{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:00:18Z","timestamp":1787029218436,"version":"build-2736575974"},"reference-count":70,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2024,4,9]],"date-time":"2024-04-09T00:00:00Z","timestamp":1712620800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Riddet Institute","award":["RM18873"],"award-info":[{"award-number":["RM18873"]}]},{"name":"Zespri International","award":["RM18873"],"award-info":[{"award-number":["RM18873"]}]},{"name":"Alpha Group Holdings","award":["RM18873"],"award-info":[{"award-number":["RM18873"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Kiwifruit (KF) has shown neuroprotective potential in cell-based and rodent models by augmenting the capacity of endogenous antioxidant systems. This study aimed to determine whether KF consumption modulates the antioxidant capacity of plasma and brain tissue in growing pigs. Eighteen male pigs were divided equally into three groups: (1) bread, (2) bread + Actinidia deliciosa cv. \u2018Hayward\u2019 (green-fleshed), and (3) bread + A. chinensis cv. \u2018Hort16A\u2019 (yellow-fleshed). Following consumption of the diets for eight days, plasma and brain tissue (brain stem, corpus striatum, hippocampus, and prefrontal cortex) were collected and measured for biomarkers of antioxidant capacity, enzyme activity, and protein expression assessments. Green KF significantly increased ferric-reducing antioxidant potential (FRAP) in plasma and all brain regions compared with the bread-only diet. Gold KF increased plasma ascorbate concentration and trended towards reducing acetylcholinesterase activity in the brain compared with the bread-only diet. Pearson correlation analysis revealed a significant positive correlation between FRAP in the brain stem, prefrontal cortex, and hippocampus with the total polyphenol concentration of dietary interventions. These findings provide exploratory evidence for the benefits of KF constituents in augmenting the brain\u2019s antioxidant capacity that may support neurological homeostasis during oxidative stress.<\/jats:p>","DOI":"10.3390\/nu16081097","type":"journal-article","created":{"date-parts":[[2024,4,9]],"date-time":"2024-04-09T08:55:12Z","timestamp":1712652912000},"page":"1097","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of Green and Gold Kiwifruit Varieties on Antioxidant Neuroprotective Potential in Pigs as a Model for Human Adults"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2918-1602","authenticated-orcid":false,"given":"Alexander P.","family":"Kanon","sequence":"first","affiliation":[{"name":"School of Health Sciences, College of Health, Massey University, Palmerston North 4442, New Zealand"},{"name":"Riddet Institute, Massey University, Te Ohu Rangahau Kai Facility, Palmerston North 4442, New Zealand"},{"name":"Alpha-Massey Natural Nutraceutical Research Centre, Massey University, Palmerston North 4442, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5612-1918","authenticated-orcid":false,"given":"Caroline","family":"Giezenaar","sequence":"additional","affiliation":[{"name":"Riddet Institute, Massey University, Te Ohu Rangahau Kai Facility, Palmerston North 4442, New Zealand"},{"name":"Food Experience and Sensory Testing Laboratory, School of Food and Advanced Technology, Palmerston North 4410, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6744-9705","authenticated-orcid":false,"given":"Nicole C.","family":"Roy","sequence":"additional","affiliation":[{"name":"Riddet Institute, Massey University, Te Ohu Rangahau Kai Facility, Palmerston North 4442, New Zealand"},{"name":"Department of Human Nutrition, University of Otago, Dunedin 9016, New Zealand"},{"name":"High-Value Nutrition National Science Challenge, Auckland 1023, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isuri A.","family":"Jayawardana","sequence":"additional","affiliation":[{"name":"Riddet Institute, Massey University, Te Ohu Rangahau Kai Facility, Palmerston North 4442, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7031-7180","authenticated-orcid":false,"given":"Dominic","family":"Lomiwes","sequence":"additional","affiliation":[{"name":"Immune Health and Physical Performance, Nutrition and Health Group, The New Zealand Institute for Plant and Food Research Limited, Palmerston North 4410, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos A.","family":"Montoya","sequence":"additional","affiliation":[{"name":"Riddet Institute, Massey University, Te Ohu Rangahau Kai Facility, Palmerston North 4442, New Zealand"},{"name":"Smart Foods and Bioproducts, AgResearch Ltd., Te Ohu Rangahau Kai Facility, Palmerston North 4442, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2514-6551","authenticated-orcid":false,"given":"Warren C.","family":"McNabb","sequence":"additional","affiliation":[{"name":"Riddet Institute, Massey University, Te Ohu Rangahau Kai Facility, Palmerston North 4442, New Zealand"},{"name":"High-Value Nutrition National Science Challenge, Auckland 1023, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon J.","family":"Henare","sequence":"additional","affiliation":[{"name":"School of Health Sciences, College of Health, Massey University, Palmerston North 4442, New Zealand"},{"name":"Riddet Institute, Massey University, Te Ohu Rangahau Kai Facility, Palmerston North 4442, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1080\/01616412.2016.1251711","article-title":"Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders","volume":"39","author":"Islam","year":"2017","journal-title":"Neurol. 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