{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T02:02:59Z","timestamp":1790128979456,"version":"4.0.1"},"reference-count":60,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T00:00:00Z","timestamp":1716940800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: Recently, many studies have been devoted to discovering nutrients for exercise-like effects. Resistance exercise and the intake of essential amino acids (EAAs) are known to be factors that can affect muscle mass and strength improvement. The purpose of this study was to investigate changes in muscle quality, myokines, and inflammation in response to resistance exercise and EAA supplementation. Methods: Thirty-four males volunteered to participate in this study. They were assigned to four groups: (1) placebo (CO), (2) resistance exercise (RE), (3) EAA supplementation, and (4) RE + EAA supplementation. Body composition, muscle quality, myokines, and inflammation were measured at baseline and four weeks after treatment. Results: Lean body fat had decreased in both RE and RE + EAA groups. Lean body mass had increased in only the RE + EAA group. In all groups except for CO, irisin, myostatin A, and TNF-\u03b1 levels had decreased. The grip strength of the right hand and trunk flexion peak torque increased in the RE group. The grip strength of the left hand, trunk flexion peak torque, and knee flexion peak torque of the left leg were increased in RE + EAA. Conclusions: RE, EAA, and RE + EAA could effectively improve the muscle quality, myokine, and inflammation factors of young adult males. This finding highlights the importance of resistance exercise and amino acid intake.<\/jats:p>","DOI":"10.3390\/nu16111688","type":"journal-article","created":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T03:45:08Z","timestamp":1717040708000},"page":"1688","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Effects of Resistance Exercise and Essential Amino Acid Intake on Muscle Quality, Myokine, and Inflammation Factors in Young Adult Males"],"prefix":"10.3390","volume":"16","author":[{"given":"Deokhwa","family":"Jeong","sequence":"first","affiliation":[{"name":"Department of Smart Health Science and Technology, Kangwon National University, Chuncheon 24341, Gangwon-do, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyumin","family":"Park","sequence":"additional","affiliation":[{"name":"Center for Sports Science in Gangwon, Chuncheon 24239, Gangwon-do, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1142-0740","authenticated-orcid":false,"given":"Jinseok","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Sport Science, Kangwon National University, Chuncheon 24341, Gangwon-do, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiye","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Smart Health Science and Technology, Kangwon National University, Chuncheon 24341, Gangwon-do, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haifeng","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Smart Health Science and Technology, Kangwon National University, Chuncheon 24341, Gangwon-do, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyeongmo","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Sport Science, Kangwon National University, Chuncheon 24341, Gangwon-do, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangliang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Sport Science, Kangwon National University, Chuncheon 24341, Gangwon-do, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Sakai","sequence":"additional","affiliation":[{"name":"Chemicals & Life Science Division, Nagase Korea Corporation, Seoul 04527, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunghwun","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Smart Health Science and Technology, Kangwon National University, Chuncheon 24341, Gangwon-do, Republic of Korea"},{"name":"Department of Sport Science, Kangwon National University, Chuncheon 24341, Gangwon-do, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,5,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1186\/s12889-023-15833-2","article-title":"Effect of the COVID-19 pandemic on obesity and its risk factors: A systematic review","volume":"23","author":"Nour","year":"2023","journal-title":"BMC Public Health"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1139\/h04-008","article-title":"The economic costs associated with physical inactivity and obesity in Canada: An update","volume":"29","author":"Katzmarzyk","year":"2004","journal-title":"Can. 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