{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T12:13:21Z","timestamp":1781612001370,"version":"3.54.5"},"reference-count":93,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T00:00:00Z","timestamp":1710806400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003566","name":"Ministry of Oceans and Fisheries, Republic of Korea","doi-asserted-by":"publisher","award":["20220027"],"award-info":[{"award-number":["20220027"]}],"id":[{"id":"10.13039\/501100003566","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Dietary fiber intake and physical fitness are independently associated with high-sensitivity C-reactive protein (hs-CRP) levels. Nevertheless, the association between dietary fiber intake, measures of physical fitness, and hs-CRP levels has not yet been fully evaluated. We investigated the influence of a combination of dietary fiber intake and measures of physical fitness, including hand grip strength, resistance training, and metabolic equivalents of tasks, on hs-CRP levels. Data collected from the Korea National Health and Nutrition Examination Survey (KNHANES) spanning 2015 to 2018 were used in this study. A total of 16,934 participants (7434 men and 9500 women aged \u226519 years) were included in this study. After adjusting for confounding factors (age, education, income, marital status, smoking status, drinking habits, total energy intake, and aerobic physical activity), we employed a multivariable logistic model to examine the association of dietary fiber intake and measures of physical fitness with hs-CRP levels. Among women, the odds of high hs-CRP levels were lower in those with the highest dietary fiber intake and superior grip strength compared to in women with the lowest dietary fiber intake and weaker grip strength (odds ratio [OR] = 0.40, 95% confidence interval [CI] = 0.24\u20130.68). The highest dietary fiber intake who participated in resistance exercise at least three times per week had a reduced odds of high hs-CRP levels compared with those with the lowest dietary fiber intake who did not engage in resistance exercise in both men and women (OR = 0.53, 95% CI = 0.32\u20130.89; OR = 0.40, 95% CI = 0.19\u20130.84, respectively). Our findings indicate that dietary fiber intake and high levels of physical fitness were associated with reduced odds of elevated hs-CRP levels.<\/jats:p>","DOI":"10.3390\/nu16060888","type":"journal-article","created":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T09:39:31Z","timestamp":1710841171000},"page":"888","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Association of Dietary Fiber and Measures of Physical Fitness with High-Sensitivity C-Reactive Protein"],"prefix":"10.3390","volume":"16","author":[{"given":"Ming-Zhen","family":"Su","sequence":"first","affiliation":[{"name":"Department of Food and Nutrition, Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1471-2204","authenticated-orcid":false,"given":"Suyeon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition, Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0828-184X","authenticated-orcid":false,"given":"Dayeon","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition, Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"17K","DOI":"10.1016\/S0002-9149(03)00774-4","article-title":"High-sensitivity C-reactive protein and cardiovascular risk: Rationale for screening and primary prevention","volume":"92","author":"Ridker","year":"2003","journal-title":"Am. J. Cardiol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1161\/01.CIR.0000053730.47739.3C","article-title":"Clinical application of C-reactive protein for cardiovascular disease detection and prevention","volume":"107","author":"Ridker","year":"2003","journal-title":"Circulation"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"159","DOI":"10.3389\/fpubh.2016.00159","article-title":"Use your words carefully: What is a chronic disease?","volume":"4","author":"Bernell","year":"2016","journal-title":"Front. Public Health"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1002\/jcla.21920","article-title":"Association of serum hs-CRP levels with the presence of obesity, diabetes mellitus, and other cardiovascular risk factors","volume":"30","author":"Ebrahimi","year":"2016","journal-title":"J. Clin. Lab. Anal."},{"key":"ref_5","first-page":"121","article-title":"Influence of inflammation and adipocyte biochemical markers on the components of metabolic syndrome","volume":"20","author":"Vesa","year":"2020","journal-title":"Exp. Ther. Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"3A","DOI":"10.1016\/j.amjcard.2005.11.010","article-title":"The metabolic syndrome: Inflammation, diabetes mellitus, and cardiovascular disease","volume":"97","author":"Haffner","year":"2006","journal-title":"Am. J. Cardiol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1161\/01.CIR.102.1.42","article-title":"Chronic subclinical inflammation as part of the insulin resistance syndrome: The Insulin Resistance Atherosclerosis Study (IRAS)","volume":"102","author":"Festa","year":"2000","journal-title":"Circulation"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1161\/01.CIR.0000052939.59093.45","article-title":"Markers of inflammation and cardiovascular disease: Application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association","volume":"107","author":"Pearson","year":"2003","journal-title":"Circulation"},{"key":"ref_9","first-page":"115","article-title":"Metabolic syndrome and high-sensitivity C-reactive protein in Cubans","volume":"19","author":"Huffman","year":"2009","journal-title":"Ethn. Dis."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0377-8401(01)00193-6","article-title":"The nutritional significance of \u201cdietary fibre\u201d analysis","volume":"90","author":"Knudsen","year":"2001","journal-title":"Anim. Feed Sci. Tech."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1177\/0884533611416126","article-title":"Benefits of dietary fiber in clinical nutrition","volume":"26","author":"Klosterbuer","year":"2011","journal-title":"Nutr. Clin. Pract."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1093\/ajcn\/31.10.S21","article-title":"Nutritional implications of dietary fiber","volume":"31","author":"Cummings","year":"1978","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1080\/10408397509527201","article-title":"Dietary fiber in human nutrition","volume":"7","author":"Spiller","year":"1975","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2929","DOI":"10.1007\/s00467-022-05837-2","article-title":"The benefits of dietary fiber: The gastrointestinal tract and beyond","volume":"38","author":"Snauwaert","year":"2023","journal-title":"Pediatr. Nephrol."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Gustafson, C.R., and Rose, D.J. (2022). US Consumer Identification of the Health Benefits of Dietary Fiber and Consideration of Fiber When Making Food Choices. Nutrients, 14.","DOI":"10.3390\/nu14112341"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1038\/ejcn.2009.61","article-title":"The association of fruits, vegetables, antioxidant vitamins and fibre intake with high-sensitivity C-reactive protein: Sex and body mass index interactions","volume":"63","author":"Oliveira","year":"2009","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1093\/jn\/134.5.1181","article-title":"Dietary fiber and C-reactive protein: Findings from national health and nutrition examination survey data","volume":"134","author":"Ajani","year":"2004","journal-title":"J. Nutr."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1038\/s41430-021-00996-1","article-title":"The associations between whole grain and refined grain intakes and serum C-reactive protein","volume":"76","author":"Taskinen","year":"2022","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"971","DOI":"10.2147\/CIA.S356947","article-title":"Association Between C-Reactive Protein and Relative Handgrip Strength in Postmenopausal Korean Women Aged 45\u201380 Years: A Cross-Sectional Study","volume":"17","author":"Son","year":"2022","journal-title":"Clin. Interv. Aging"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1177\/2047487316680695","article-title":"Association of grip strength with cardiovascular risk markers","volume":"24","author":"Gubelmann","year":"2017","journal-title":"Eur. J. Prev. Cardiol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.18632\/aging.101529","article-title":"Inverse relationship between serum hsCRP concentration and hand grip strength in older adults: A nationwide population-based study","volume":"10","author":"Kim","year":"2018","journal-title":"Aging"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1038\/ejcn.2013.261","article-title":"Effect of inflammation on handgrip strength in the non-critically ill is independent from age, gender and body composition","volume":"68","author":"Norman","year":"2014","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.exger.2018.07.021","article-title":"Effect of resistance training on inflammatory markers of older adults: A meta-analysis","volume":"111","author":"Sardeli","year":"2018","journal-title":"Exp. Gerontol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/sms.12906","article-title":"Combined aerobic and resistance training decreases inflammation markers in healthy men","volume":"28","author":"Ihalainen","year":"2018","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1001\/archinte.162.11.1286","article-title":"Relationship between physical activity and inflammation among apparently healthy middle-aged and older US adults","volume":"162","author":"Abramson","year":"2002","journal-title":"Arch. Intern. Med."