{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T12:46:47Z","timestamp":1788266807130,"version":"build-2803163510"},"reference-count":112,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T00:00:00Z","timestamp":1693785600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Coordena\u00e7\u00e3o de Aperfeicoamento de Pessoal de N\u00edvel Superior","award":["001"],"award-info":[{"award-number":["001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Medicinal plants, such as Talisia esculenta, are rich in antioxidant biomolecules, which are used in the treatment and prevention of many diseases. The antioxidant potential of T. esculenta extracts obtained from leaves and fruit peels was investigated using biochemical and 3T3 cell line assays as well as in vivo assays using an organism model Tenebrio molitor. Four extracts were tested: hydroethanolic extracts from leaves (HF) and from fruit peels (HC), and infusion extracts from leaves (IF) and from fruit peels (IC). The biochemical assays demonstrated an antioxidant capacity verified by TAC, reducing power, DPPH, and copper chelating assays. None of the extracts exhibited cytotoxicity against 3T3 cells, instead offering a protection against CuSO4-induced oxidative stress. The antioxidant activity observed in the extracts, including their role as free radical scavengers, copper chelators, and stress protectors, was further confirmed by T. molitor assays. The CLAE-DAD analysis detected phenolic compounds, including gallic acid, rutin, and quercitrin, as the main constituents of the samples. This study highlights that leaf and fruit peels extracts of T. esculenta could be effective protectors against ROS and copper-induced stress in cellular and invertebrate models, and they should be considered as coadjutants in the treatment and prevention of diseases related to oxidative stress and for the development of natural nutraceutical products.<\/jats:p>","DOI":"10.3390\/nu15173855","type":"journal-article","created":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T10:24:30Z","timestamp":1693823070000},"page":"3855","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Exploring the Antioxidant Potential of Talisia esculenta Using In Vitro and In Vivo Approaches"],"prefix":"10.3390","volume":"15","author":[{"given":"Maria L\u00facia","family":"da Silva Cordeiro","sequence":"first","affiliation":[{"name":"Laborat\u00f3rio de Transforma\u00e7\u00e3o de Plantas e An\u00e1lise em Microscopia (LTPAM), Departamento de Biologia Celular e Gen\u00e9tica, Universidade Federal do Rio Grande do Norte (UFRN), Natal 59078-970, RN, Brazil"},{"name":"Programa de P\u00f3s-gradua\u00e7\u00e3o em Bioqu\u00edmica e Biologia Molecular, Centro de Bioci\u00eancias, Universidade Federal do Rio Grande do Norte (UFRN), Natal 59078-970, RN, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5266-9038","authenticated-orcid":false,"given":"Ver\u00f4nica Giuliani","family":"de Queiroz Aquino-Martins","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Transforma\u00e7\u00e3o de Plantas e An\u00e1lise em Microscopia (LTPAM), Departamento de Biologia Celular e Gen\u00e9tica, Universidade Federal do Rio Grande do Norte (UFRN), Natal 59078-970, RN, Brazil"},{"name":"Programa de P\u00f3s-gradua\u00e7\u00e3o em Bioqu\u00edmica e Biologia Molecular, Centro de Bioci\u00eancias, Universidade Federal do Rio Grande do Norte (UFRN), Natal 59078-970, RN, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariana Pereira","family":"da Silva","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Transforma\u00e7\u00e3o de Plantas e An\u00e1lise em Microscopia (LTPAM), Departamento de Biologia Celular e Gen\u00e9tica, Universidade Federal do Rio Grande do Norte (UFRN), Natal 59078-970, RN, Brazil"},{"name":"Programa de P\u00f3s-gradua\u00e7\u00e3o em Bioqu\u00edmica e Biologia Molecular, Centro de Bioci\u00eancias, Universidade Federal do Rio Grande do Norte (UFRN), Natal 59078-970, RN, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georggia Fatima Silva","family":"Naliato","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-gradua\u00e7\u00e3o em Bioqu\u00edmica e Biologia Molecular, Centro de Bioci\u00eancias, Universidade Federal do Rio Grande do Norte (UFRN), Natal 59078-970, RN, Brazil"},{"name":"Instituto de Medicina Tropical, Universidade Federal do Rio 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antioxidant defence grid","volume":"54","author":"Ighodaro","year":"2018","journal-title":"Alex. J. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"694","DOI":"10.3389\/fphys.2020.00694","article-title":"Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases","volume":"11","author":"Zucca","year":"2020","journal-title":"Front. Physiol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"111298","DOI":"10.1016\/j.biopha.2021.111298","article-title":"Chemopreventive effects of Melastoma malabathricum L. extract in mammary tumor model via inhibition of oxidative stress and inflammatory cytokines","volume":"137","author":"Kumar","year":"2021","journal-title":"Biomed. Pharmacother."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/s41568-021-00435-0","article-title":"The role of ROS in tumour development and progression","volume":"22","author":"Cheung","year":"2022","journal-title":"Nat. Rev. Cancer"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Alemany-Cosme, A.E., Gonz\u00e1lez, S.E., Moret, I., Mateos, B., Iborra, M., Nos, P., Sandoval, J., and Beltr\u00e1n, B. (2021). Oxidative Stress in the Pathogenesis of Crohn\u2019s Disease and the Interconnection with Immunological Response, Microbiota, External Environmental Factors, and Epigenetics. Antioxidants, 10.","DOI":"10.3390\/antiox10010064"},{"key":"ref_6","first-page":"2362","article-title":"Diabetes mellitus: A comprehensive review","volume":"8","author":"Sarkar","year":"2019","journal-title":"J. Pharmacogn. Phytochem."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Fiorelli, S., Porro, B., Cosentino, N., DI Minno, A., Manega, C.M., Fabbiocchi, F., Niccoli, G., Fracassi, F., Barbieri, S., and Marenzi, G. (2019). Activation of Nrf2\/HO-1 Pathway and Human Atherosclerotic Plaque Vulnerability: An In Vitro and In Vivo Study. Cells, 8.","DOI":"10.3390\/cells8040356"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Diaz, A., Trevi\u00f1o, S., Pulido-Fernandez, G., Mart\u00ednez-Mu\u00f1oz, E., Cervantes, N., Espinosa, B., Rojas, K., P\u00e9rez-Severiano, F., Montes, S., and Rubio-Osornio, M. (2019). Epicatechin Reduces Spatial Memory Deficit Caused by Amyloid-\u03b225\u201335 Toxicity Modifying the Heat Shock Proteins in the CA1 Region in the Hippocampus of Rats. Antioxidants, 8.","DOI":"10.3390\/antiox8050113"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Correia, A.S., Cardoso, A., and Vale, N. (2023). Oxidative Stress in Depression: The Link with the Stress Response, Neuroinflammation, Serotonin, Neurogenesis and Synaptic Plasticity. Antioxidants, 12.","DOI":"10.3390\/antiox12020470"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Divekar, P.A., Narayana, S., Divekar, B.A., Kumar, R., Gadratagi, B.G., Ray, A., Singh, A.K., Rani, V., Singh, V., and Singh, A.K. (2022). Plant Secondary Metabolites as Defense Tools against Herbivores for Sustainable Crop Protection. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23052690"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"39","DOI":"10.2174\/1872213X12666180115153635","article-title":"Anti-Inflammatory Drugs and Herbs with Special Emphasis on Herbal Medicines for Countering Inflammatory Diseases and Disorders\u2014A Review","volume":"12","author":"Yatoo","year":"2018","journal-title":"Recent Pat. Inflamm. Allergy Drug Discov."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"8648742","DOI":"10.1155\/2020\/8648742","article-title":"Identifying Plant-Based Natural Medicine against Oxidative Stress and Neurodegenerative Disorders","volume":"2020","author":"Chandran","year":"2020","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"9364364","DOI":"10.1155\/2018\/9364364","article-title":"Terminalia bellirica (Gaertn.) Roxb. Extract and Gallic Acid Attenuate LPS-Induced Inflammation and Oxidative Stress via MAPK\/NF-\u03baB and Akt\/AMPK\/Nrf2 Pathways","volume":"2018","author":"Tanaka","year":"2018","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1016\/j.redox.2020.101474","article-title":"Anthocyanin supplementation improves anti-oxidative and anti-inflammatory capacity in a dose-response manner in subjects with dyslipidemia","volume":"32","author":"Zhang","year":"2020","journal-title":"Redox Biol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"6037303","DOI":"10.1155\/2022\/6037303","article-title":"Resveratrol Treats UVB-Induced Photoaging by Anti-MMP Expression, through Anti-Inflammatory, Antioxidant, and Antiapoptotic Properties, and Treats Photoaging by Upregulating VEGF-B Expression","volume":"2022","author":"Cui","year":"2022","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"7904349","DOI":"10.1155\/2018\/7904349","article-title":"Biological Efficacy of Medicinal Plant Extracts in Preventing Oxidative Damage","volume":"2018","author":"Banerjee","year":"2018","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Proestos, C. (2020). The Benefits of Plant Extracts for Human Health. Foods, 9.","DOI":"10.3390\/foods9111653"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s11240-017-1332-2","article-title":"Secondary metabolism of pharmaceuticals in the plant in vitro cultures: Strategies, approaches, and limitations to achieving higher yield","volume":"132","author":"Isah","year":"2018","journal-title":"Plant Cell Tissue Organ Cult."