{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T16:15:53Z","timestamp":1792426553748,"version":"4.5.0"},"reference-count":105,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T00:00:00Z","timestamp":1730332800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melina Gates Foundation","doi-asserted-by":"publisher","award":["INV-058017"],"award-info":[{"award-number":["INV-058017"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background\/Objectives: Despite advances in maternal nutritional knowledge, the effect of maternal diet, micronutrient status and undernutrition, and the effect of maternal supplementation on fetal, neonatal and infant outcomes still have gaps in the literature. This overview of reviews is intended to assess the available information on these issues and identify the main maternal nutritional factors associated with offspring outcomes in low- and middle-income countries as possible targets for public health interventions. Methods: The literature search was performed in Medline (PubMed) and Cochrane Library datasets in June 2024. Pre-specified outcomes in offspring were pooled using standard meta-analytical methods. Results: We found consistent evidence on the impact of maternal undernutrition indicated by low body mass index (BMI), mid-upper arm circumference (MUAC), and stature, but not of individual micronutrient status, on intrauterine-growth retardation, preterm birth, low birth weight, and small for gestational age, with research showing a possible effect of maternal undernutrition in later child nutritional status. Studies on micronutrient supplementation showed possible beneficial effects of iron, vitamin D, and multiple micronutrients on birthweight and\/or decreasing small for gestational age, as well as a possible effect of calcium on preterm birth reduction. Interventions showing more consistent beneficial outcomes were balanced protein-energy and lipid base supplements, which demonstrated improved weight in newborns from supplemented mothers and a decreased risk of adverse neonatal outcomes. Conclusions: Further research is needed to identify the benefits and risks of maternal individual micronutrient supplementation on neonatal and further child outcomes.<\/jats:p>","DOI":"10.3390\/nu16213725","type":"journal-article","created":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T09:57:36Z","timestamp":1730368656000},"page":"3725","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Associations of Maternal Nutritional Status and Supplementation with Fetal, Newborn, and Infant Outcomes in Low-Income and Middle-Income Settings: An Overview of Reviews"],"prefix":"10.3390","volume":"16","author":[{"given":"Doris","family":"Gonz\u00e1lez-Fern\u00e1ndez","sequence":"first","affiliation":[{"name":"Centre for Global Child Health, Hospital for Sick Children, Toronto, ON M5G 0A4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5214-6103","authenticated-orcid":false,"given":"Oviya","family":"Muralidharan","sequence":"additional","affiliation":[{"name":"Centre for Global Child Health, Hospital for Sick Children, Toronto, ON M5G 0A4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1200-4725","authenticated-orcid":false,"given":"Paulo","family":"Neves","sequence":"additional","affiliation":[{"name":"Centre for Global Child Health, Hospital for Sick Children, Toronto, ON M5G 0A4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0637-599X","authenticated-orcid":false,"given":"Zulfiqar","family":"Bhutta","sequence":"additional","affiliation":[{"name":"Centre for Global Child Health, Hospital for Sick Children, Toronto, ON M5G 0A4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,31]]},"reference":[{"key":"ref_1","unstructured":"WHO (2024, June 10). Low Birth Weight. Nutrition Landscape Information System (NLiS): World Health Organization. Available online: https:\/\/www.who.int\/data\/nutrition\/nlis\/info\/low-birth-weight."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1016\/S0140-6736(21)00394-9","article-title":"Revisiting maternal and child undernutrition in low-income and middle-income countries: Variable progress towards an unfinished agenda","volume":"397","author":"Victora","year":"2021","journal-title":"Lancet"},{"key":"ref_3","unstructured":"UNICEF (2024, October 18). The State of Food Security and Nutrition in the World 2024: Financing to End Hunger, Food Insecurity and Malnutrition in All Its Forms. Available online: http:\/\/icsfarchives.net\/20253\/."