{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T13:56:36Z","timestamp":1789826196341,"version":"4.0.1"},"reference-count":140,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T00:00:00Z","timestamp":1718668800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Kidney stone disease has a multifactorial etiology, and evolving dietary habits necessitate continuous updates on the impact of dietary components on lithogenesis. The relationship between diseases influenced by lifestyle, such as obesity and diabetes, and kidney stone risk underscores the need for comprehensive lifestyle analysis. Effective management of kidney stones requires a multidisciplinary approach, involving collaboration among nutritionists, urologists, nephrologists, and other healthcare professionals to address the complex interactions between diet, lifestyle, and individual susceptibility. Personalized dietary therapy, based on each patient\u2019s unique biochemical and dietary profile, is essential and necessitates comprehensive nutritional assessments. Accurate dietary intake evaluation is best achieved through seven-day, real-time dietary records. Key factors influencing urinary risk include fluid intake, dietary protein, carbohydrates, oxalate, calcium, and sodium chloride. Personalized interventions, such as customized dietary changes based on gut microbiota, may improve stone prevention and recurrence. Current research suggests individualized guidance on alcohol intake and indicates that tea and coffee consumption might protect against urolithiasis. There is potential evidence linking tobacco use and secondhand smoke to increased kidney stone risk. The effects of vitamins and physical activity on kidney stone risk remain unresolved due to mixed evidence. For diseases influenced by lifestyle, conclusive evidence on targeted interventions for nephrolithiasis prevention is lacking, though preliminary research suggests potential benefits. Management strategies emphasize lifestyle modifications to reduce recurrence risks, support rapid recovery, and identify predisposing conditions, highlighting the importance of these changes despite inconclusive data.<\/jats:p>","DOI":"10.3390\/nu16121932","type":"journal-article","created":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T04:21:28Z","timestamp":1718770888000},"page":"1932","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["The Multidisciplinary Approach in the Management of Patients with Kidney Stone Disease\u2014A State-of-the-Art Review"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8706-1927","authenticated-orcid":false,"given":"Krzysztof","family":"Balawender","sequence":"first","affiliation":[{"name":"Institute of Medical Sciences, Medical College of Rzeszow University, Al. mjr. W. Kopisto 2a, 35-959 Rzeszow, Poland"},{"name":"Clinical Department of Urology and Urological Oncology, Municipal Hospital, Rycerska 4, 35-241 Rzeszow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4619-7705","authenticated-orcid":false,"given":"Edyta","family":"\u0141uszczki","sequence":"additional","affiliation":[{"name":"Institute of Health Sciences, Medical College of Rzeszow University, Al. mjr. W. Kopisto 2a, 35-959 Rzeszow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5393-3515","authenticated-orcid":false,"given":"Artur","family":"Mazur","sequence":"additional","affiliation":[{"name":"Institute of Medical Sciences, Medical College of Rzeszow University, Al. mjr. W. Kopisto 2a, 35-959 Rzeszow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5786-6214","authenticated-orcid":false,"given":"Justyna","family":"Wyszy\u0144ska","sequence":"additional","affiliation":[{"name":"Institute of Health Sciences, Medical College of Rzeszow University, Al. mjr. W. Kopisto 2a, 35-959 Rzeszow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Yuan, T., Xia, Y., Li, B., Yu, W., Rao, T., Ye, Z., Yan, X., Song, B., Li, L., and Lin, F. (2023). Gut microbiota in patients with kidney stones: A systematic review and meta-analysis. BMC Microbiol., 23.","DOI":"10.1186\/s12866-023-02891-0"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1097\/JU.0000000000001629","article-title":"Beyond Prevalence: Annual Cumulative Incidence of Kidney Stones in the United States","volume":"205","author":"Tundo","year":"2021","journal-title":"J. Urol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1097\/JU.0000000000002331","article-title":"Incidence of Kidney Stones in the United States: The Continuous National Health and Nutrition Examination Survey","volume":"207","author":"Hill","year":"2022","journal-title":"J. Urol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.juro.2016.12.135","article-title":"The Risk of Chronic Kidney Disease Associated with Urolithiasis and its Urological Treatments: A Review","volume":"198","author":"Gambaro","year":"2017","journal-title":"J. Urol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"3155","DOI":"10.1007\/s00198-016-3658-8","article-title":"Nephrolithiasis, bone mineral density, osteoporosis, and fractures: A systematic review and comparative meta-analysis","volume":"27","author":"Lucato","year":"2016","journal-title":"Osteoporos. Int."