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1093\/aje\/153.3.242","article-title":"Association between physical activity and markers of inflammation in a healthy elderly population","volume":"153","author":"Geffken","year":"2001","journal-title":"Am. J. Epidemiol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"M709","DOI":"10.1093\/gerona\/55.12.M709","article-title":"Cross-sectional and prospective relationships of interleukin-6 and C-reactive protein with physical performance in elderly persons: MacArthur studies of successful aging","volume":"55","author":"Taaffe","year":"2000","journal-title":"J. Gerontol. Biol. Sci. Med. Sci."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1161\/01.CIR.0000016346.14762.71","article-title":"Physical activity and hemostatic and inflammatory variables in elderly men","volume":"105","author":"Wannamethee","year":"2002","journal-title":"Circulation"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1161\/01.ATV.0000087036.75849.0B","article-title":"Strikingly low circulating CRP concentrations in ultramarathon runners independent of markers of adiposity: How low can you go?","volume":"23","author":"Tomaszewski","year":"2003","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1161\/01.CIR.99.2.237","article-title":"C-Reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: Results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992","volume":"99","author":"Koenig","year":"1999","journal-title":"Circulation"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/S0002-9149(02)03175-2","article-title":"Association of leisure-time physical activity on inflammation markers (C-reactive protein, white cell blood count, serum amyloid A, and fibrinogen) in healthy subjects (from the ATTICA study)","volume":"91","author":"Pitsavos","year":"2003","journal-title":"Am. J. Cardiol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/S0002-9149(99)00491-9","article-title":"Survey of C-reactive protein and cardiovascular risk factors in apparently healthy men","volume":"84","author":"Rohde","year":"1999","journal-title":"Am. J. Cardiol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.amjcard.2003.09.046","article-title":"Effect of physical activity on serum C-reactive protein","volume":"93","author":"Albert","year":"2004","journal-title":"Am. J. Cardiol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1177\/0003319711423386","article-title":"Moderate intensities of leisure-time physical activity are associated with lower levels of high-sensitivity C-reactive protein in healthy middle-aged men","volume":"63","author":"Behre","year":"2012","journal-title":"Angiology"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.atherosclerosis.2005.06.015","article-title":"Associations of leisure time physical activity, self-rated physical fitness, and estimated aerobic fitness with serum C-reactive protein among 3803 adults","volume":"185","author":"Katja","year":"2006","journal-title":"Atherosclerosis"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/ije\/dyt228","article-title":"Data resource profile: The Korea national health and nutrition examination survey (KNHANES)","volume":"43","author":"Kweon","year":"2014","journal-title":"Int. J. Epidemiol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"e27641","DOI":"10.17795\/mejrh-27641","article-title":"Hand grip strength in pregnant and non-pregnant females","volume":"2","author":"Mbada","year":"2015","journal-title":"Middle East J. Rehabil. Health Stud."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.diabres.2006.04.013","article-title":"Appropriate waist circumference cutoff points for central obesity in Korean adults","volume":"75","author":"Lee","year":"2007","journal-title":"Diabetes Res. Clin. Pract."},{"key":"ref_39","first-page":"53","article-title":"Cut-off value of waist circumference for metabolic syndrome patients in Korean adult population","volume":"13","author":"Choi","year":"2004","journal-title":"J. Korean Soc. Study Obes."},{"key":"ref_40","unstructured":"World Health Organization (2000). The Asia-Pacific Perspective: Redefining Obesity and Its Treatment, World Health Organization."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"S681","DOI":"10.1046\/j.1440-6047.11.s8.5.x","article-title":"Body mass index as an indicator of obesity","volume":"11","author":"Weisell","year":"2002","journal-title":"Asia Pac. J. Clin. Nutr."},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Joo, H.J., Kim, G.R., Park, E.-C., and Jang, S.