{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:52:19Z","timestamp":1790859139127,"version":"4.1.0"},"reference-count":122,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T00:00:00Z","timestamp":1695859200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Central Public-interest Scientific Institution Basal Research Fund","award":["1610172022007"],"award-info":[{"award-number":["1610172022007"]}]},{"name":"Central Public-interest Scientific Institution Basal Research Fund","award":["Y2023XK04"],"award-info":[{"award-number":["Y2023XK04"]}]},{"name":"Central Public-interest Scientific Institution Basal Research Fund","award":["2023-NK-145"],"award-info":[{"award-number":["2023-NK-145"]}]},{"name":"Central Public-interest Scientific Institution Basal Research Fund","award":["HB2022C14"],"award-info":[{"award-number":["HB2022C14"]}]},{"name":"Central Public-interest Scientific Institution Basal Research Fund","award":["1610172022007"],"award-info":[{"award-number":["1610172022007"]}]},{"name":"Central Public-interest Scientific Institution Basal Research Fund","award":["Y2023XK04"],"award-info":[{"award-number":["Y2023XK04"]}]},{"name":"Central Public-interest Scientific Institution Basal Research Fund","award":["2023-NK-145"],"award-info":[{"award-number":["2023-NK-145"]}]},{"name":"Central Public-interest Scientific Institution Basal Research Fund","award":["HB2022C14"],"award-info":[{"award-number":["HB2022C14"]}]},{"name":"the Talented Scientist Project of Qinghai Province","award":["1610172022007"],"award-info":[{"award-number":["1610172022007"]}]},{"name":"the Talented Scientist Project of Qinghai Province","award":["Y2023XK04"],"award-info":[{"award-number":["Y2023XK04"]}]},{"name":"the Talented Scientist Project of Qinghai Province","award":["2023-NK-145"],"award-info":[{"award-number":["2023-NK-145"]}]},{"name":"the Talented Scientist Project of Qinghai Province","award":["HB2022C14"],"award-info":[{"award-number":["HB2022C14"]}]},{"name":"Chinese Academy of Engineering cooperation project","award":["1610172022007"],"award-info":[{"award-number":["1610172022007"]}]},{"name":"Chinese Academy of Engineering cooperation project","award":["Y2023XK04"],"award-info":[{"award-number":["Y2023XK04"]}]},{"name":"Chinese Academy of Engineering cooperation project","award":["2023-NK-145"],"award-info":[{"award-number":["2023-NK-145"]}]},{"name":"Chinese Academy of Engineering cooperation project","award":["HB2022C14"],"award-info":[{"award-number":["HB2022C14"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Selenium is an essential micronutrient that plays a crucial role in maintaining human health. Selenium deficiency is seriously associated with various diseases such as Keshan disease, Kashin\u2013Beck disease, cataracts, and others. Conversely, selenium supplementation has been found to have multiple effects, including antioxidant, anti-inflammatory, and anticancer functions. Compared with inorganic selenium, organic selenium exhibits higher bioactivities and a wider range of safe concentrations. Consequently, there has been a significant development of selenium-enriched foods which contain large amounts of organic selenium in order to improve human health. This review summarizes the physiological role and metabolism of selenium, the development of selenium-enriched foods, the physiological functions of selenium-enriched foods, and provides an analysis of total selenium and its species in selenium-enriched foods, with a view to laying the foundation for selenium-enriched food development.<\/jats:p>","DOI":"10.3390\/nu15194189","type":"journal-article","created":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T07:50:26Z","timestamp":1695887426000},"page":"4189","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":86,"title":["Research Progress of Selenium-Enriched Foods"],"prefix":"10.3390","volume":"15","author":[{"given":"Zhenna","family":"Chen","sequence":"first","affiliation":[{"name":"Key Laboratory of Biology and Genetic Improvement of Oil Crops, Oil Crops Research Institute of Chinese Academy of Agricultural Sciences, Ministry of Agriculture and Rural Affairs, Wuhan 430062, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiqing","family":"Lu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Biology and Genetic Improvement of Oil Crops, Oil Crops Research Institute of Chinese Academy of Agricultural Sciences, Ministry of Agriculture and Rural Affairs, Wuhan 430062, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoling","family":"Dun","sequence":"additional","affiliation":[{"name":"Key Laboratory of Biology and Genetic Improvement of Oil Crops, Oil Crops Research Institute of Chinese Academy of Agricultural Sciences, Ministry of Agriculture and Rural Affairs, Wuhan 430062, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinfa","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Biology and Genetic Improvement of Oil Crops, Oil Crops Research Institute of Chinese Academy of Agricultural Sciences, Ministry of Agriculture and Rural Affairs, Wuhan 430062, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanzhong","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Biology and Genetic Improvement of Oil Crops, Oil Crops Research Institute of Chinese Academy of Agricultural Sciences, Ministry of Agriculture and Rural Affairs, Wuhan 430062, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Kieliszek, M. 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