{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T20:20:45Z","timestamp":1771878045850,"version":"3.50.1"},"reference-count":32,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T00:00:00Z","timestamp":1693958400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>We sought to examine body composition using bioimpedance analysis in patients with metabolic dysfunction-associated fatty liver disease (MAFLD, 2014 males and 949 females). Factors linked to the fat-free mass index (FF index) were examined using univariate and multivariate analysis. An FF index &lt; 18 kg\/m2 in males and an FF index &lt; 15 kg\/m2 in females were defined as having decreased skeletal muscle mass. The median age and body mass index (BMI) were 55 years and 25.4 kg\/m2 in males, and 57 years and 25.4 kg\/m2 in females, respectively. The FF index strongly correlated with muscle mass index both in males (r = 0.999) and females (r = 0.999). The prevalence of patients with an FF index &lt; 18 kg\/m2 in males and an FF index &lt; 15 kg\/m2 in females was well stratified according to age, BMI, severity of FL, and FIB4 index. In the males, in the multivariate analysis, BMI (p &lt; 0.0001), fat mass index (p &lt; 0.0001), and waist circumference (p = 0.0050) were found to be significant factors linked to FF index. In the females, in the multivariate analysis, BMI (p &lt; 0.0001) and fat mass index (p &lt; 0.0001) were found to be significant. In conclusion, fat accumulation as reflected by BMI, which is an easily available marker, could be a useful indicator for the skeletal muscle mass in MAFLD.<\/jats:p>","DOI":"10.3390\/nu15183878","type":"journal-article","created":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T10:23:42Z","timestamp":1693995822000},"page":"3878","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Body Composition Analysis in Patients with Metabolic Dysfunction-Associated Fatty Liver Disease"],"prefix":"10.3390","volume":"15","author":[{"given":"Saori","family":"Onishi","sequence":"first","affiliation":[{"name":"Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Takatsukishi 569-8686, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Fukuda","sequence":"additional","affiliation":[{"name":"Health Science Clinic, Osaka Medical and Pharmaceutical University, Takatsuki 569-8686, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5211-4021","authenticated-orcid":false,"given":"Masahiro","family":"Matsui","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Takatsukishi 569-8686, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kosuke","family":"Ushiro","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Takatsukishi 569-8686, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiro","family":"Nishikawa","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Takatsukishi 569-8686, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2915-7875","authenticated-orcid":false,"given":"Akira","family":"Asai","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Takatsukishi 569-8686, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo Ki","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Kobe Asahi Hospital, Kobe 653-8501, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Nishikawa","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Takatsukishi 569-8686, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.jamda.2019.12.012","article-title":"Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment","volume":"21","author":"Chen","year":"2020","journal-title":"J. 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