{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T06:52:40Z","timestamp":1768719160611,"version":"3.49.0"},"reference-count":41,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T00:00:00Z","timestamp":1709164800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Research Center of Prevention and Treatment of Senescence Syndrome, School of Medicine Zhejiang University","award":["2022010002"],"award-info":[{"award-number":["2022010002"]}]},{"name":"Research Center of Prevention and Treatment of Senescence Syndrome, School of Medicine Zhejiang University","award":["2023C03163"],"award-info":[{"award-number":["2023C03163"]}]},{"name":"Research Center of Prevention and Treatment of Senescence Syndrome, School of Medicine Zhejiang University","award":["2020E10004"],"award-info":[{"award-number":["2020E10004"]}]},{"name":"\u201cPioneer\u201d and \u201cLeading Goose\u201d R&amp;D Programs of Zhejiang Province","award":["2022010002"],"award-info":[{"award-number":["2022010002"]}]},{"name":"\u201cPioneer\u201d and \u201cLeading Goose\u201d R&amp;D Programs of Zhejiang Province","award":["2023C03163"],"award-info":[{"award-number":["2023C03163"]}]},{"name":"\u201cPioneer\u201d and \u201cLeading Goose\u201d R&amp;D Programs of Zhejiang Province","award":["2020E10004"],"award-info":[{"award-number":["2020E10004"]}]},{"name":"Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province","award":["2022010002"],"award-info":[{"award-number":["2022010002"]}]},{"name":"Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province","award":["2023C03163"],"award-info":[{"award-number":["2023C03163"]}]},{"name":"Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province","award":["2020E10004"],"award-info":[{"award-number":["2020E10004"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: The aim of the current study was to explore the trajectories, variabilities, and cumulative exposures of body mass index (BMI) and waist circumference (WC) with cardiac arrhythmia (CA) risks. Methods: In total, 35,739 adults from the Kailuan study were included. BMI and WC were measured repeatedly during the 2006\u20132010 waves. CA was identified via electrocardiogram diagnosis. BMI and WC trajectories were fitted using a group-based trajectory model. The associations were estimated using Cox proportional hazards models. Results: We identified four stable trajectories for BMI and WC, respectively. Neither the BMI trajectories nor the baseline BMI values were associated with the risk of CA. Compared to the low-stable WC group, participants in the high-stable WC group had a higher risk of CA (hazard ratio (HR) = 1.40, 95% confidence interval (CI): 1.06, 1.86). Interestingly, the cumulative exposures of BMI and WC instead of their variabilities were associated with the risk of CA. In the stratified analyses, the positive associations of the high-stable WC group with the risk of CA were found in females only (HR = 1.98, 95% CI: 1.02, 3.83). Conclusions: A high-stable WC trajectory is associated with a higher risk of CA among Chinese female adults, underscoring the potential of WC rather than BMI to identify adults who are at risk.<\/jats:p>","DOI":"10.3390\/nu16050704","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T08:13:44Z","timestamp":1709194424000},"page":"704","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Trajectories of Body Mass Index and Waist Circumference in Relation to the Risk of Cardiac Arrhythmia: A Prospective Cohort Study"],"prefix":"10.3390","volume":"16","author":[{"given":"Liming","family":"Zhang","sequence":"first","affiliation":[{"name":"Second Affiliated Hospital, and School of Public Health, The Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou 310058, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuohua","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kailuan General Hospital, Hebei United University, Tangshan 063000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingqi","family":"Cao","sequence":"additional","affiliation":[{"name":"Second Affiliated Hospital, and School of Public Health, The Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou 310058, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiening","family":"Yu","sequence":"additional","affiliation":[{"name":"Second Affiliated Hospital, and School of Public Health, The Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou 310058, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0774-7399","authenticated-orcid":false,"given":"Zhenqing","family":"Yang","sequence":"additional","affiliation":[{"name":"Second Affiliated Hospital, and School of Public Health, The Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou 310058, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeinab","family":"Abdelrahman","sequence":"additional","affiliation":[{"name":"Centre for Public Health, Queen\u2019s University of Belfast, Belfast BT12 6BA, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gan","family":"Yang","sequence":"additional","affiliation":[{"name":"Second Affiliated Hospital, and School of Public Health, The Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou 310058, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Public Health, Robbins College of Human Health and Sciences, Baylor University, Waco, TX 76711, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuehong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Harvard T.H. Chan School of Public Health; Channing Division of Network Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA 02115, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8409-7636","authenticated-orcid":false,"given":"Yimin","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Zhejiang University, Hangzhou 310058, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shouling","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kailuan General Hospital, Hebei United University, Tangshan 063000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zuyun","family":"Liu","sequence":"additional","affiliation":[{"name":"Second Affiliated Hospital, and School of Public Health, The Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou 310058, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e254","DOI":"10.1161\/CIR.0000000000000950","article-title":"Heart Disease and Stroke Statistics-2021 Update: A Report From the American Heart Association","volume":"143","author":"Virani","year":"2021","journal-title":"Circulation"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1161\/CIRCULATIONAHA.113.005119","article-title":"Worldwide epidemiology of atrial fibrillation: A Global Burden of Disease 2010 Study","volume":"129","author":"Chugh","year":"2014","journal-title":"Circulation"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1093\/eurheartj\/eht280","article-title":"Projections on the number of individuals with atrial fibrillation in the European Union, from 2000 to 2060","volume":"34","author":"Krijthe","year":"2013","journal-title":"Eur. 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