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Heinrich, M., Mah, J., and Amirkia, V. (2021). Alkaloids Used as Medicines: Structural Phytochemistry Meets Biodiversity-An Update and Forward Look. Molecules, 26.","DOI":"10.3390\/molecules26071836"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1089\/jmf.2018.0010","article-title":"Biological Characterization of an Edible Species from Brazilian Biodiversity: From Pharmacognostic Data to Ethnopharmacological Investigation","volume":"21","author":"Tirloni","year":"2018","journal-title":"J. Med. Food"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"127929","DOI":"10.1016\/j.foodchem.2020.127929","article-title":"Mass spectrometry characterization, antioxidant activity, and cytotoxicity of the peel and pulp extracts of Pitomba","volume":"340","author":"Fraga","year":"2021","journal-title":"Food Chem."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"272749","DOI":"10.1155\/2012\/272749","article-title":"Etnofarmacologia de Plantas Medicinais da Regi\u00e3o do Pantanal (Mato Grosso, Brasil)","volume":"2012","author":"Bieski","year":"2012","journal-title":"Evid.-Based Complement. Altern. Med."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1590\/1809-4392201400423","article-title":"Etnobot\u00e2nica de plantas medicinais em comunidades ribeirinhas do Munic\u00edpio de Manacapuru, Amazonas, Brasil","volume":"44","year":"2014","journal-title":"Acta Amaz."},{"key":"ref_24","first-page":"1","article-title":"Uso de giberelinas na emerg\u00eancia de pl\u00e2ntulas de Talisia esculenta (A. St. Hil.) Radlk","volume":"4","author":"Vieira","year":"2006","journal-title":"Rev. Cient\u00edfica Eletr\u00f4nica Eng. Florest."},{"key":"ref_25","first-page":"1","article-title":"Frutos da Caatinga de Sergipe utilizados na alimenta\u00e7\u00e3o humana","volume":"8","author":"Santos","year":"2012","journal-title":"Sci. Plena"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Costanzo, G., Vitale, E., Iesce, M.R., Naviglio, D., Amoresano, A., Fontanarosa, C., Spinelli, M., Ciaravolo, M., and Arena, C. (2022). Antioxidant Properties of Pulp, Peel and Seeds of Phlegrean Mandarin (Citrus reticulata Blanco) at Different Stages of Fruit Ripening. Antioxidants, 11.","DOI":"10.3390\/antiox11020187"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"5988","DOI":"10.1080\/14786419.2020.1810034","article-title":"Jabuticaba [Plinia peruviana (Poir.) Govaerts]: A Brazilian fruit with a promising application against itraconazole-susceptible and -resistant Sporothrix brasiliensis","volume":"35","author":"Waller","year":"2021","journal-title":"Nat. Prod. Res."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Castangia, I., Manca, M.L., Allaw, M., Hellstr\u00f6m, J., Granato, D., and Manconi, M. (2021). Jabuticaba (Myrciaria jaboticaba) Peel as a Sustainable Source of Anthocyanins and Ellagitannins Delivered by Phospholipid Vesicles for Alleviating Oxidative Stress in Human Keratinocytes. Molecules, 26.","DOI":"10.3390\/molecules26216697"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"112049","DOI":"10.1016\/j.biopha.2021.112049","article-title":"Antioxidant compounds from Annona crassiflora fruit peel reduce lipid levels and oxidative damage and maintain the glutathione defense in hepatic tissue of Triton WR-1339-induced hyperlipidemic mice","volume":"142","author":"Ramos","year":"2021","journal-title":"Biomed. Pharmacother."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"3507","DOI":"10.1007\/s00216-018-0854-8","article-title":"Analysis of phenolic compounds in different parts of pomegranate (Punica granatum) fruit by HPLC-PDA-ESI\/MS and evaluation of their antioxidant activity: Application to different Italian varieties","volume":"410","author":"Russo","year":"2018","journal-title":"Anal. Bioanal. Chem."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"125229","DOI":"10.1016\/j.ijbiomac.2023.125229","article-title":"Eco-friendly simultaneous extraction of pectins and phenolics from passion fruit (Passiflora edulis Sims) peel: Process optimization, physicochemical properties, and antioxidant activity","volume":"243","author":"Huo","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"6141","DOI":"10.2174\/1381612811319340008","article-title":"Tea and health: Studies in humans","volume":"19","author":"Khan","year":"2013","journal-title":"Curr. Pharm. Des."