>","DOI":"10.3390\/nu15143190","type":"journal-article","created":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T00:54:01Z","timestamp":1689728041000},"page":"3190","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Association between Serum Selenium Levels and Lipids among People with and without Diabetes"],"prefix":"10.3390","volume":"15","author":[{"given":"Qi","family":"Nie","sequence":"first","affiliation":[{"name":"Department of Nutrition, Hygiene and Toxicology, Academy of Nutrition and Health, School of Public Health, Medical College, Wuhan University of Science and Technology, Wuhan 430065, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changsi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Hygiene and Toxicology, Academy of Nutrition and Health, School of Public Health, Medical College, Wuhan University of Science and Technology, Wuhan 430065, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Hygiene and Toxicology, Academy of Nutrition and Health, School of Public Health, Medical College, Wuhan University of Science and Technology, Wuhan 430065, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,7,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.jacc.2004.07.001","article-title":"Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines","volume":"44","author":"Grundy","year":"2004","journal-title":"J. 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