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1016\/j.juro.2016.11.097","article-title":"Validation and Reliability of the Wisconsin Stone Quality of Life Questionnaire","volume":"197","author":"Penniston","year":"2017","journal-title":"J. Urol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1111\/iju.12865","article-title":"Increased risk of anxiety among patients with urolithiasis: A nationwide population-based cohort study","volume":"22","author":"Lien","year":"2015","journal-title":"Int. J. Urol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1159\/000052367","article-title":"Course of calcium stone disease without treatment. What can we expect?","volume":"37","author":"Strohmaier","year":"2000","journal-title":"Eur. Urol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0140-6736(06)68071-9","article-title":"Kidney stones: Pathophysiology and medical management","volume":"367","author":"Moe","year":"2006","journal-title":"Lancet"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1097\/01.JAA.0000522145.52305.aa","article-title":"Urolithiasis and nephrolithiasis","volume":"30","author":"Chung","year":"2017","journal-title":"J. Am. Acad. Physician Assist."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/qjmed\/hcu195","article-title":"The risk of kidney cancer in patients with kidney stones: A systematic review and meta-analysis","volume":"108","author":"Cheungpasitporn","year":"2015","journal-title":"QJM"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.eururo.2014.06.036","article-title":"Use of the National Health and Nutrition Examination Survey to calculate the impact of obesity and diabetes on cost and prevalence of urolithiasis in 2030","volume":"66","author":"Antonelli","year":"2014","journal-title":"Eur. Urol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1111\/j.1523-1755.2005.00599.x","article-title":"Direct and indirect costs of nephrolithiasis in an employed population: Opportunity for disease management?","volume":"68","author":"Saigal","year":"2005","journal-title":"Kidney Int."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1111\/bju.14991","article-title":"Evaluation of the economic burden of kidney stone disease in the UK: A retrospective cohort study with a mean follow-up of 19 years","volume":"125","author":"Geraghty","year":"2020","journal-title":"BJU Int."},{"key":"ref_15","first-page":"486","article-title":"An exaggerated augmentation of renal calcium excretion after oral glucose ingestion in patients with renal hypercalciuria","volume":"15","author":"Barilla","year":"1978","journal-title":"Investig. Urol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1038\/sj.ki.5001656","article-title":"Diet and fluid prescription in stone disease","volume":"70","author":"Taylor","year":"2006","journal-title":"Kidney Int."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1681\/ASN.2009030276","article-title":"DASH-style diet associates with reduced risk for kidney stones","volume":"20","author":"Taylor","year":"2009","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.clnesp.2020.06.021","article-title":"The association of Dietary Approaches to Stop Hypertension-style diet with urinary risk factors of kidney stones formation in men with nephrolithiasis","volume":"39","author":"Maddahi","year":"2020","journal-title":"Clin. Nutr. ESPEN"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1056\/NEJMoa010369","article-title":"Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria","volume":"346","author":"Borghi","year":"2002","journal-title":"N. Engl. J. Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1038\/sj.ejcn.1601901","article-title":"Fluid intake and epidemiology of urolithiasis","volume":"57","author":"Siener","year":"2003","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1097\/MNH.0000000000000581","article-title":"Occupational kidney stones","volume":"29","author":"Malieckal","year":"2020","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s00240-013-0579-2","article-title":"The effect of work location on urolithiasis in health care professionals","volume":"41","author":"Linder","year":"2013","journal-title":"Urolithiasis"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"535","DOI":"10.7326\/0003-4819-158-7-201304020-00005","article-title":"Medical management to prevent recurrent nephrolithiasis in adults: A systematic review for an American College of Physicians Clinical Guideline","volume":"158","author":"Fink","year":"2013","journal-title":"Ann. Intern. Med."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"659","DOI":"10.7326\/M13-2908","article-title":"Dietary and pharmacologic management to prevent recurrent nephrolithiasis in adults: A clinical practice guideline from the American College of Physicians","volume":"161","author":"Qaseem","year":"2014","journal-title":"Ann. Intern. Med."