{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:53:39Z","timestamp":1760144019892,"version":"build-2065373602"},"reference-count":27,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T00:00:00Z","timestamp":1710460800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Patients undergoing gastrectomy for gastric cancer may experience alterations in olfaction, yet the association between olfactory changes and postoperative weight loss remains uncertain. This study aimed to elucidate the relationship between olfactory changes and postoperative weight loss in patients with gastric cancer. Patients who underwent radical gastrectomy for gastric cancer between February 2022 and August 2022 were included in the study. Those experiencing a higher Visual Analog Scale (VAS) score postoperatively compared to preoperatively were deemed to have undergone olfactory changes. Postoperative weight loss was determined using the 75th percentile as a cutoff value, designating patients surpassing this threshold as experiencing significant weight loss. Multivariate logistic regression analysis was employed to identify risk factors for postoperative weight loss, with statistical significance set at p &lt; 0.05. Out of 58 patients, 10 (17.2%) exhibited olfactory changes. The rate of postoperative weight loss at one month was markedly higher in the group with olfactory changes compared to those without (9.6% versus 6.2%, respectively; p = 0.002). In addition, the group experiencing olfactory changes demonstrated significantly lower energy intake compared to the group without such changes (1050 kcal versus 1250 kcal, respectively; p = 0.029). Logistic regression analysis revealed olfactory changes as an independent risk factor for significant weight loss at one month postoperatively (odds ratio: 7.64, 95% confidence interval: 1.09\u201371.85, p = 0.048). In conclusion, olfactory changes emerged as an independent risk factor for postoperative weight loss at one month in patients with gastric cancer following gastrectomy.<\/jats:p>","DOI":"10.3390\/nu16060851","type":"journal-article","created":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T14:05:25Z","timestamp":1710511525000},"page":"851","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Impact of Olfactory Change on Postoperative Body Weight Loss in Patients with Gastric Cancer after Gastrectomy"],"prefix":"10.3390","volume":"16","author":[{"given":"Hiromi","family":"Matsuo","sequence":"first","affiliation":[{"name":"Department of Nutrition and Metabolism, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, Japan"},{"name":"Department of Nutrition Management, Cancer Institute Hospital of JFCR, 3-8-31 Ariake, Koto-ku, Tokyo 135-0063, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0541-2357","authenticated-orcid":false,"given":"Ryota","family":"Matsui","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Cancer Institute Hospital of JFCR, 3-8-31 Ariake, Koto-ku, Tokyo 135-0063, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koshi","family":"Kumagai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Cancer Institute Hospital of JFCR, 3-8-31 Ariake, Koto-ku, Tokyo 135-0063, Japan"},{"name":"Department of Upper Gastrointestinal Surgery, Kitasato University Hospital, 1-15-1 Kitasato, Minami-ku, Sagamihara-shi 252-0375, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Ida","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Cancer Institute Hospital of JFCR, 3-8-31 Ariake, Koto-ku, Tokyo 135-0063, Japan"},{"name":"Department of Gastroenterological Surgery, Kumamoto University Hospital, 1-1-1 Honjo, Chuo-ku, Kumamoto-shi 860-8556, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1888-0953","authenticated-orcid":false,"given":"Yoko","family":"Saino","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Metabolism, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, Japan"},{"name":"Department of Nutrition Management, Cancer Institute Hospital of JFCR, 3-8-31 Ariake, Koto-ku, Tokyo 135-0063, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aya","family":"Fujihara","sequence":"additional","affiliation":[{"name":"Department of Nutrition Management, Cancer Institute Hospital of JFCR, 3-8-31 Ariake, Koto-ku, Tokyo 135-0063, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kumi","family":"Takagi","sequence":"additional","affiliation":[{"name":"Department of Nutrition Management, Cancer Institute Hospital of JFCR, 3-8-31 Ariake, Koto-ku, Tokyo 135-0063, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukiko","family":"Itami","sequence":"additional","affiliation":[{"name":"Department of Nutrition Management, Cancer Institute Hospital of JFCR, 3-8-31 Ariake, Koto-ku, Tokyo 135-0063, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Misuzu","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Nutrition Management, Cancer Institute Hospital of JFCR, 3-8-31 Ariake, Koto-ku, Tokyo 135-0063, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Moriya","sequence":"additional","affiliation":[{"name":"Department of Nutrition Management, Cancer Institute Hospital of JFCR, 3-8-31 Ariake, Koto-ku, Tokyo 135-0063, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuna","family":"Izumi-Mishima","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Metabolism, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiro","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Metabolism, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1997-082X","authenticated-orcid":false,"given":"Yasuo M.","family":"Tsutsumi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care, Hiroshima University, 1-2-3 Kasumi, Hiroshima 734-8551, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Souya","family":"Nunobe","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Cancer Institute Hospital of JFCR, 3-8-31 Ariake, Koto-ku, Tokyo 135-0063, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rie","family":"Tsutsumi","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Metabolism, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, Japan"},{"name":"Department of Anesthesiology and Critical Care, Hiroshima University, 1-2-3 Kasumi, Hiroshima 734-8551, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2468-2363","authenticated-orcid":false,"given":"Hiroshi","family":"Sakaue","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Metabolism, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.5230\/jgc.2022.22.e15","article-title":"Larger Remaining Stomach Volume Is Associated with Better Nutrition and Muscle Preservation in Patients with Gastric Cancer Receiving Distal Gastrectomy with Gastroduodenostomy","volume":"22","author":"Kim","year":"2022","journal-title":"J. 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