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"e2023064167","DOI":"10.1542\/peds.2023-064167","article-title":"The Global Burden of Disease Attributable to Child and Maternal Malnutrition: 1990\u20132019","volume":"154","author":"Gong","year":"2024","journal-title":"Pediatrics"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/S0140-6736(19)32540-1","article-title":"A future for the world\u2019s children? A WHO-UNICEF-Lancet Commission","volume":"395","author":"Clark","year":"2020","journal-title":"Lancet"},{"key":"ref_6","unstructured":"World Health Organization (2023). Levels and Trends in Child Malnutrition UNICEF\/WHO\/World Bank Group Joint Child Malnutrition Estimates Key Findings of the 2023 Edition, World Health Organization."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Gaccioli, F., and Lager, S. (2016). Placental nutrient transport and intrauterine growth restriction. Front. Physiol., 7.","DOI":"10.3389\/fphys.2016.00040"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1001\/jamapediatrics.2020.1097","article-title":"Association of Intrauterine Growth Restriction and Small for Gestational Age Status with Childhood Cognitive Outcomes: A Systematic Review and Meta-analysis","volume":"174","author":"Sacchi","year":"2020","journal-title":"JAMA Pediatr."},{"key":"ref_9","unstructured":"WHO (2024, June 10). Preterm Birth. Fact Sheets: World Health Organization. Available online: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/preterm-birth."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"F225","DOI":"10.1136\/adc.2009.161117","article-title":"A structured review of the recent literature on the economic consequences of preterm birth","volume":"96","author":"Petrou","year":"2011","journal-title":"Arch. Dis. Child. Fetal Neonatal Ed."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"S107","DOI":"10.1111\/j.1523-1755.2005.09718.x","article-title":"Long-term consequences of low birth weight","volume":"68","author":"Reyes","year":"2005","journal-title":"Kidney Int. Suppl."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s11906-019-0969-0","article-title":"Low Birth Weight, Blood Pressure and Renal Susceptibility","volume":"21","author":"Coats","year":"2019","journal-title":"Curr. Hypertens. Rep."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1017\/S2040174415001439","article-title":"Review of the importance of nutrition during the first 1000 days: Maternal nutritional status and its associations with fetal growth and birth, neonatal and infant outcomes among African women","volume":"7","author":"Wrottesley","year":"2016","journal-title":"J. Dev. Orig. Health Dis."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"111565","DOI":"10.1016\/j.nut.2021.111565","article-title":"Determinants of malnutrition among children: A systematic review","volume":"96","author":"Katoch","year":"2022","journal-title":"Nutrition"},{"key":"ref_15","unstructured":"Shekar, M., Heaver, R., and Lee, Y.-K. (2006). Repositioning Nutrition as Central to Development: A Strategy for Large Scale Action, World Bank Publications."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1038\/s41586-023-06501-x","article-title":"Causes and consequences of child growth faltering in low-resource settings","volume":"621","author":"Mertens","year":"2023","journal-title":"Nature"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1136\/bmj.328.7443.816","article-title":"Maternal and child health: Is South Asia ready for change?","volume":"328","author":"Bhutta","year":"2004","journal-title":"BMJ"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Goossen, K., Hess, S., Lunny, C., and Pieper, D. (2020). Database combinations to retrieve systematic reviews in overviews of reviews: A methodological study. BMC Med. Res. Methodol., 20.","DOI":"10.1186\/s12874-020-00983-3"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/hir.12276","article-title":"Meeting the review family: Exploring review types and associated information retrieval requirements","volume":"36","author":"Sutton","year":"2019","journal-title":"Health Inf. Libr. J."},{"key":"ref_20","unstructured":"Roser, M., Arriagada, P., Hasell, J., Ritchie, H., and Ortiz-Ospina, E. (2024, June 10). Data Page: World Bank Income Groups. \u201cEconomic Growth\u201d 2023. Available online: https:\/\/ourworldindata.org\/grapher\/world-bank-income-groups."},{"key":"ref_21","unstructured":"Pollock, M., Fernandes, R.M., Becker, L.A., Pieper, D., and Hartling, L. (2020). Chapter V: Overviews of reviews. Cochrane Handbook for Systematic Reviews of Interventions Version, Cochrane."