{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:00:02Z","timestamp":1787029202481,"version":"build-2736575974"},"reference-count":36,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2024,2,22]],"date-time":"2024-02-22T00:00:00Z","timestamp":1708560000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>This study aimed to describe the latest 25-hydroxyvitamin D (25(OH)D) status of the South Korean population aged \u2265 20 years using 25(OH)D concentrations measured by liquid chromatography\u2013tandem mass spectrometry and to determine the factors associated with total 25(OH)D concentrations. This cross-sectional, retrospective study consecutively selected 119,335 subjects with a median age of 57 (20\u2013101) years who underwent health checkups among 13 Korean cities during 2017\u20132022. The total 25(OH)D concentration was 54.5 \u00b1 24.0 nmol\/L (mean \u00b1 SD). The 7.6%, 47.5%, and 82.9% of participants had 25(OH)D less than 25, 50, and 75 nmol\/L, respectively. The prevalence of 25(OH)D deficiency (&lt;25 nmol\/L) was higher in females than in males (8.9% vs. 6.1%) and varied between age groups, decreasing in older subjects. Those aged 20\u201329 years had the highest prevalence of 25(OH)D deficiency (23.0% in females and 20.1% in males), which also varied between cities. In the adjusted model, female sex, older age, summer and autumn seasons, lower body mass index (&lt;25 kg\/m2), and lower high-sensitivity C-reactive protein concentration (&lt;1 mg\/L) were associated with higher total 25(OH)D concentrations. This study could provide an exact understanding of the status of vitamin D and help devise strategies to prevent vitamin D deficiency among the Korean population.<\/jats:p>","DOI":"10.3390\/nu16050604","type":"journal-article","created":{"date-parts":[[2024,2,22]],"date-time":"2024-02-22T11:28:47Z","timestamp":1708601327000},"page":"604","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Vitamin D Status and Reference Intervals Measured by Liquid Chromatography\u2013Tandem Mass Spectrometry for the Early Adulthood to Geriatric Ages in a South Korean Population during 2017\u20132022"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6842-0234","authenticated-orcid":false,"given":"Jooheon","family":"Park","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine, Chonnam National University Hwasun Hospital, Hwasun 58128, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongjun","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Chonnam National University Hwasun Hospital, Hwasun 58128, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seon","family":"Cho","sequence":"additional","affiliation":[{"name":"Health Promotion Research Institute, Korea Association of Health Promotion, Seoul 07572, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyeran","family":"Park","sequence":"additional","affiliation":[{"name":"Health Promotion Research Institute, Korea Association of Health Promotion, Seoul 07572, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suyoung","family":"Kim","sequence":"additional","affiliation":[{"name":"Health Promotion Research Institute, Korea Association of Health Promotion, Seoul 07572, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han-Ik","family":"Cho","sequence":"additional","affiliation":[{"name":"MEDIcheck LAB, Korea Association of Health Promotion, Seoul 07572, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0637-4364","authenticated-orcid":false,"given":"Eun-Hee","family":"Nah","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Chonnam National University Hwasun Hospital, Hwasun 58128, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1056\/NEJMra070553","article-title":"Vitamin D Deficiency","volume":"357","author":"Holick","year":"2007","journal-title":"N. 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