{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:16:53Z","timestamp":1760145413548,"version":"build-2065373602"},"reference-count":52,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T00:00:00Z","timestamp":1721779200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Coordination for the Improvement of Higher Education Personnel","award":["001"],"award-info":[{"award-number":["001"]}]},{"name":"National Council for Scientific and Technological Development","award":["001"],"award-info":[{"award-number":["001"]}]},{"name":"Piau\u00ed Research Support Foundation","award":["001"],"award-info":[{"award-number":["001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>(1) Background: We examined the effect of the acute administration of olive oil (EVOO), linseed oil (GLO), soybean oil (SO), and palm oil (PO) on gastric motility and appetite in rats. (2) Methods: We assessed food intake, gastric retention (GR), and gene expression in all groups. (3) Results: Both EVOO and GLO were found to enhance the rate of stomach retention, leading to a decrease in hunger. On the other hand, the reduction in food intake caused by SO was accompanied by delayed effects on stomach retention. PO caused an alteration in the mRNA expression of NPY, POMC, and CART. Although PO increased stomach retention after 180 min, it did not affect food intake. It was subsequently verified that the absence of an autonomic reaction did not nullify the influence of EVOO in reducing food consumption. Moreover, in the absence of parasympathetic responses, animals that received PO exhibited a significant decrease in food consumption, probably mediated by lower NPY expression. (4) Conclusions: This study discovered that different oils induce various effects on parameters related to food consumption. Specifically, EVOO reduces food consumption primarily through its impact on the gastrointestinal tract, making it a recommended adjunct for weight loss. Conversely, the intake of PO limits food consumption in the absence of an autonomic reaction, but it is not advised due to its contribution to the development of cardiometabolic disorders.<\/jats:p>","DOI":"10.3390\/nu16152397","type":"journal-article","created":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T08:47:17Z","timestamp":1721810837000},"page":"2397","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Brain Perception of Different Oils on Appetite Regulation: An Anorectic Gene Expression Pattern in the Hypothalamus Dependent on the Vagus Nerve"],"prefix":"10.3390","volume":"16","author":[{"given":"Gele de Carvalho Ara\u00fajo","family":"Lopes","sequence":"first","affiliation":[{"name":"Metabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina 64049-550, PI, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brenda Caroline Rodrigues","family":"Miranda","sequence":"additional","affiliation":[{"name":"Metabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina 64049-550, PI, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Orlando Piauilino Ferreira","family":"Lima","sequence":"additional","affiliation":[{"name":"Metabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina 64049-550, PI, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorddam Almondes","family":"Martins","sequence":"additional","affiliation":[{"name":"Metabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina 64049-550, PI, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1106-4320","authenticated-orcid":false,"given":"Athanara Alves","family":"de Sousa","sequence":"additional","affiliation":[{"name":"Metabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina 64049-550, PI, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9090-4625","authenticated-orcid":false,"given":"Taline 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Federal University of Piau\u00ed, Teresina 64049-550, PI, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucillia Rabelo de Oliveira","family":"Torres","sequence":"additional","affiliation":[{"name":"Federal Institute of Education, Science and Technology of Maranh\u00e3o, Caxias 65030-005, MA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7954-5630","authenticated-orcid":false,"given":"Dennys Esper","family":"Cintra","sequence":"additional","affiliation":[{"name":"Laboratory of Nutritional Genomics, University of Campinas, Campinas 13083-855, SP, Brazil"},{"name":"Nutrigenomics and Lipids Research Center, CELN, School of Applied Sciences University of Campinas, S\u00e3o Paulo 13083-970, SP, Brazil"},{"name":"Hospital Israelita Albert Einstein (HIAE), S\u00e3o Paulo 05652-900, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0598-5529","authenticated-orcid":false,"given":"Ana Maria","family":"Lottenberg","sequence":"additional","affiliation":[{"name":"Nutrigenomics and Lipids Research Center, CELN, School of Applied Sciences University of Campinas, S\u00e3o Paulo 13083-970, SP, Brazil"},{"name":"Hospital Israelita Albert Einstein (HIAE), S\u00e3o Paulo 05652-900, SP, Brazil"},{"name":"Laborat\u00f3rio de L\u00edpides (LIM10), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, University of S\u00e3o Paulo, S\u00e3o Paulo 17012-900, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00edlia","family":"Seelaender","sequence":"additional","affiliation":[{"name":"Cancer Metabolism Research Group, Department of Surgery and LIM26-HCFMUSP, Faculty of Medicine, University of S\u00e3o Paulo, S\u00e3o Paulo 17012-900, SP, 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