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Lin, B.B., Lin, M.E., Huang, R.H., Hong, Y.K., Lin, B.L., and He, X.J. (2020). Dietary and lifestyle factors for primary prevention of nephrolithiasis: A systematic review and meta-analysis. BMC Nephrol., 21.","DOI":"10.1186\/s12882-020-01925-3"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.juro.2014.05.006","article-title":"Medical management of kidney stones: AUA guideline","volume":"192","author":"Pearle","year":"2014","journal-title":"J. Urol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/S0022-5347(05)67633-1","article-title":"Medical treatment of cystinuria: Critical reappraisal of long-term results","volume":"163","author":"Barbey","year":"2000","journal-title":"J. Urol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1111\/bju.14871","article-title":"Water to prevent kidney stones: Tap vs bottled; soft vs hard\u2014does it matter?","volume":"124","author":"Willis","year":"2019","journal-title":"BJU Int."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1289\/ehp.0900782","article-title":"Relationship between tap water hardness, magnesium, and calcium concentration and mortality due to ischemic heart disease or stroke in The Netherlands","volume":"118","author":"Leurs","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s00240-015-0844-7","article-title":"Can the manipulation of urinary pH by beverages assist with the prevention of stone recurrence?","volume":"44","author":"Siener","year":"2016","journal-title":"Urolithiasis"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1017\/S0007114500002488","article-title":"Cross-over study of the influence of bicarbonate-rich mineral water on urinary composition in comparison with sodium potassium citrate in healthy male subjects","volume":"84","author":"Kessler","year":"2000","journal-title":"Br. J. Nutr."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Cheraghian, B., Meysam, A., Hashemi, S.J., Hosseini, S.A., Malehi, A.S., Khazaeli, D., and Rahimi, Z. (2024). Kidney stones and dietary intake in adults: A population-based study in southwest Iran. BMC Public Health, 24.","DOI":"10.1186\/s12889-024-18393-1"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s00345-007-0144-0","article-title":"Clinical study on the effect of mineral waters containing bicarbonate on the risk of urinary stone formation in patients with multiple episodes of CaOx-urolithiasis","volume":"25","author":"Smorag","year":"2007","journal-title":"World J. Urol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.29219\/fnr.v63.3515","article-title":"Effects of mineral waters on acid-base status in healthy adults: Results of a randomized trial","volume":"63","author":"Wasserfurth","year":"2019","journal-title":"Food Nutr. Res."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1089\/end.2020.0677","article-title":"Variations in the Mineral Content of Bottled \"Still\" Water Across Europe: Comparison of 182 Brands Across 10 Countries","volume":"35","author":"Stoots","year":"2021","journal-title":"J. Endourol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.2215\/CJN.11661112","article-title":"Soda and other beverages and the risk of kidney stones","volume":"8","author":"Ferraro","year":"2013","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Barghouthy, Y., and Somani, B.K. (2021). Role of Citrus Fruit Juices in Prevention of Kidney Stone Disease (KSD): A Narrative Review. Nutrients, 13.","DOI":"10.3390\/nu13114117"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1089\/end.2020.0031","article-title":"Using Low-Calorie Orange Juice as a Dietary Alternative to Alkali Therapy","volume":"34","author":"Large","year":"2020","journal-title":"J. Endourol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1093\/ndt\/gfad188","article-title":"The basics of phosphate metabolism","volume":"39","author":"Wagner","year":"2024","journal-title":"Nephrol. Dial. Transplant."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1681\/ASN.2013101085","article-title":"Mutations in SLC34A3\/NPT2c are associated with kidney stones and nephrocalcinosis","volume":"25","author":"Dasgupta","year":"2014","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1053\/ajkd.2002.34504","article-title":"Effect of low-carbohydrate high-protein diets on acid-base balance, stone-forming propensity, and calcium metabolism","volume":"40","author":"Reddy","year":"2002","journal-title":"Am. J. Kidney Dis."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.2215\/CJN.01520216","article-title":"Dietary Protein and Potassium, Diet-Dependent Net Acid Load, and Risk of Incident Kidney Stones","volume":"11","author":"Ferraro","year":"2016","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1007\/s00394-023-03143-7","article-title":"Protein intake and risk of urolithiasis and kidney diseases: An umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society","volume":"62","author":"Remer","year":"2023","journal-title":"Eur. J. Nutr."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1046\/j.1464-410x.2000.00511.x","article-title":"The dietary habits of idiopathic calcium stone-formers and normal control subjects","volume":"85","author":"Norman","year":"2000","journal-title":"BJU Int."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.juro.2010.09.074","article-title":"Effect of n-3 fatty acid supplementation on urinary risk factors for calcium oxalate stone formation","volume":"185","author":"Siener","year":"2011","journal-title":"J. Urol."