{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T04:14:29Z","timestamp":1791778469497,"version":"4.3.4"},"reference-count":94,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,1,22]],"date-time":"2024-01-22T00:00:00Z","timestamp":1705881600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University of Isfahan, Isfahan, Iran"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: The effects of combining resistance training (RT) and concurrent training (CT; resistance + endurance training) with varied protein doses on bone measures remain poorly understood. Hence, we conducted a comparison of the impacts of two high-protein diets (1.6 or 3.2 g kg\u22121 d\u22121) over 16 weeks in resistance-trained males, either with CT or RT alone. Methods: A total of forty-eight males, all of whom were resistance-trained, had the following demographics: 26.6 \u00b1 6 years, body mass index: 25.6 \u00b1 2.9 kg m\u22122 administered either 3.2 g kg\u22121 d\u22121 protein (CT2; n = 12; RT2; n = 12) or 1.6 g kg\u22121 d\u22121 protein (CT1; n = 12; RT1; n = 12) during 16 weeks (four sessions\u00b7w\u22121). Bone parameters were assessed pre- and post-intervention. Results: There was no significant interaction between the intervention group and time for the legs, arms, ribs, or pelvis area BMC and BMD (p &gt; 0.05). For the BMD of the pelvis and the BMC of the right ribs, however, there were significant time effects noted (p &lt; 0.05). Furthermore, there was a significant interaction between the intervention group and time in the lumbar and thoracic spines, with a particular time effect noted for the thoracic spine region (p &lt; 0.05). The regional differences in skeletal responses to the intervention are highlighted by these data. Conclusion: Our findings show that the intake of two high-protein diets combined with RT and CT during 16 weeks had no adverse effects on bone tissue parameters. While these findings indicate that protein intake between 2 and 3 times the current RDI does not promote bone demineralization when consumed in conjunction with exercise, future studies investigating the long-term effects of chronic high protein intake on bone tissue health are warranted.<\/jats:p>","DOI":"10.3390\/nu16020325","type":"journal-article","created":{"date-parts":[[2024,1,22]],"date-time":"2024-01-22T06:49:31Z","timestamp":1705906171000},"page":"325","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["High-Protein Diets during either Resistance or Concurrent Training Have No Detrimental Effect on Bone Parameters in Resistance-Trained Males"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1433-2906","authenticated-orcid":false,"given":"Reza","family":"Bagheri","sequence":"first","affiliation":[{"name":"Department of Exercise Physiology, Faculty of Sport Sciences, University of Isfahan, Isfahan 8174673441, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zohreh","family":"Karimi","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sport Sciences, Science and Research Branch, Islamic Azad University, Tehran 1477893855, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7510-5403","authenticated-orcid":false,"given":"Zeynabalsadat","family":"Mousavi","sequence":"additional","affiliation":[{"name":"Nutrition and Food Service, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran 1416634793, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahdi","family":"Ziaee Bashirzad","sequence":"additional","affiliation":[{"name":"Department of Sport Science, Islamic Azad University, Bojnourd Branch, Bojnourd 9417697796, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donny M.","family":"Camera","sequence":"additional","affiliation":[{"name":"Department of Health and Biostatistics, Swinburne University, Melbourne, VIC 3122, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramin","family":"Sadeghi","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad 9177949025, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vahid Reza","family":"Dabbagh","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad 9177949025, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Kargarfard","sequence":"additional","affiliation":[{"name":"Department of Exercise Physiology, Faculty of Sport Sciences, University of Isfahan, Isfahan 8174673441, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1468-6029","authenticated-orcid":false,"given":"Frederic","family":"Dutheil","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Clermont Auvergne, CNRS, LaPSCo, Physiological and Psychosocial Stress, CHU Clermont-Ferrand, University Hospital of Clermont-Ferrand, Preventive and Occupational Medicine, Witty Fit, F-63000 Clermont-Ferrand, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Pourabbas, M., Bagheri, R., Hooshmand Moghadam, B., Willoughby, D.S., Candow, D.G., Elliott, B.T., Forbes, S.C., Ashtary-Larky, D., Eskandari, M., and Wong, A. 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