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1007\/s11130-019-00750-w","article-title":"Herbal Teas and their Health Benefits: A Scoping Review","volume":"74","author":"Poswal","year":"2019","journal-title":"Plant Foods Hum. Nutr."},{"key":"ref_34","first-page":"1108","article-title":"Determination of the Antioxidant Capacity of Red Fruits by Miniaturized Spectrophotometry Assays","volume":"30","author":"Becker","year":"2019","journal-title":"J. Braz. Chem. Soc."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"507887","DOI":"10.3389\/fchem.2020.507887","article-title":"Extraction of Flavonoids From Natural Sources Using Modern Techniques","volume":"8","author":"Chaves","year":"2020","journal-title":"Front. Chem."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"2573580","DOI":"10.1155\/2016\/2573580","article-title":"Antioxidant, Cytotoxic, and Antiproliferative Activities and Total Polyphenol Contents of the Extracts of Geissospermum reticulatum Bark","volume":"2016","author":"Kozielewicz","year":"2016","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.jep.2010.04.018","article-title":"Antioxidant properties of Baccharis trimera in the neutrophils of Fisher rats","volume":"129","author":"Silva","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Aquino-Martins, V.G.Q., De Melo, L.F.M., Silva, L.M.P., Targino, L.T.R., Queiroz, M.F., Viana, R.L.S., Zucolotto, S.M., Andrade, V.S., Rocha, H.A.O., and Scortecci, K.C. (2019). Antioxidante In Vitro, Anti-Biofilme e Atividades de Prote\u00e7\u00e3o Solar do Extrato de Polpa de Melocactus zehntneri (Britton & Rose). Antioxidantes, 8.","DOI":"10.3390\/antiox8100439"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.ijbiomac.2022.05.077","article-title":"Protective potential of sulfated polysaccharides from tropical seaweeds against alkylating- and oxidizing-induced genotoxicity","volume":"211","author":"Pessatti","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","article-title":"Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays","volume":"65","author":"Mosmann","year":"1983","journal-title":"J. Immunol. Methods"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Moghadam, S.E., Moridi Farimani, M., Soroury, S., Ebrahimi, S.N., Jabbarzadeh, E., and Hypermongone, C. (2022). Accelerates Wound Healing through the Modulation of Inflammatory Factors and Promotion of Fibroblast Migration. Molecules, 24.","DOI":"10.3390\/molecules24102022"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3389\/fcell.2019.00107","article-title":"In vitro Cell Migration, Invasion, and Adhesion Assays: From Cell Imaging to Data Analysis","volume":"7","author":"Pijuan","year":"2019","journal-title":"Front. Cell Dev. Biol."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Presa, F.B., Marques, M.L.M., Viana, R.L.S., Nobre, L.T.D.B., Costa, L.S., and Rocha, H.A.O. (2018). The Protective Role of Sulfated Polysaccharides from Green Seaweed Udotea flabellum in Cells Exposed to Oxidative Damage. Mar. Drugs, 16.","DOI":"10.3390\/md16040135"},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Silva, T.F., Cavalcanti Filho, J.R.N., Barreto Fons\u00eaca, M.M.L., Santos, N.M.D., Da Silva, A.C.B., Zagmignan, A., Abreu, A.G., Da Silva, A.P.S., Lima, V.L.D.M., and Silva, N.H.D. (2020). Products Derived from Buchenavia tetraphylla Leaves Have In Vitro Antioxidant Activity and Protect Tenebrio molitor Larvae against Escherichia coli-Induced Injury. Pharmaceuticals, 13.","DOI":"10.3390\/ph13030046"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1007\/s00203-017-1441-7","article-title":"Effect of Lactobacillus rhamnosus on the response of Galleria mellonella against Staphylococcus aureus and Escherichia coli infections","volume":"200","author":"Jorge","year":"2018","journal-title":"Arch. Microbiol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/j.fct.2006.01.011","article-title":"Antiproliferative and antioxidant properties of an enzymatic hydrolysate from brown alga, Ecklonia cava","volume":"44","author":"Athukorala","year":"2006","journal-title":"Food Chem. Toxicol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.indcrop.2015.03.010","article-title":"Phytochemical analysis and antioxidant activities of Lantana camara and Lantana montevidensis extracts","volume":"70","author":"Sousa","year":"2015","journal-title":"Ind. Crops Prod."},{"key":"ref_48","first-page":"3928706","article-title":"Coccoloba alnifolia Leaf Extract as a Potential Antioxidant Molecule Using In Vitro and In Vivo Assays","volume":"2020","author":"Gomes","year":"2020","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"3043720","DOI":"10.1155\/2021\/3043720","article-title":"Antioxidant Activities of Commiphora leptophloeos (Mart.) J. B. Gillett (Burseraceae) Leaf Extracts Using In Vitro and In Vivo Assays","volume":"2021","author":"Cordeiro","year":"2021","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Munteanu, I.G., and Apetrei, C. (2021). Analytical Methods Used in Determining Antioxidant Activity: A Review. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms22073380"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1080\/87559120802304269","article-title":"In Vitro Methods of Assay of Antioxidants: An Overview","volume":"24","author":"Sudhakar","year":"2008","journal-title":"Food Rev. Int."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1038\/sj.bjp.0705776","article-title":"Measuring reactive species and oxidative damage in vivo and in cell culture: How should you do it and what do the results mean?","volume":"142","author":"Halliwell","year":"2004","journal-title":"Br. J. Pharmacol."},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Mendon\u00e7a, J.D.S., Guimar\u00e3es, R.C.A., Zorgetto-Pinheiro, V.A., Fernandes, C.D.P., Marcelino, G., Bogo, D., Freitas, K.C., Hiane, P.A., de P\u00e1dua, M.E.S., and Vilela, M.L.B. (2022). Natural Antioxidant Evaluation: A Review of Detection Methods. Molecules, 27.","DOI":"10.3390\/molecules27113563"},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Senoner, T., and Dichtl, W. (2019). Oxidative stress in cardiovascular diseases: Still a Therapeutic target?. Nutrients, 9.","DOI":"10.3390\/nu11092090"},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Teleanu, D.M., Niculescu, A.-G., Lungu, I.I., Radu, C.I., Vlad\u00e2cenco, O., Roza, E., Cost\u0103chescu, B., Grumezescu, A.M., and Teleanu, R.I. (2022). An Overview of Oxidative Stress, Neuroinflammation, and Neurodegenerative Diseases. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23115938"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.tips.2017.04.005","article-title":"Targeting Free Radicals in Oxidative Stress-Related Human Diseases","volume":"38","author":"Poprac","year":"2017","journal-title":"Trends Pharmacol. Sci."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1038\/s41573-021-00233-1","article-title":"Targeting oxidative stress in disease: Promise and limitations of antioxidant therapy","volume":"20","author":"Forman","year":"2021","journal-title":"Nat. Rev. Drug Discov."},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Guerriero, G., Berni, R., Mu\u00f1oz-Sanchez, J.A., Apone, F., Abdel-Salam, E.M., Qahtan, A.A., Alatar, A.A., Cantini, C., Cai, G., and Hausman, J.-F. (2018). Production of Plant Secondary Metabolites: Examples, Tips and Suggestions for Biotechnologists. Genes, 9.","DOI":"10.3390\/genes9060309"},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Koch, W., Zag\u00f3rska, J., Marzec, Z., and Kukula-Koch, W. (2019). Applications of Tea (Camellia sinensis) and its Active Constituents in Cosmetics. Molecules, 24.","DOI":"10.3390\/molecules24234277"},{"key":"ref_60","doi-asserted-by":"crossref","unstructured":"Ferreira-Santos, P., Ibarz, R., Fernandes, J.-M., Pinheiro, A.C., Botelho, C., Rocha, C.M.R., Teixeira, J.A., and Mart\u00edn-Belloso, O. (2021). Extrato Polifen\u00f3lico da Casca de Pinheiro Encapsulado durante a Digest\u00e3o Gastrointestinal: Bioacessibilidade, Bioatividade e Preven\u00e7\u00e3o do Estresse Oxidativo. Foods, 10.","DOI":"10.3390\/foods10020328"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s12970-018-0218-y","article-title":"Herbal medicine for sports: A review","volume":"15","author":"Sellami","year":"2018","journal-title":"J. Int. Soc. Sports Nutr."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"3090","DOI":"10.1039\/C9FO00580C","article-title":"Let food be your medicine: Nutraceutical properties of lycopene","volume":"10","author":"Grabowska","year":"2019","journal-title":"Food Funct."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"e14387","DOI":"10.1111\/jfbc.14387","article-title":"Role of Medicinal plant-derived Nutraceuticals as a potential target for the treatment of breast cancer","volume":"46","author":"Alharbi","year":"2022","journal-title":"J. Food Biochem."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/s41573-020-00114-z","article-title":"Natural products in drug discovery: Advances and opportunities","volume":"20","author":"Atanasov","year":"2021","journal-title":"Nat. Rev. Drug Discov."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.carbpol.2019.01.073","article-title":"Antiproliferative xylan from corn cobs induces apoptosis in tumor cells","volume":"210","author":"Viana","year":"2019","journal-title":"Carbohydr. Polym."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"e13175","DOI":"10.1111\/jfbc.13175","article-title":"Evaluation of the in vitro \u237a-amylase inhibitory, antiglycation, and antioxidant properties of Punica granatum L. (pomegranate) fruit peel acetone extract and its effect on glucose uptake and oxidative stress in hepatocytes","volume":"44","author":"Chukwuma","year":"2020","journal-title":"J. Food Biochem."