},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Rodgers, A.L., and Siener, R. (2020). The Efficacy of Polyunsaturated Fatty Acids as Protectors against Calcium Oxalate Renal Stone Formation: A Review. Nutrients, 12.","DOI":"10.3390\/nu12041069"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1001\/archinte.164.8.885","article-title":"Dietary factors and the risk of incident kidney stones in younger women: Nurses\u2019 Health Study II","volume":"164","author":"Curhan","year":"2004","journal-title":"Arch. Intern. Med."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"3225","DOI":"10.1097\/01.ASN.0000146012.44570.20","article-title":"Dietary factors and the risk of incident kidney stones in men: New insights after 14 years of follow-up","volume":"15","author":"Taylor","year":"2004","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.1210\/jc.2013-1301","article-title":"Hyperinsulinemia and urinary calcium excretion in calcium stone formers with idiopathic hypercalciuria","volume":"98","author":"Yoon","year":"2013","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Johnson, R.J., Perez-Pozo, S.E., Lillo, J.L., Grases, F., Schold, J.D., Kuwabara, M., Sato, Y., Hernando, A.A., Garcia, G., and Jensen, T. (2018). Fructose increases risk for kidney stones: Potential role in metabolic syndrome and heat stress. BMC Nephrol., 19.","DOI":"10.1186\/s12882-018-1105-0"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1111\/j.1523-1755.2004.00975.x","article-title":"Rapid Communication: Relative effect of urinary calcium and oxalate on saturation of calcium oxalate","volume":"66","author":"Pak","year":"2004","journal-title":"Kidney Int."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/S0302-2838(03)00317-8","article-title":"Prospective study on the efficacy of a selective treatment and risk factors for relapse in recurrent calcium oxalate stone patients","volume":"44","author":"Siener","year":"2003","journal-title":"Eur. Urol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1186\/1479-5876-11-306","article-title":"Dietary hyperoxaluria is not reduced by treatment with lactic acid bacteria","volume":"11","author":"Siener","year":"2013","journal-title":"J. Transl. Med."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.1681\/ASN.2007020219","article-title":"Oxalate intake and the risk for nephrolithiasis","volume":"18","author":"Taylor","year":"2007","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1016\/j.juro.2013.03.074","article-title":"Dietary calcium from dairy and nondairy sources, and risk of symptomatic kidney stones","volume":"190","author":"Taylor","year":"2013","journal-title":"J. Urol."},{"key":"ref_56","first-page":"235","article-title":"Calcium intake and urinary stone disease","volume":"3","author":"Sorensen","year":"2014","journal-title":"Transl. Androl. Urol."},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Siener, R. (2021). Nutrition and Kidney Stone Disease. Nutrients, 13.","DOI":"10.3390\/nu13061917"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"951","DOI":"10.3390\/nu3110951","article-title":"Higher urinary sodium, a proxy for intake, is associated with increased calcium excretion and lower hip bone density in healthy young women with lower calcium intakes","volume":"3","author":"Bedford","year":"2011","journal-title":"Nutrients"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"565","DOI":"10.3945\/ajcn.2009.28614","article-title":"Effects of a low-salt diet on idiopathic hypercalciuria in calcium-oxalate stone formers: A 3-mo randomized controlled trial","volume":"91","author":"Nouvenne","year":"2010","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.juro.2011.03.006","article-title":"Impact of dietary calcium and oxalate, and Oxalobacter formigenes colonization on urinary oxalate excretion","volume":"186","author":"Jiang","year":"2011","journal-title":"J. Urol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/bju.14840","article-title":"Association of intestinal oxalate-degrading bacteria with recurrent calcium kidney stone formation and hyperoxaluria: A case-control study","volume":"125","author":"Tavasoli","year":"2020","journal-title":"BJU Int."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1038\/sj.ki.5000162","article-title":"Oxalobacter sp. reduces urinary oxalate excretion by promoting enteric oxalate secretion","volume":"69","author":"Hatch","year":"2006","journal-title":"Kidney Int."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"1156097","DOI":"10.3389\/fpubh.2023.1156097","article-title":"Association between alcohol consumption and kidney stones in American adults: 2007\u20132016 NHANES","volume":"11","author":"Zhou","year":"2023","journal-title":"Front. Public. Health"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00240-023-01472-0","article-title":"Association between alcohol and urolithiasis: A mendelian randomization study","volume":"51","author":"Yang","year":"2023","journal-title":"Urolithiasis"},{"key":"ref_65","doi-asserted-by":"crossref","unstructured":"Kim, S.Y., Yoo, D.M., Bang, W.J., and Choi, H.G. (2022). Obesity Is Positively Associated and Alcohol Intake Is Negatively Associated with Nephrolithiasis. Nutrients, 14.","DOI":"10.3390\/nu14194122"},{"key":"ref_66","doi-asserted-by":"crossref","unstructured":"Wang, H., Fan, J., Yu, C., Guo, Y., Pei, P., Yang, L., Chen, Y., Du, H., Meng, F., and Chen, J. (2021). Consumption of Tea, Alcohol, and Fruits and Risk of Kidney Stones: A Prospective Cohort Study in 0.5 Million Chinese Adults. Nutrients, 13.","DOI":"10.3390\/nu13041119"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s10654-014-9904-5","article-title":"Diet and risk of kidney stones in the Oxford cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC)","volume":"29","author":"Turney","year":"2014","journal-title":"Eur. J. Epidemiol."