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through Science and Education\u201d of Wuxi Health and Family Planning Commission","award":["32021005"],"award-info":[{"award-number":["32021005"]}]},{"name":"Key Talents Project of \u201cStrengthening Health through Science and Education\u201d of Wuxi Health and Family Planning Commission","award":["BK20200084"],"award-info":[{"award-number":["BK20200084"]}]},{"name":"Key Talents Project of \u201cStrengthening Health through Science and Education\u201d of Wuxi Health and Family Planning Commission","award":["ZDRC039"],"award-info":[{"award-number":["ZDRC039"]}]},{"name":"Key Talents Project of \u201cStrengthening Health through Science and Education\u201d of Wuxi Health and Family Planning Commission","award":["LGY2018016"],"award-info":[{"award-number":["LGY2018016"]}]},{"name":"Top Talents Project of the \u201cSix-one Project\u201d for High-level Health Talents in Jiangsu Province","award":["32122067"],"award-info":[{"award-number":["32122067"]}]},{"name":"Top Talents Project of the \u201cSix-one Project\u201d for High-level Health Talents in Jiangsu Province","award":["32021005"],"award-info":[{"award-number":["32021005"]}]},{"name":"Top Talents Project of the \u201cSix-one Project\u201d for High-level Health Talents in Jiangsu Province","award":["BK20200084"],"award-info":[{"award-number":["BK20200084"]}]},{"name":"Top Talents Project of the \u201cSix-one Project\u201d for High-level Health Talents in Jiangsu Province","award":["ZDRC039"],"award-info":[{"award-number":["ZDRC039"]}]},{"name":"Top Talents Project of the \u201cSix-one Project\u201d for High-level Health Talents in Jiangsu Province","award":["LGY2018016"],"award-info":[{"award-number":["LGY2018016"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: gastritis is a common stomach disease with a high global incidence and can potentially develop into gastric cancer. The treatment of gastritis focuses on medication or diets based on national guidelines. However, the specific diet that can alleviate gastritis remains largely unknown. Methods: we propose a microbiota-directed dietary strategy that investigates potential food factors using microbial exogenous metabolites. Given the current lack of understanding of the repeatable characteristics of gastric microbiota, we conducted a meta-analysis to identify the features of gastric bacteria. Local samples were collected as validation cohorts. Furthermore, RevEcoR was employed to identify bacteria\u2019s exogenous metabolites, and FooDB was used to retrieve foods that can target specific bacteria. Results: Bacteroides, Weissella, Actinomyces, Atopobium, Oribacterium, Peptostreptococcus, and Rothia were biomarkers between superficial gastritis (SG) and atrophic gastritis (AG) (AG_N) without H. pylori infection, whereas Bacillus, Actinomyces, Cutibacterium, Helicobacter, Novosphingobium, Pseudomonas, and Streptococcus were signatures between SG and AG (AG_P) with H. pylori infection. According to the exogenous metabolites, adenosyloobalamin, soybean, common wheat, dates, and barley were regarded as potential candidates for AG_N treatment, while gallate was regarded as a candidate for AG_P treatment. Conclusions: this study firstly profiled the gastric microbiota of AG and SG with or without H. pylori and provided a recommended diet for global AG according to exogenous metabolites.<\/jats:p>","DOI":"10.3390\/nu15224738","type":"journal-article","created":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T10:19:27Z","timestamp":1699525167000},"page":"4738","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Predicting Personalized Diets Based on Microbial Characteristics between Patients with Superficial Gastritis and Atrophic Gastritis"],"prefix":"10.3390","volume":"15","author":[{"given":"Xiaoxiang","family":"Gao","sequence":"first","affiliation":[{"name":"State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China"},{"name":"School of Food Science and Technology, Jiangnan University, Wuxi 214122, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pingping","family":"Yin","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China"},{"name":"School of Food Science and Technology, Jiangnan University, Wuxi 214122, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6339-8579","authenticated-orcid":false,"given":"Yilin","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Affiliated Hospital of Jiangnan University, Wuxi 214122, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3191-3123","authenticated-orcid":false,"given":"Leilei","family":"Yu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China"},{"name":"School of Food Science and Technology, Jiangnan University, Wuxi 214122, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengwei","family":"Tian","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China"},{"name":"School of Food Science and Technology, Jiangnan University, Wuxi 214122, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianxin","family":"Zhao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China"},{"name":"School of Food Science and Technology, Jiangnan University, Wuxi 214122, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China"},{"name":"School of Food Science and Technology, Jiangnan University, Wuxi 214122, China"},{"name":"National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuzheng","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Affiliated Hospital of Jiangnan University, Wuxi 214122, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qixiao","family":"Zhai","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China"},{"name":"School of Food Science and Technology, Jiangnan University, Wuxi 214122, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Liu, D., Chen, S., Gou, Y., Yu, W., Zhou, H., Zhang, R., Wang, J., Ye, F., Liu, Y., and Sun, B. 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