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"1730492","DOI":"10.1155\/2020\/1730492","article-title":"Antidiabetic Potency, Antioxidant Effects, and Mode of Actions of Citrus reticulata Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin in Nicotinamide\/Streptozotocin-Induced Wistar Diabetic Rats","volume":"2020","author":"Ali","year":"2020","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"112120","DOI":"10.1016\/j.biopha.2021.112120","article-title":"Pea (Pisum sativum) peel extract attenuates DOX-induced oxidative myocardial injury","volume":"143","author":"Abdelghffar","year":"2021","journal-title":"Biomed. Pharmacother."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1016\/j.biopha.2018.04.186","article-title":"Antioxidant mechanism of polyphenol-rich Nymphaea nouchali leaf extract protecting DNA damage and attenuating oxidative stress-induced cell death via Nrf2-mediated heme-oxygenase-1 induction coupled with ERK\/p38 signaling pathway","volume":"103","author":"Bajpai","year":"2018","journal-title":"Biomed. Pharmacother."},{"key":"ref_70","doi-asserted-by":"crossref","unstructured":"Jantapaso, H., and Mittraparp-Arthorn, P. (2022). Phytochemical Composition and Bioactivities of Aqueous Extract of Rambutan (Nephelium lappaceum L. cv. Rong Rian) Peel. Antioxidants, 11.","DOI":"10.3390\/antiox11050956"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.jsps.2023.02.006","article-title":"In vitro anti-ageing activities of ethanolic extracts from Pink rambutan (Nephelium lappaceum Linn.) for skin applications","volume":"31","author":"Boonpisuttinant","year":"2023","journal-title":"Saudi Pharm. J."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"981978","DOI":"10.3389\/fphar.2022.981978","article-title":"Understanding plant to extract ratios in botanical extracts","volume":"13","author":"Monagas","year":"2022","journal-title":"Front. Pharmacol."},{"key":"ref_73","doi-asserted-by":"crossref","unstructured":"Christodoulou, M.C., Orellana, P.J.C., Hesami, G., Jafarzadeh, S., Lorenzo, J.M., Dom\u00ednguez, R., Moreno, A., and Hadidi, M. (2022). Spectrophotometric Methods for Measurement of Antioxidant Activity in Food and Pharmaceuticals. Antioxidants, 11.","DOI":"10.3390\/antiox11112213"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"1007310","DOI":"10.3389\/fphar.2022.1007310","article-title":"Phytochemical and toxicological evaluation of Zephyranthes citrina","volume":"13","author":"Rehman","year":"2022","journal-title":"Front. Pharmacol."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.jphotobiol.2016.12.033","article-title":"Photochemoprotective effects against UVA and UVB irradiation and photosafety assessment of Litchi chinensis leaves extract","volume":"167","author":"Thiesen","year":"2017","journal-title":"J. Photochem. Photobiol. B"},{"key":"ref_76","first-page":"1359164","article-title":"Copper Induces Oxidative Stress and Apoptosis in the Mouse Liver","volume":"2020","author":"Liu","year":"2020","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.tiv.2018.10.017","article-title":"Copper induces oxidative stress and apoptosis through mitochondria-mediated pathway in chicken hepatocytes","volume":"54","author":"Yang","year":"2019","journal-title":"Toxicol. Vitr."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"112587","DOI":"10.1016\/j.ecoenv.2021.112587","article-title":"Copper exposure induces mitochondrial dynamic disorder and oxidative stress via mitochondrial unfolded protein response in pig fundic gland","volume":"223","author":"Huo","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_79","doi-asserted-by":"crossref","unstructured":"Zhang, P., Liu, N., Xue, M., Zhang, M., Liu, W., Xu, C., F\u00e3, Y., Meng, Y., Zhang, Q., and Zhou, Y. (2023). Anti-Inflammatory and Antioxidant Properties of \u03b2-Sitosterol in Copper Sulfate-Induced Inflammation in Zebrafish (Danio rerio). Antioxidants, 12.","DOI":"10.3390\/antiox12020391"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"7417","DOI":"10.1038\/s41598-021-86477-8","article-title":"Oxida\u00e7\u00e3o de ascorbato por ferro, cobre e esp\u00e9cies reativas de oxig\u00eanio: Revis\u00e3o, desenvolvimento de modelo e deriva\u00e7\u00e3o de constantes de taxa chave","volume":"11","author":"Shen","year":"2021","journal-title":"Sci. Rep."