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1159\/000365358","article-title":"Systematic review and meta-analysis of the effect of alcohol intake on the risk of urolithiasis including dose-response relationship","volume":"94","author":"Wang","year":"2015","journal-title":"Urol. Int."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1097\/01.ju.0000129413.87024.5c","article-title":"Acute caffeine effects on urine composition and calcium kidney stone risk in calcium stone formers","volume":"172","author":"Massey","year":"2004","journal-title":"J. Urol."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"2683","DOI":"10.1007\/s00394-019-02115-0","article-title":"Caffeine intake and the risk of recurrent kidney stones in adults, an analysis of 2007-2014 National Health and Nutrition Examination Surveys","volume":"59","author":"Sun","year":"2020","journal-title":"Eur. J. Nutr."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1093\/hmg\/ddz061","article-title":"A genome-wide association study of bitter and sweet beverage consumption","volume":"28","author":"Zhong","year":"2019","journal-title":"Hum. Mol. Genet."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1053\/j.ajkd.2021.04.018","article-title":"Coffee and Caffeine Consumption and Risk of Kidney Stones: A Mendelian Randomization Study","volume":"79","author":"Yuan","year":"2022","journal-title":"Am. J. Kidney Dis."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1007\/s11255-022-03295-1","article-title":"Caffeine intake and the risk of incident kidney stones: A systematic review and meta-analysis","volume":"54","author":"Zhao","year":"2022","journal-title":"Int. Urol. Nephrol."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"38536","DOI":"10.1038\/srep38536","article-title":"Caffeine prevents kidney stone formation by translocation of apical surface annexin A1 crystal-binding protein into cytoplasm: In vitro evidence","volume":"6","author":"Peerapen","year":"2016","journal-title":"Sci. Rep."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.3945\/ajcn.114.089987","article-title":"Caffeine intake and the risk of kidney stones","volume":"100","author":"Ferraro","year":"2014","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"831","DOI":"10.2116\/analsci.31.831","article-title":"Simultaneous Determination of Trigonelline, Caffeine, Chlorogenic Acid and Their Related Compounds in Instant Coffee Samples by HPLC Using an Acidic Mobile Phase Containing Octanesulfonate","volume":"31","author":"Arai","year":"2015","journal-title":"Anal. Sci."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1007\/s00345-020-03466-8","article-title":"Tea and coffee consumption and pathophysiology related to kidney stone formation: A systematic review","volume":"39","author":"Barghouthy","year":"2021","journal-title":"World J. Urol."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"111919","DOI":"10.1016\/j.nut.2022.111919","article-title":"Tea intake and risk of kidney stones: A mendelian randomization study","volume":"107","author":"Liu","year":"2023","journal-title":"Nutrition"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1021\/mp700075m","article-title":"Biotransformation of green tea polyphenols and the biological activities of those metabolites","volume":"4","author":"Lambert","year":"2007","journal-title":"Mol. Pharm."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s00775-016-1344-0","article-title":"EGCG decreases binding of calcium oxalate monohydrate crystals onto renal tubular cells via decreased surface expression of alpha-enolase","volume":"21","author":"Kanlaya","year":"2016","journal-title":"J. Biol. Inorg. Chem."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/iju.13849","article-title":"Green tea intake and risk of incident kidney stones: Prospective cohort studies in middle-aged and elderly Chinese individuals","volume":"26","author":"Shu","year":"2019","journal-title":"Int. J. Urol."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"1218051","DOI":"10.3389\/fmed.2023.1218051","article-title":"Associations between smoke exposure and kidney stones: Results from the NHANES (2007\u20132018) and Mendelian randomization analysis","volume":"10","author":"Huang","year":"2023","journal-title":"Front. Med."},{"key":"ref_83","doi-asserted-by":"crossref","unstructured":"Chen, Y.H., Lee, J.I., Shen, J.T., Wu, Y.H., Tsao, Y.H., Jhan, J.H., Wang, H.S., Lee, Y.C., Huang, S.P., and Chen, S.C. (2023). The impact of secondhand smoke on the development of kidney stone disease is not inferior to that of smoking: A longitudinal cohort study. BMC Public Health, 23.","DOI":"10.1186\/s12889-023-16116-6"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1001\/jamainternmed.2013.2296","article-title":"Ascorbic acid supplements and kidney stone incidence among men: A prospective study","volume":"173","author":"Thomas","year":"2013","journal-title":"JAMA Intern. Med."