{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T01:49:30Z","timestamp":1791510570013,"version":"4.3.4"},"reference-count":64,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2024,8,4]],"date-time":"2024-08-04T00:00:00Z","timestamp":1722729600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Bulgarian National Science Fund","award":["K\u03a0-06-M43\/3\/2020"],"award-info":[{"award-number":["K\u03a0-06-M43\/3\/2020"]}]},{"name":"Bulgarian National Science Fund","award":["BG-RRP-2.004-0008"],"award-info":[{"award-number":["BG-RRP-2.004-0008"]}]},{"name":"European Union-NextGenerationEU","award":["K\u03a0-06-M43\/3\/2020"],"award-info":[{"award-number":["K\u03a0-06-M43\/3\/2020"]}]},{"name":"European Union-NextGenerationEU","award":["BG-RRP-2.004-0008"],"award-info":[{"award-number":["BG-RRP-2.004-0008"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: The prevalence of sarcopenic obesity among adults aged \u226565 years is increasing worldwide. It is a condition that describes the concomitant presence of sarcopenia and obesity, but it appears to be associated with greater increases in the risks for disability, morbidity, and mortality than the two conditions combined. The current review aims to summarize the available literature data on the effectiveness of lifestyle modification for the management of this high-risk geriatric syndrome. Methods: We conducted a comprehensive search across multiple databases, including PubMed, Scopus, Web of Science, and Cochrane Library, for publications published from January 1950 to June 2024. Results: The detection of early preventive and therapeutic approaches to combat sarcopenic obesity is essential for healthy aging. There is ample evidence that suggests that poor dietary habits and physical inactivity are the main reasons for the development of sarcopenic obesity and should thus be the main targets for intervention. In the absence of effective pharmacological interventions, the best effect on sarcopenic obesity is achieved by combination with proper dietary intervention and regular physical activity according to the individual\u2019s health condition. Conclusions. Further research is needed to discover the most effective strategy for the prevention and treatment of sarcopenic obesity, as well as potential pharmacological options to improve muscle mass and function in older populations with physical restrictions.<\/jats:p>","DOI":"10.3390\/nu16152560","type":"journal-article","created":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T11:28:54Z","timestamp":1722857334000},"page":"2560","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Nutritional Management and Physical Activity in the Treatment of Sarcopenic Obesity: A Review of the Literature"],"prefix":"10.3390","volume":"16","author":[{"given":"Yavor","family":"Assyov","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Clinic of Endocrinology, University Hospital \u201cAlexandrovska\u201d Medical University, Georgi Sofiyski 1 Str., 1431 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iveta","family":"Nedeva","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Hygiene, Medical University of Sofia, 1431 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Borian","family":"Spassov","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging, Medical University, 1431 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonina","family":"Gerganova","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Clinic of Endocrinology, University Hospital \u201cAlexandrovska\u201d Medical University, Georgi Sofiyski 1 Str., 1431 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toni","family":"Velikov","sequence":"additional","affiliation":[{"name":"Clinic of Cardiology, SHATC \u201cMedica Cor\u201d EAD, 7000 Rousse, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4829-9449","authenticated-orcid":false,"given":"Zdravko","family":"Kamenov","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Clinic of Endocrinology, University Hospital \u201cAlexandrovska\u201d Medical University, Georgi Sofiyski 1 Str., 1431 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0593-1272","authenticated-orcid":false,"given":"Tsvetelina","family":"Velikova","sequence":"additional","affiliation":[{"name":"Medical Faculty, Sofia University St. Kliment Ohridski, 1407 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/s00198-009-1059-y","article-title":"Sarcopenia: Etiology, clinical consequences, intervention, and assessment","volume":"21","author":"Lang","year":"2010","journal-title":"Osteoporos. 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