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"mfad040","DOI":"10.1093\/mtomcs\/mfad040","article-title":"Revisiting the pro-oxidant activity of copper: Interplay of ascorbate, cysteine, and glutathione","volume":"15","author":"Falcone","year":"2023","journal-title":"Metallomics"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1152\/ajpcell.00132.2018","article-title":"Copper transporters and copper chaperones: Roles in cardiovascular physiology and disease","volume":"315","author":"Fukai","year":"2018","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1039\/C8MT00219C","article-title":"Is copper a new target to counteract the progression of chronic diseases?","volume":"10","author":"Balsano","year":"2018","journal-title":"Metallomics"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1007\/s00424-020-02412-2","article-title":"The molecular mechanisms of copper metabolism and its roles in human diseases","volume":"472","author":"Chen","year":"2020","journal-title":"Pfl\u00fcgers Arch.-Eur. J. Physiol."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"mfac018","DOI":"10.1093\/mtomcs\/mfac018","article-title":"Copper-mediated \u03b2-amyloid toxicity and its chelation therapy in Alzheimer\u2019s disease","volume":"14","author":"Singh","year":"2022","journal-title":"Metallomics"},{"key":"ref_86","doi-asserted-by":"crossref","unstructured":"Jiang, R., Sui, Y., Hong, J., Niimi, M., Yan, Q., Shi, Z., and Yao, J. (2023). The Combined Administration of Vitamin C and Copper Induces a Systemic Oxidative Stress and Kidney Injury. Biomolecules, 13.","DOI":"10.3390\/biom13010143"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.2174\/0929867053764635","article-title":"Metals, toxicity and oxidative stress","volume":"12","author":"Valko","year":"2005","journal-title":"Curr. Med. Chem."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1007\/s10534-016-9942-4","article-title":"The neurotoxicity of iron, copper and cobalt in Parkinson\u2019s disease through ROS-mediated mechanisms","volume":"29","author":"Lan","year":"2016","journal-title":"Biometals"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1161\/CIRCRESAHA.117.311401","article-title":"Reactive Oxygen Species in Metabolic and Inflammatory Signaling","volume":"122","author":"Forrester","year":"2018","journal-title":"Circ. Res."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"3879","DOI":"10.1007\/s11010-021-04193-3","article-title":"Quercetin improves oxidative stress-induced pancreatic beta cell alterations via mTOR-signaling","volume":"476","author":"Dhanya","year":"2021","journal-title":"Mol. Cell. Biochem."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1177\/0960327110389837","article-title":"Paullinia cupana Mart. var. Sorbilis protects human dopaminergic neuroblastoma SH-SY5Y cell line against rotenone-induced cytotoxicity","volume":"30","author":"Barreto","year":"2011","journal-title":"Hum. Exp. Toxicol."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.fct.2017.01.022","article-title":"Protective effects of rambutan (Nephelium lappaceum) peel phenolics on H2O2-induced oxidative damages in HepG2 cells and d-galactose-induced aging mice","volume":"108","author":"Zhuang","year":"2017","journal-title":"Food Chem. Toxicol."},{"key":"ref_93","doi-asserted-by":"crossref","unstructured":"De Souza, P.C., Caloni, C.C., Wilson, D., and Almeida, R.S. (2018). An Invertebrate Host to Study Fungal Infections, Mycotoxins and Antifungal Drugs: Tenebrio molitor. J. Fungi, 4.","DOI":"10.3390\/jof4040125"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1093\/mmy\/myy042","article-title":"Galleria mellonella as a model system to study virulence potential of mucormycetes and evaluation of antifungal treatment","volume":"57","author":"Maurer","year":"2019","journal-title":"J. Med. Mycol."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.2147\/IDR.S312553","article-title":"Tenebrio molitor as an Alternative Model to Analyze the Sporothrix Species Virulence","volume":"14","year":"2021","journal-title":"Infect. Drug Resist."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.3389\/fmicb.2018.02211","article-title":"A Model for Trans-Kingdom Pathogenicity in Fonsecaea Agents of Human Chromoblastomycosis","volume":"9","author":"Fornari","year":"2018","journal-title":"Front. Microbiol."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1007\/s42770-022-00771-9","article-title":"A chloroacetamide derivative as a potent candidate for fusariosis treatment","volume":"53","author":"Machado","year":"2022","journal-title":"Braz. J. Microbiol."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"e06985320","DOI":"10.33448\/rsd-v9i8.5320","article-title":"Evaluation of antioxidating activity of tea maked in free fairs and industrialized tea in San Lu\u00eds-Maranh\u00e3o","volume":"9","author":"Azevedo","year":"2020","journal-title":"Braz. Res. Soc. Dev."