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1007\/s00240-023-01423-9","article-title":"Evaluating the American Urologic Association (AUA) dietary recommendations for kidney stone management using the National Health And Nutritional Examination Survey (NHANES)","volume":"51","author":"Labagnara","year":"2023","journal-title":"Urolithiasis"},{"key":"ref_86","doi-asserted-by":"crossref","unstructured":"Zeng, H., Liu, Z., He, Y., Chen, H., He, J., Liu, M., Wu, S., He, H., Huang, C., and Xu, R. (2024). Multivitamins co-intake can reduce the prevalence of kidney stones: A large-scale cross-sectional study. Int. Urol. Nephrol., 1\u201311.","DOI":"10.1007\/s11255-024-04021-9"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1292\/jvms.17-0083","article-title":"Combination of vitamin E and vitamin C alleviates renal function in hyperoxaluric rats via antioxidant activity","volume":"79","author":"Jaturakan","year":"2017","journal-title":"J. Vet. Med. Sci."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.metabol.2008.09.023","article-title":"Oxalic acid excretion after intravenous ascorbic acid administration","volume":"58","author":"Robitaille","year":"2009","journal-title":"Metabolism"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/bju.12642","article-title":"Oxalate at physiological urine concentrations induces oxidative injury in renal epithelial cells: Effect of \u03b1-tocopherol and ascorbic acid","volume":"114","author":"Thamilselvan","year":"2014","journal-title":"BJU Int."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1590\/s1677-5538.ibju.2017.0656","article-title":"Vitamin C inhibits crystallization of struvite from artificial urine in the presence of Pseudomonas aeruginosa","volume":"44","author":"Manzoor","year":"2018","journal-title":"Int. Braz. J. Urol."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1681\/ASN.2013050548","article-title":"Activity, energy intake, obesity, and the risk of incident kidney stones in postmenopausal women: A report from the Women\u2019s Health Initiative","volume":"25","author":"Sorensen","year":"2014","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.juro.2014.09.010","article-title":"Physical activity, energy intake and the risk of incident kidney stones","volume":"193","author":"Ferraro","year":"2015","journal-title":"J. Urol."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1093\/eurpub\/ckaa162","article-title":"Association between physical activity and kidney stones based on dose-response analyses using restricted cubic splines","volume":"30","author":"Feng","year":"2020","journal-title":"Eur. J. Public Health"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1007\/s10654-018-0426-4","article-title":"Body fatness, diabetes, physical activity and risk of kidney stones: A systematic review and meta-analysis of cohort studies","volume":"33","author":"Aune","year":"2018","journal-title":"Eur. J. Epidemiol."},{"key":"ref_95","doi-asserted-by":"crossref","unstructured":"Stamatelou, K., and Goldfarb, D.S. (2023). Epidemiology of Kidney Stones. Healthcare, 11.","DOI":"10.3390\/healthcare11030424"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"16008","DOI":"10.1038\/nrdp.2016.8","article-title":"Kidney stones","volume":"2","author":"Khan","year":"2016","journal-title":"Nat. Rev. Dis. Primers."},{"key":"ref_97","first-page":"e22119","article-title":"Body Mass Index (BMI): A Screening Tool Analysis","volume":"14","author":"Khanna","year":"2022","journal-title":"Cureus"},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1002\/osp4.474","article-title":"Body mass index and risk of obesity-related conditions in a cohort of 2.9 million people: Evidence from a UK primary care database","volume":"7","author":"Haase","year":"2021","journal-title":"Obes. Sci. Pract."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1016\/S2213-8587(18)30288-2","article-title":"Association of BMI with overall and cause-specific mortality: A population-based cohort study of 3\u00b76 million adults in the UK","volume":"6","author":"Bhaskaran","year":"2018","journal-title":"Lancet Diabetes Endocrinol."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1053\/j.ackd.2008.10.003","article-title":"Obesity and urolithiasis","volume":"16","author":"Asplin","year":"2009","journal-title":"Adv. Chronic Kidney Dis."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s00240-009-0194-4","article-title":"Association of body mass index and urine pH in patients with urolithiasis","volume":"37","author":"Li","year":"2009","journal-title":"Urol. Res."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/j.urology.2009.09.024","article-title":"Relationship between body mass index and quantitative 24-hour urine chemistries in patients with nephrolithiasis","volume":"75","author":"Eisner","year":"2010","journal-title":"Urology"},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"393","DOI":"10.23736\/S0393-2249.18.03113-2","article-title":"Obesity and kidney stone disease: A systematic review","volume":"70","author":"Carbone","year":"2018","journal-title":"Minerva Urol. Nefrol."