-I. (2020). Association between Frequency of breakfast consumption and insulin resistance using triglyceride-glucose index: A Cross-Sectional Study of the Korea National Health and nutrition examination survey (2016\u20132018). Int. J. Environ. Res. Public Health, 17.","DOI":"10.3390\/ijerph17093322"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.nut.2018.11.016","article-title":"Dietary inflammatory index is positively associated with serum high-sensitivity C-reactive protein in a Korean adult population","volume":"63","author":"Shin","year":"2019","journal-title":"Nutrition"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.euroneuro.2017.06.010","article-title":"Association between high sensitivity CRP and suicidal ideation in the Korean general population","volume":"27","author":"Park","year":"2017","journal-title":"Eur. Neuropsychopharmacol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"3631445","DOI":"10.1155\/2021\/3631445","article-title":"Relationship between low vegetable consumption, increased high-sensitive C-reactive protein level, and cardiometabolic risk in Korean adults with Tae-eumin: A cross-sectional study","volume":"2021","author":"Kim","year":"2021","journal-title":"Evid.-Based Complement. Altern. Med."},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Jeong, S., Lee, H., Jung, S., Kim, J.Y., and Park, S. (2023). Higher energy consumption in the evening is associated with increased odds of obesity and metabolic syndrome: Findings from the 2016-2018 Korea National Health and Nutrition Examination Survey (7th KNHANES). Epidemiol. Health, 45.","DOI":"10.4178\/epih.e2023087"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"266","DOI":"10.4162\/nrp.2011.5.3.266","article-title":"Nutritional intake of Korean population before and after adjusting for within-individual variations: 2001 Korean National Health and Nutrition Survey Data","volume":"5","author":"Kim","year":"2011","journal-title":"Nutr. Res. Pract."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Keating, X.D., Zhou, K., Liu, X., Hodges, M., Liu, J., Guan, J., Phelps, A., and Castro-Pi\u00f1ero, J. (2019). Reliability and concurrent validity of global physical activity questionnaire (GPAQ): A systematic review. Int. J. Environ. Res. Public Health, 16.","DOI":"10.3390\/ijerph16214128"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"57","DOI":"10.5114\/hpc.2018.74189","article-title":"Physical activity assessment tools in monitoring physical activity: The Global Physical Activity Questionnaire (GPAQ), the International Physical Activity Questionnaire (IPAQ) or accelerometers\u2013choosing the best tools","volume":"12","author":"Stelmach","year":"2018","journal-title":"Health Probl. Civiliz."},{"key":"ref_50","first-page":"6","article-title":"Developing a simple global physical activity questionnaire for population studies","volume":"9","year":"2002","journal-title":"Australas. Epidemiol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s10389-006-0024-x","article-title":"Development of the world health organization global physical activity questionnaire (GPAQ)","volume":"14","author":"Armstrong","year":"2006","journal-title":"J. Public Health"},{"key":"ref_52","first-page":"221","article-title":"Validity and reliability of the global physical activity questionnaire (GPAQ)","volume":"17","author":"Herrmann","year":"2013","journal-title":"Meas. Phys. Educ."},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Lee, Y.-J., Park, Y.-H., Lee, J.-W., Sung, E.-S., Lee, H.-S., and Park, J. (2022). Household-specific physical activity levels and energy intakes according to the presence of metabolic syndrome in Korean young adults: Korean National Health and nutrition examination survey 2016\u20132018. BMC Public Health, 22.","DOI":"10.1186\/s12889-022-12852-3"},{"key":"ref_54","unstructured":"Physical Activity Guidelines Advisory Committee (2008). Physical Activity Guidelines Advisory Committee Report, 2008, US Department of Health and Human Services."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1249\/MSS.0000000000001946","article-title":"The US physical activity guidelines advisory committee report\u2014Introduction","volume":"51","author":"King","year":"2019","journal-title":"Med. Sci. Sports Exerc."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"e13240","DOI":"10.1097\/MD.0000000000013240","article-title":"Association of muscle strength with cardiovascular risk in Korean adults: Findings from the Korea National Health and Nutrition Examination Survey (KNHANES) VI to VII (2014\u20132016)","volume":"97","author":"Lee","year":"2018","journal-title":"Medicine"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1093\/ageing\/afr051","article-title":"A review of the measurement of grip strength in clinical and epidemiological studies: Towards a standardised approach","volume":"40","author":"Roberts","year":"2011","journal-title":"Age Ageing"},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Kim, C.R., Jeon, Y.-J., Kim, M.C., Jeong, T., and Koo, W.R. (2018). Reference values for hand grip strength in the South Korean population. PLoS ONE, 13.","DOI":"10.1371\/journal.pone.0195485"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"868","DOI":"10.3346\/jkms.2017.32.5.868","article-title":"Mean hand grip strength and cut-off value for sarcopenia in Korean adults using KNHANES VI","volume":"32","author":"Yoo","year":"2017","journal-title":"J. Korean Med. Sci."