{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T16:14:28Z","timestamp":1790957668606,"version":"4.1.0"},"reference-count":143,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T00:00:00Z","timestamp":1708387200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Bio-Based Industries Joint Undertaking (JU)","award":["888003"],"award-info":[{"award-number":["888003"]}]},{"name":"Bio-Based Industries Joint Undertaking (JU)","award":["101084344"],"award-info":[{"award-number":["101084344"]}]},{"name":"Bio-Based Industries Joint Undertaking (JU)","award":["101112378"],"award-info":[{"award-number":["101112378"]}]},{"name":"HORIZON-CL6-2022-FARM2FORK-01 (2023\u20132026)","award":["888003"],"award-info":[{"award-number":["888003"]}]},{"name":"HORIZON-CL6-2022-FARM2FORK-01 (2023\u20132026)","award":["101084344"],"award-info":[{"award-number":["101084344"]}]},{"name":"HORIZON-CL6-2022-FARM2FORK-01 (2023\u20132026)","award":["101112378"],"award-info":[{"award-number":["101112378"]}]},{"name":"HORIZON-JU-CBE-2022-R-04 (2023\u20132026)","award":["888003"],"award-info":[{"award-number":["888003"]}]},{"name":"HORIZON-JU-CBE-2022-R-04 (2023\u20132026)","award":["101084344"],"award-info":[{"award-number":["101084344"]}]},{"name":"HORIZON-JU-CBE-2022-R-04 (2023\u20132026)","award":["101112378"],"award-info":[{"award-number":["101112378"]}]},{"name":"HORIZON-CL6-2023-GOVERNANCE-01-17 (2023\u20132026)","award":["888003"],"award-info":[{"award-number":["888003"]}]},{"name":"HORIZON-CL6-2023-GOVERNANCE-01-17 (2023\u20132026)","award":["101084344"],"award-info":[{"award-number":["101084344"]}]},{"name":"HORIZON-CL6-2023-GOVERNANCE-01-17 (2023\u20132026)","award":["101112378"],"award-info":[{"award-number":["101112378"]}]},{"name":"MICINN","award":["888003"],"award-info":[{"award-number":["888003"]}]},{"name":"MICINN","award":["101084344"],"award-info":[{"award-number":["101084344"]}]},{"name":"MICINN","award":["101112378"],"award-info":[{"award-number":["101112378"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Vitamin D deficiency is currently a significant public health issue closely linked to numerous diseases, such as breast cancer. This study aims to determine the estimated optimal serum levels of vitamin D to have a protective effect against breast cancer, in addition to exploring the biological mechanisms and risk factors involved. A literature search of articles published in the last 5 years was conducted, and simple statistical analyses using mean and standard deviation were performed to calculate the average concentration of vitamin D from different available studies. It has been observed that serum levels of vitamin D \u2265 40.26 ng\/mL \u00b1 14.19 ng\/mL could exert a protective effect against breast cancer. Additionally, various biological mechanisms, such as those related to the immune system, and risk factors like diet implicated in this relationship were elucidated. Consequently, it can be concluded that proper serum levels of vitamin D may have a protective effect against breast cancer, and dietary supplementation may be an appropriate procedure to achieve these optimal vitamin D concentrations.<\/jats:p>","DOI":"10.3390\/nu16050573","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T05:10:04Z","timestamp":1708405804000},"page":"573","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["The Impact of Vitamin D and Its Dietary Supplementation in Breast Cancer Prevention: An Integrative Review"],"prefix":"10.3390","volume":"16","author":[{"given":"Ant\u00eda","family":"Torres","sequence":"first","affiliation":[{"name":"Nutrition and Bromatology Group, Department of Analytical Chemistry and Food Science, Faculty of Science, University de Vigo, E-32004 Ourense, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Cameselle","sequence":"additional","affiliation":[{"name":"Nutrition and Bromatology Group, Department of Analytical Chemistry and Food Science, Faculty of Science, University de Vigo, E-32004 Ourense, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5164-3004","authenticated-orcid":false,"given":"Paz","family":"Otero","sequence":"additional","affiliation":[{"name":"Nutrition and Bromatology Group, Department of Analytical Chemistry and Food Science, Faculty of Science, University de Vigo, E-32004 Ourense, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9215-9737","authenticated-orcid":false,"given":"Jesus","family":"Simal-Gandara","sequence":"additional","affiliation":[{"name":"Nutrition and Bromatology Group, Department of Analytical Chemistry and Food Science, Faculty of Science, University de Vigo, E-32004 Ourense, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,20]]},"reference":[{"key":"ref_1","unstructured":"Institute of Medicine (US) Committee to Review Dietary Reference Intakes for Vitamin D and Calcium, Ross, A.C., Taylor, C.L., Yaktine, A.L., and Valle, H.B. 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