},{"key":"ref_104","first-page":"63","article-title":"Obesity and the Risk of Developing Kidney Stones: A Systematic Review and Meta-analysis","volume":"1","author":"Emami","year":"2023","journal-title":"Iran. J. Kidney Dis."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1590\/s1677-5538.ibju.2022.0587","article-title":"Impact of body mass index on size and composition of urinary stones: A systematic review and meta-analysis","volume":"49","author":"Wang","year":"2023","journal-title":"Int. Braz. J. Urol."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"100262","DOI":"10.1016\/j.obmed.2020.100262","article-title":"The association of body mass index and quantitative 24 h urine metabolites in patients with Nephrolithiasis: A systematic review and dose response meta analysis","volume":"20","author":"Taheri","year":"2020","journal-title":"Obes. Med."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1093\/ndt\/gfu350","article-title":"Effect of being overweight on urinary metabolic risk factors for kidney stone formation","volume":"30","author":"Shavit","year":"2015","journal-title":"Nephrol. Dial. Transplant."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/j.1523-1755.2004.00386.x","article-title":"The metabolic syndrome and uric acid nephrolithiasis: Novel features of renal manifestation of insulin resistance","volume":"65","author":"Abate","year":"2004","journal-title":"Kidney Int."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s00240-015-0773-5","article-title":"Diabetes mellitus and the risk of urolithiasis: A meta-analysis of observational studies","volume":"43","author":"Liu","year":"2015","journal-title":"Urolithiasis"},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1089\/end.2015.0567","article-title":"Metabolic Syndrome and Kidney Stone Disease: A Systematic Review of Literature","volume":"30","author":"Wong","year":"2016","journal-title":"J. Endourol."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"107843","DOI":"10.1016\/j.diabres.2019.107843","article-title":"Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9","volume":"157","author":"Saeedi","year":"2019","journal-title":"Diabetes Res. Clin. Pract."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/s11906-018-0812-z","article-title":"The Global Epidemic of the Metabolic Syndrome","volume":"20","author":"Saklayen","year":"2018","journal-title":"Curr. Hypertens. Rep."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1007\/s00345-017-2008-6","article-title":"Epidemiology of stone disease across the world","volume":"35","author":"Sorokin","year":"2017","journal-title":"World J. Urol."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1161\/01.CIR.0000111245.75752.C6","article-title":"Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute\/American Heart Association conference on scientific issues related to definition","volume":"109","author":"Grundy","year":"2004","journal-title":"Circulation"},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1681\/ASN.2006030262","article-title":"Type 2 diabetes increases the risk for uric acid stones","volume":"17","author":"Daudon","year":"2006","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"174","DOI":"10.4103\/ajm.ajm_53_20","article-title":"Pathophysiology of diabetes: An overview","volume":"10","author":"Banday","year":"2020","journal-title":"Avicenna J. Med."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/s41574-022-00690-7","article-title":"The burden and risks of emerging complications of diabetes mellitus","volume":"18","author":"Tomic","year":"2022","journal-title":"Nat. Rev. Endocrinol."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1097\/MNH.0000000000000515","article-title":"Urinary oxalate as a potential mediator of kidney disease in diabetes mellitus and obesity","volume":"28","author":"Efe","year":"2019","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"e032094","DOI":"10.1136\/bmjopen-2019-032094","article-title":"Does chronic hyperglycaemia increase the risk of kidney stone disease? results from a systematic review and meta-analysis","volume":"10","author":"Geraghty","year":"2020","journal-title":"BMJ Open."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"104","DOI":"10.12688\/f1000research.28346.1","article-title":"Association between metabolic syndrome components and the risk of developing nephrolithiasis: A systematic review and bayesian meta-analysis","volume":"10","author":"Rahman","year":"2021","journal-title":"F1000Research"},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.ymgme.2021.08.010","article-title":"Assessing causal associations of obesity and diabetes with kidney stones using Mendelian randomization analysis","volume":"134","author":"Yuan","year":"2021","journal-title":"Mol. Genet. Metab."},{"key":"ref_122","first-page":"117","article-title":"Metabolic Syndrome and Nephrolithiasis Risk: Should the Medical Management of Nephrolithiasis Include the Treatment of Metabolic Syndrome?","volume":"17","author":"DiBianco","year":"2015","journal-title":"Rev. Urol."