{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T15:41:24Z","timestamp":1788104484938,"version":"build-2803163510"},"reference-count":45,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T00:00:00Z","timestamp":1698192000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>It is well documented that lean tissue mass (LTM) decreases with aging in patients with obesity, but there is no information available regarding muscle strength changes, a parameter that may be better associated with sarcopenic obesity (SO). The objectives of this study were to analyze the changes in LTM and fat mass (FM), muscle strength and muscle function with aging in women with obesity and to determine the prevalence of SO. LTM and FM were determined by DXA, muscle strength with the hand-grip test and muscle function with the 6 min walk test (6MWT) in 383 women with obesity. A redistribution of the LTM and FM occurred with age, characterized by a gain at the trunk to the detriment of the lower limbs, thus reducting in appendicular LTM indices. The physical performances evaluated by the muscle strength and muscle function decreased concomitantly, and the prevalence of low values for both these parameters was 22.8% and 13.4%, respectively, in the older patients. In summary, although a reduction in appendicular LTM and muscle performances occurred with age and resulted in an increase in the prevalence of SO, the number of women with obesity affected by SO remained low (n \u2264 15), even in those older than 60 years.<\/jats:p>","DOI":"10.3390\/nu15214517","type":"journal-article","created":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T06:19:58Z","timestamp":1698214798000},"page":"4517","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Relationship between Lean Tissue Mass and Muscle Function in Women with Obesity"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1727-1048","authenticated-orcid":false,"given":"Laurent","family":"Ma\u00efmoun","sequence":"first","affiliation":[{"name":"Depatment of Nuclear Medicine, CHU Montpellier, 34295 Montpellier, France"},{"name":"Physiology and Experimental Medicine of the Heart and Muscles (PhyMedExp), University of Montpellier, 34295 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4047-7440","authenticated-orcid":false,"given":"Elise","family":"Bourgeois","sequence":"additional","affiliation":[{"name":"Physiology and Experimental Medicine of the Heart and Muscles (PhyMedExp), University of Montpellier, 34295 Montpellier, France"},{"name":"Department of Endocrinology, Nutrition and Diabetes, Team Nutrition, Diabetes, CHU Montpellier, 34295 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Serrand","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Epidemiology, Public Health and Innovation in Methodology, CHU N\u00eemes, 30029 N\u00eemes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6420-1336","authenticated-orcid":false,"given":"Thibault","family":"Mura","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Epidemiology, Public Health and Innovation in Methodology, CHU N\u00eemes, 30029 N\u00eemes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8563-7278","authenticated-orcid":false,"given":"Jean-Paul","family":"Cristol","sequence":"additional","affiliation":[{"name":"Physiology and Experimental Medicine of the Heart and Muscles (PhyMedExp), University of Montpellier, 34295 Montpellier, France"},{"name":"Departement of Biochimy, Chu Montpellier, 34295 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justine","family":"Myzia","sequence":"additional","affiliation":[{"name":"Department of Clinical Physiology, CHU Montpellier, 34295 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Avignon","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Nutrition and Diabetes, Team Nutrition, Diabetes, CHU Montpellier, 34295 Montpellier, France"},{"name":"Desbrest Institute of Epidemiology and Public Health, IDESP UMR UA11 INSERM, University of Montpellier, 34295 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7044-2961","authenticated-orcid":false,"given":"Denis","family":"Mariano-Goulart","sequence":"additional","affiliation":[{"name":"Depatment of Nuclear Medicine, CHU Montpellier, 34295 Montpellier, France"},{"name":"Physiology and Experimental Medicine of the Heart and Muscles (PhyMedExp), University of Montpellier, 34295 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariane","family":"Sultan","sequence":"additional","affiliation":[{"name":"Physiology and Experimental Medicine of the Heart and Muscles (PhyMedExp), University of Montpellier, 34295 Montpellier, France"},{"name":"Department of Endocrinology, Nutrition and Diabetes, Team Nutrition, Diabetes, CHU Montpellier, 34295 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,10,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"M307","DOI":"10.1093\/gerona\/50A.6.M307","article-title":"Cross-sectional age differences in body composition in persons 60+ years of age","volume":"50","author":"Baumgartner","year":"1995","journal-title":"J. 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