{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T21:32:12Z","timestamp":1787952732681,"version":"build-2784847793"},"reference-count":75,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T00:00:00Z","timestamp":1700265600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico","award":["1221098"],"award-info":[{"award-number":["1221098"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Nonalcoholic fatty liver disease (NAFLD) is pediatrics\u2019 most common chronic liver disease. The incidence is high in children and adolescents with obesity, which is associated with an increased risk of disease progression. Currently, there is no effective drug therapy in pediatrics; therefore, lifestyle interventions remain the first line of treatment. This review aims to present an updated compilation of the scientific evidence for treating this pathology, including lifestyle modifications, such as exercise and dietary changes, highlighting specific nutritional strategies. The bibliographic review was carried out in different databases, including studies within the pediatric population where dietary and\/or nutritional interventions were used to treat NAFLD. Main interventions include diets low in carbohydrates, free sugars, fructose, and lipids, in addition to healthy eating patterns and possible nutritional interventions with n-3 polyunsaturated fatty acids (EPA and DHA), amino acids (cysteine, L-carnitine), cysteamine, vitamins, and probiotics (one strain or multi-strain). Lifestyle changes remain the main recommendation for children with NAFLD. Nevertheless, more studies are required to elucidate the effectiveness of specific nutrients and bioactive compounds in this population.<\/jats:p>","DOI":"10.3390\/nu15224829","type":"journal-article","created":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T07:33:18Z","timestamp":1700292798000},"page":"4829","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Dietary and Nutritional Interventions in Nonalcoholic Fatty Liver Disease in Pediatrics"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4899-9709","authenticated-orcid":false,"given":"Camila","family":"Far\u00edas","sequence":"first","affiliation":[{"name":"Department of Nutrition, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila","family":"Cisternas","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0400-2164","authenticated-orcid":false,"given":"Juan Cristobal","family":"Gana","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology and Nutrition, Division of Pediatrics, School of Medicine, Pontificia Universidad Cat\u00f3lica de Chile, Santiago 8330023, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8540-1326","authenticated-orcid":false,"given":"Gigliola","family":"Alberti","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology and Nutrition, Division of Pediatrics, School of Medicine, Pontificia Universidad Cat\u00f3lica de Chile, Santiago 8330023, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9661-0377","authenticated-orcid":false,"given":"Francisca","family":"Echeverr\u00eda","sequence":"additional","affiliation":[{"name":"Nutrition and Dietetic School, Department of Health Sciences, Pontificia Universidad Cat\u00f3lica de Chile, Santiago 8331150, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1788-6667","authenticated-orcid":false,"given":"Luis A.","family":"Videla","sequence":"additional","affiliation":[{"name":"Molecular and Clinical Pharmacology Program, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago 8380000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9813-8815","authenticated-orcid":false,"given":"Lorena","family":"Mercado","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasna","family":"Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile"},{"name":"Escuela de Nutrici\u00f3n y Diet\u00e9tica, Facultad de Farmacia, Universidad de Valpara\u00edso, Valpara\u00edso 2360134, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9298-6142","authenticated-orcid":false,"given":"Rodrigo","family":"Valenzuela","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology and Nutrition, Division of Pediatrics, School of Medicine, Pontificia Universidad Cat\u00f3lica de Chile, Santiago 8330023, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.47162\/RJME.61.4.04","article-title":"Pediatric nonalcoholic fatty liver disease\u2014A changing diagnostic paradigm","volume":"61","author":"Trandafir","year":"2020","journal-title":"Rom. 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