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1016\/j.juro.2013.05.016","article-title":"Effects of visceral fat area and other metabolic parameters on stone composition in patients undergoing percutaneous nephrolithotomy","volume":"190","author":"Zhou","year":"2013","journal-title":"J. Urol."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1111\/iju.12691","article-title":"Weight loss intervention reduces the risk of kidney stone formation in a rat model of metabolic syndrome","volume":"22","author":"Sasaki","year":"2015","journal-title":"Int. J. Urol."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1111\/iju.13957","article-title":"The Urological Association of Asia clinical guideline for urinary stone disease","volume":"26","author":"Taguchi","year":"2019","journal-title":"Int. J. Urol."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1038\/oby.2004.14","article-title":"The role of overweight and obesity in calcium oxalate stone formation","volume":"12","author":"Siener","year":"2004","journal-title":"Obes. Res."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s00240-018-1038-x","article-title":"Current opinions on nephrolithiasis associated with primary hyperparathyroidism","volume":"46","author":"Cong","year":"2018","journal-title":"Urolithiasis."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"908","DOI":"10.2214\/AJR.07.3160","article-title":"Primary hyperparathyroidism: Is there an increased prevalence of renal stone disease?","volume":"191","author":"Suh","year":"2008","journal-title":"AJR Am. J. Roentgenol."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"256","DOI":"10.5114\/reum\/170705","article-title":"Primary hyperparathyroidism: Clinical manifestations, diagnosis and evaluation according to the Fifth International Workshop guidelines","volume":"61","author":"Kochman","year":"2023","journal-title":"Reumatologia."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1210\/jc.2011-0569","article-title":"Nephrolithiasis and renal calcifications in primary hyperparathyroidism","volume":"96","author":"Rejnmark","year":"2011","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1001\/jama.2020.0538","article-title":"Diagnosis and Management of Primary Hyperparathyroidism","volume":"323","author":"Zhu","year":"2020","journal-title":"JAMA"},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"3993","DOI":"10.1210\/jc.2018-01225","article-title":"Primary Hyperparathyroidism","volume":"103","author":"Bilezikian","year":"2018","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1080\/07435800.2018.1431275","article-title":"Occult urolithiasis in asymptomatic primary hyperparathyroidism","volume":"43","author":"Tay","year":"2018","journal-title":"Endocr. Res."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1001\/jamasurg.2017.1721","article-title":"Indications for Surgical Management of Hyperparathyroidism: A Review","volume":"152","author":"Stephen","year":"2017","journal-title":"JAMA Surg."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1089\/end.2012.0406","article-title":"Remote monitoring and supervision of urology residents utilizing integrated endourology suites-a prospective study of patients\u2019 opinions","volume":"27","author":"Anderson","year":"2013","journal-title":"J. Endourol."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1002\/jbmr.4677","article-title":"Evaluation and Management of Primary Hyperparathyroidism: Summary Statement and Guidelines from the Fifth International Workshop","volume":"37","author":"Bilezikian","year":"2022","journal-title":"J. Bone Miner. Res."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.surg.2016.06.062","article-title":"Parathyroidectomy for asymptomatic primary hyperparathyroidism: A revised cost-effectiveness analysis incorporating fracture risk reduction","volume":"161","author":"Zanocco","year":"2017","journal-title":"Surgery"},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1136\/bmj.325.7368.807","article-title":"Risk of renal stone events in primary hyperparathyroidism before and after parathyroid surgery: Controlled retrospective follow up study","volume":"325","author":"Mollerup","year":"2002","journal-title":"BMJ"},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1002\/jbmr.3177","article-title":"Effect of Surgery Versus Observation: Skeletal 5-Year Outcomes in a Randomized Trial of Patients With Primary HPT (the SIPH Study)","volume":"32","author":"Lundstam","year":"2017","journal-title":"J. Bone Miner. Res."},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"R39","DOI":"10.1530\/EJE-16-0430","article-title":"Mechanisms in Endocrinology: Kidney involvement in patients with primary hyperparathyroidism: An update on clinical and molecular aspects","volume":"176","author":"Verdelli","year":"2017","journal-title":"Eur. J. Endocrinol."}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/16\/12\/1932\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:00:46Z","timestamp":1760108446000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/16\/12\/1932"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,18]]},"references-count":140,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,6]]}},"alternative-id":["nu16121932"],"URL":"https:\/\/doi.org\/10.3390\/nu16121932","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,18]]}}}