},{"key":"ref_99","doi-asserted-by":"crossref","unstructured":"Brai, A., Poggialini, F., Vagaggini, C., Pasqualini, C., Simoni, S., Francardi, V., and Dreassi, E. (2023). Tenebrio molitor as a Simple and Cheap Preclinical Pharmacokinetic and Toxicity Model. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24032296"},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1007\/s10534-021-00341-w","article-title":"Copper and zinc impact on stress biomarkers and growth parameters in a model organism, Galleria mellonella larvae","volume":"34","author":"Coskun","year":"2021","journal-title":"Biometals"},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1007\/s10646-022-02531-9","article-title":"Effects of Cu, Zn and their mixtures on bioaccumulation and antioxidant enzyme activities in Galleria mellonella L. (Lepidoptera: Pyralidae)","volume":"31","author":"Mese","year":"2022","journal-title":"Ecotoxicology"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s00128-018-2529-8","article-title":"E Oxide Nanoparticles on Tissue Accumulation and Antioxidant Enzymes of Galleria mellonella L","volume":"102","author":"Tuncsoy","year":"2019","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0162-0134(02)00511-1","article-title":"Iron and copper chelation by flavonoids: An electrospray mass spectrometry study","volume":"92","author":"Fernandez","year":"2002","journal-title":"J. Inorg. Biochem."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"e13394","DOI":"10.1111\/jfbc.13394","article-title":"Concept, mechanism, and applications of phenolic antioxidants in foods","volume":"44","author":"Zeb","year":"2020","journal-title":"J. Food Biochem."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"S335","DOI":"10.3233\/JAD-200185","article-title":"Polyphenols as Potential Metal Chelation Compounds against Alzheimer\u2019s Disease","volume":"82","author":"Burillo","year":"2021","journal-title":"J. Alzheimers Dis."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"5893","DOI":"10.1021\/acs.jafc.6b02255","article-title":"In Vitro Antioxidant-Activity Evaluation of Gallic-Acid-Grafted Chitosan Conjugate Synthesized by Free-Radical-Induced Grafting Method","volume":"64","author":"Hu","year":"2016","journal-title":"J. Agric. Food Chem."},{"key":"ref_107","doi-asserted-by":"crossref","unstructured":"Truong, V.L., Ko, S.Y., Jun, M., and Jeong, W.S. (2016). Quercitrin from Toona sinensis (Juss.) M.Roem. Attenuates Acetaminophen-Induced Acute Liver Toxicity in HepG2 Cells and Mice through Induction of Antioxidant Machinery and Inhibition of Inflammation. Nutrients, 8.","DOI":"10.3390\/nu8070431"},{"key":"ref_108","doi-asserted-by":"crossref","unstructured":"Sachetto, A.T.A., Rosa, J.G., and Santoro, M.L. (2018). Rutin (quercetin-3-rutinoside) modulates the hemostatic disturbances and redox imbalance induced by Bothrops jararaca snake venom in mice. PLoS Neglected Trop. Dis., 12.","DOI":"10.1371\/journal.pntd.0006774"},{"key":"ref_109","doi-asserted-by":"crossref","unstructured":"Choi, S.S., Park, H.R., and Lee, K.A. (2021). A Comparative Study of Rutin and Rutin Glycoside: Antioxidant Activity, Anti-Inflammatory Effect, Effect on Platelet Aggregation and Blood Coagulation. Antioxidants, 10.","DOI":"10.3390\/antiox10111696"},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"813890","DOI":"10.3389\/fimmu.2021.813890","article-title":"Gallic Acid Alleviates Gut Dysfunction and Boosts Immune and Antioxidant Activities in Puppies Under Environmental Stress Based on Microbiome-Metabolomics Analysis","volume":"12","author":"Yang","year":"2022","journal-title":"Front. Immunol."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.foodres.2016.01.031","article-title":"Phenolic and aroma compositions of pitomba fruit (Talisia esculenta Radlk.) assessed by LC\u2013MS\/MS and HS-SPME\/GC\u2013MS","volume":"83","author":"Bataglion","year":"2016","journal-title":"Food Res. Int."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"3987","DOI":"10.1007\/s12649-019-00723-9","article-title":"Improvement of Phenolic Contents and Antioxidant Activities of Longan (Dimocarpus longan) Peel Extracts by Enzymatic Treatment","volume":"11","author":"Rakariyatham","year":"2020","journal-title":"Waste Biomass Valorization"}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/15\/17\/3855\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T20:46:12Z","timestamp":1760129172000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/15\/17\/3855"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,4]]},"references-count":112,"journal-issue":{"issue":"17","published-online":{"date-parts":[[2023,9]]}},"alternative-id":["nu15173855"],"URL":"https:\/\/doi.org\/10.3390\/nu15173855","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,4]]}}}