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"104181","DOI":"10.1016\/j.archger.2020.104181","article-title":"Association between relative hand-grip strength and chronic cardiometabolic and musculoskeletal diseases in Koreans: A cross-sectional study","volume":"92","author":"Kim","year":"2021","journal-title":"Arch. Gerontol. Geriatr."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"207","DOI":"10.2337\/diacare.29.02.06.dc05-1903","article-title":"Whole-grain, bran, and cereal fiber intakes and markers of systemic inflammation in diabetic women","volume":"29","author":"Qi","year":"2006","journal-title":"Diabetes Care"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/1758-5996-6-66","article-title":"Fiber intake and inflammation in type 1 diabetes","volume":"6","author":"Bernaud","year":"2014","journal-title":"Diabetol. Metab. Syndr."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"117","DOI":"10.3329\/bjms.v11i2.11434","article-title":"Association of dietary fiber with high sensitivity C-reactive proteinin type 2 diabetes mellitus","volume":"11","author":"Begum","year":"2012","journal-title":"Bangladesh J. Med. Sci."},{"key":"ref_64","first-page":"5","article-title":"Association between dietary macronutrient intake and high-sensitivity C-reactive protein levels among obese women in Kuantan, Malaysia","volume":"24","author":"Shahadan","year":"2020","journal-title":"Makara J. Sci."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"e33357","DOI":"10.1097\/MD.0000000000033357","article-title":"Dietary fiber intake associated with risk of rheumatoid arthritis among US adults: NHANES 2010\u20132020","volume":"102","author":"Liu","year":"2023","journal-title":"Medicine"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1093\/nutrit\/nuz072","article-title":"Dietary fiber and its associations with depression and inflammation","volume":"78","author":"Swann","year":"2020","journal-title":"Nutr. Rev."},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"Bishehsari, F., Engen, P.A., Preite, N.Z., Tuncil, Y.E., Naqib, A., Shaikh, M., Rossi, M., Wilber, S., Green, S.J., and Hamaker, B.R. (2018). Dietary fiber treatment corrects the composition of gut microbiota, promotes SCFA production, and suppresses colon carcinogenesis. Genes, 9.","DOI":"10.3390\/genes9020102"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"272S","DOI":"10.1093\/jn\/130.2.272S","article-title":"Dietary fiber and energy regulation","volume":"130","year":"2000","journal-title":"J. Nutr."},{"key":"ref_69","first-page":"409","article-title":"Influence of a high-fibre food (myco-protein*) on appetite: Effects on satiation (within meals) and satiety (following meals)","volume":"47","author":"Burley","year":"1993","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/j.jhep.2010.12.017","article-title":"C-reactive protein levels in relation to various features of non-alcoholic fatty liver disease among obese patients","volume":"55","author":"Zimmermann","year":"2011","journal-title":"J. Hepatol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"522","DOI":"10.9755\/ejfa.2015-07-521","article-title":"Dietary fiber: An ingredient against obesity","volume":"28","author":"Requena","year":"2016","journal-title":"Emir. J. Food Agric."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.clnu.2010.09.010","article-title":"Hand grip strength: Outcome predictor and marker of nutritional status","volume":"30","author":"Norman","year":"2011","journal-title":"Clin. Nutr."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"101185","DOI":"10.1016\/j.arr.2020.101185","article-title":"Markers of inflammation and their association with muscle strength and mass: A systematic review and meta-analysis","volume":"64","author":"Tuttle","year":"2020","journal-title":"Ageing Res. Rev."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1080\/13697137.2021.1965116","article-title":"Changes in high-sensitivity C-reactive protein levels and metabolic indices according to grip strength in Korean postmenopausal women","volume":"25","author":"Kim","year":"2022","journal-title":"Climacteric"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.1007\/s00394-018-1812-0","article-title":"The combined association of adherence to Mediterranean diet, muscular and cardiorespiratory fitness on low-grade inflammation in adolescents: A pooled analysis","volume":"58","author":"Moreira","year":"2019","journal-title":"Eur. J. Nutr."},{"key":"ref_76","first-page":"23","article-title":"Effects of eight weeks of endurance-resistance training on some inflammatory markers and cardiovascular endurance in sedentary postmenopausal women","volume":"20","author":"Shabani","year":"2017","journal-title":"Iran. J. Obstet. Gynecol. Infertil."