{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T13:51:22Z","timestamp":1785333082763,"version":"3.55.0"},"reference-count":45,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2024,10,9]],"date-time":"2024-10-09T00:00:00Z","timestamp":1728432000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background\/objectives: The connection between diet and migraine has gained increasing attention in migraine research due to its potential relevance as part of migraine treatment. This study reviewed the current evidence on the use of diets or specific foods in the prevention of migraine. Methods: A PubMed search was performed with the keywords \u201cdiet and migraine\u201d OR \u201cbrain-gut-axis and migraine\u201d. One author (KVN) screened titles, abstracts, and full-text articles and excluded or included them based on eligibility criteria. Results: A ketogenic diet and a \u201cDietary Approaches to Stop Hypertension\u201d diet reduced attack duration (p &lt; 0.002), frequency (p &lt; 0.05), and severity (p &lt; 0.01). The ketogenic diet also reduced monthly medication intake (p \u2264 0.05). A low-fat vegan diet mixed with an elimination diet reduced the attack duration (p &lt; 0.01), frequency (p &lt; 0.05), severity (p &lt; 0.0001), and percentage of medicated headaches (p &lt; 0.001). Elimination diet reduced attack duration (p &lt; 0.05), frequency (p &lt; 0.02), severity (p &lt; 0.01), and medication intake (p &lt; 0.002). Elimination diet with IgG-positive foods reduced attack frequency (p &lt; 0.001), and total medication intake (p &lt; 0.01). Gluten-free diet reduced frequency (p = 0.02) and severity (p = 0.013). Conclusions: Certain diets and food items may trigger attacks in some migraine patients, though the overall evidence supporting this is limited. Modifying a diet may reduce symptoms such as attack duration, frequency, severity, and medication intake. However, the included studies\u2019 small populations and diverse study designs make the results difficult to apply in clinical practise. Further high-quality, double-blinded, randomised controlled trials are necessary to confirm the association between diet and migraine.<\/jats:p>","DOI":"10.3390\/nu16193415","type":"journal-article","created":{"date-parts":[[2024,10,9]],"date-time":"2024-10-09T07:39:52Z","timestamp":1728459592000},"page":"3415","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["The Evidence for Diet as a Treatment in Migraine\u2014A Review"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3355-4890","authenticated-orcid":false,"given":"Kattia Valentine","family":"Nguyen","sequence":"first","affiliation":[{"name":"Danish Headache Center, Department of Neurology, Copenhagen University Hospital\u2014Rigshospitalet-Glostrup, 2600 Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6262-2986","authenticated-orcid":false,"given":"Henrik Winther","family":"Schytz","sequence":"additional","affiliation":[{"name":"Danish Headache Center, Department of Neurology, Copenhagen University Hospital\u2014Rigshospitalet-Glostrup, 2600 Copenhagen, Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Headache Classification Committee of the International Headache Society (IHS) (2018). 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