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1007\/s00394-012-0450-1","article-title":"Effects of 5% weight loss through diet or diet plus exercise on cardiovascular parameters of obese: A randomized clinical trial","volume":"52","author":"Fayh","year":"2013","journal-title":"Eur. J. Nutr."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1758-5996-4-1","article-title":"Ten-week lifestyle changing program reduces several indicators for metabolic syndrome in overweight adults","volume":"4","author":"Mecca","year":"2012","journal-title":"Diabetol. Metab. Syndr."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1097\/00001648-200209000-00012","article-title":"Does exercise reduce inflammation? Physical activity and C-reactive protein among US adults","volume":"13","author":"Ford","year":"2002","journal-title":"Epidemiology"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ijcard.2004.08.073","article-title":"Exercise training modulates cytokines activity in coronary heart disease patients","volume":"100","author":"Goldhammer","year":"2005","journal-title":"Int. J. Cardiol."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.2337\/dc11-0469","article-title":"Physical activity, high-sensitivity C-reactive protein, and total and cardiovascular disease mortality in type 2 diabetes","volume":"34","author":"Soinio","year":"2011","journal-title":"Diabetes Care"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1038\/oby.2003.145","article-title":"Leisure-time physical activity and reduced plasma levels of obesity-related inflammatory markers","volume":"11","author":"Pischon","year":"2003","journal-title":"Obes. Res."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s40200-015-0181-y","article-title":"Combined association of physical activity and diet with C-reactive protein among smokers","volume":"14","author":"Loprinzi","year":"2015","journal-title":"J. Diabetes Metab. Disord."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1177\/0003319707300014","article-title":"Diet, exercise, and C-reactive protein levels in people with abdominal obesity: The ATTICA epidemiological study","volume":"58","author":"Pitsavos","year":"2007","journal-title":"Angiology"},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"9139","DOI":"10.3390\/nu7115459","article-title":"Definition of the Mediterranean diet: A literature review","volume":"7","author":"Davis","year":"2015","journal-title":"Nutrients"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"330S","DOI":"10.3945\/an.113.005389","article-title":"Mediterranean diet and cardiovascular health: Teachings of the PREDIMED study","volume":"5","author":"Ros","year":"2014","journal-title":"Adv. Nutr."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"2314","DOI":"10.1158\/0008-5472.CAN-11-3092","article-title":"Effects of a caloric restriction weight loss diet and exercise on inflammatory biomarkers in overweight\/obese postmenopausal women: A randomized controlled trial","volume":"72","author":"Imayama","year":"2012","journal-title":"Cancer Res."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"110","DOI":"10.4103\/2008-7802.190608","article-title":"Effects of High Protein and Balanced Diets on Lipid Profiles and Inflammation Biomarkers in Obese and Overweight Women at Aerobic Clubs: A Randomized Clinical Trial","volume":"7","author":"Amini","year":"2016","journal-title":"Int. J. Prev. Med."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.metabol.2009.07.008","article-title":"Changes in C-reactive protein from low-fat diet and\/or physical activity in men and women with and without metabolic syndrome","volume":"59","author":"Camhi","year":"2010","journal-title":"Metabolism"},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"S139","DOI":"10.1016\/j.enfcli.2020.12.009","article-title":"Association between sitting time and high-sensitivity C-reactive protein level among obese women","volume":"31","author":"Daud","year":"2021","journal-title":"Enferm. Clin."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1017\/S0007114520002391","article-title":"Diet and sedentary behaviour in relation to mortality in US adults with a cardiovascular condition: Results from the National Health and Nutrition Examination Survey linked to the US mortality registry","volume":"124","author":"Ricci","year":"2020","journal-title":"Br. J. Nutr."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1007\/s00394-018-1764-4","article-title":"Diet as a moderator in the association of sedentary behaviors with inflammatory biomarkers among adolescents in the HELENA study","volume":"58","author":"Arouca","year":"2019","journal-title":"Eur. J. Nutr."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"40","DOI":"10.25220\/WNJ.V05.i1.0006","article-title":"Dietary Fiber\u2019s Effect on High Sensitivity C-reactive Protein Serum in Sedentary Workers","volume":"5","author":"Saputra","year":"2021","journal-title":"World Nutr. 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