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"j4008","DOI":"10.1136\/bmj.j4008","article-title":"AMSTAR 2: A critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both","volume":"358","author":"Shea","year":"2017","journal-title":"BMJ"},{"key":"ref_23","first-page":"Cd000230","article-title":"Zinc supplementation for improving pregnancy and infant outcome","volume":"3","author":"Carducci","year":"2021","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_24","first-page":"Cd007079","article-title":"Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes","volume":"2015","author":"Buppasiri","year":"2015","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_25","first-page":"Cd012610","article-title":"Lipid-based nutrient supplements for maternal, birth, and infant developmental outcomes","volume":"8","author":"Das","year":"2018","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_26","first-page":"Cd001059","article-title":"Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems","volume":"10","author":"Hofmeyr","year":"2018","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_27","first-page":"Cd008666","article-title":"Vitamin A supplementation during pregnancy for maternal and newborn outcomes","volume":"2015","author":"McCauley","year":"2015","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_28","first-page":"Cd005944","article-title":"Vitamin A supplementation for postpartum women","volume":"3","author":"Oliveira","year":"2016","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Ota, E., Hori, H., Mori, R., Tobe-Gai, R., and Farrar, D. (2015). Antenatal dietary education and supplementation to increase energy and protein intake. Cochrane Database Syst. Rev., Cd000032.","DOI":"10.1002\/14651858.CD000032.pub3"},{"key":"ref_30","first-page":"Cd004736","article-title":"Daily oral iron supplementation during pregnancy","volume":"2015","author":"Dowswell","year":"2015","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_31","first-page":"Cd004069","article-title":"Vitamin E supplementation in pregnancy","volume":"2015","author":"Rumbold","year":"2015","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Rumbold, A., Ota, E., Nagata, C., Shahrook, S., and Crowther, C.A. (2015). Vitamin C supplementation in pregnancy. Cochrane Database Syst. Rev., Cd004072.","DOI":"10.1002\/14651858.CD004072.pub3"},{"key":"ref_33","first-page":"Cd004073","article-title":"Vitamin supplementation for preventing miscarriage","volume":"2016","author":"Balogun","year":"2016","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_34","first-page":"Cd004905","article-title":"Multiple-micronutrient supplementation for women during pregnancy","volume":"4","author":"Haider","year":"2017","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_35","first-page":"Cd008873","article-title":"Vitamin D supplementation for women during pregnancy","volume":"7","author":"Palacios","year":"2019","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Akombi, B.J., Agho, K.E., Hall, J.J., Wali, N., Renzaho, A.M.N., and Merom, D. (2017). Stunting, Wasting and Underweight in Sub-Saharan Africa: A Systematic Review. Int. J. Environ. Res. Public Health, 14.","DOI":"10.3390\/ijerph14080863"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1694s","DOI":"10.3945\/ajcn.117.156075","article-title":"U-shaped curve for risk associated with maternal hemoglobin, iron status, or iron supplementation","volume":"106","author":"Dewey","year":"2017","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"100082","DOI":"10.1016\/j.advnut.2023.06.005","article-title":"Human Milk Micronutrients and Child Growth and Body Composition in the First 2 years: A Systematic Review","volume":"15","author":"Reyes","year":"2024","journal-title":"Adv. Nutr."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1111\/nyas.14121","article-title":"Review of the evidence regarding the use of antenatal multiple micronutrient supplementation in low- and middle-income countries","volume":"1444","author":"Bourassa","year":"2019","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"e12960","DOI":"10.1111\/mcn.12960","article-title":"Impact of nutrient supplementation on maternal nutrition and child growth and development in Sub-Saharan Africa: The case of small-quantity lipid-based nutrient supplements","volume":"16","year":"2020","journal-title":"Matern. Child Nutr."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"100094","DOI":"10.1016\/j.cdnut.2023.100094","article-title":"Nutritious Supplemental Foods for Pregnant Women from Food Insecure Settings: Types, Nutritional Composition, and Relationships to Health Outcomes","volume":"7","author":"Ciulei","year":"2023","journal-title":"Curr. Dev. Nutr."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1111\/ppe.12433","article-title":"What Do We Know about Risk Factors for Fetal Growth Restriction in Africa at the Time of Sustainable Development Goals? A Scoping Review","volume":"32","author":"Accrombessi","year":"2018","journal-title":"Paediatr. Perinat. Epidemiol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.biochi.2015.12.003","article-title":"Early pregnancy B vitamin status, one carbon metabolism, pregnancy outcome and child development","volume":"126","author":"Murphy","year":"2016","journal-title":"Biochimie"},{"key":"ref_44","first-page":"Cd010647","article-title":"Supplementation with multiple micronutrients for breastfeeding women for improving outcomes for the mother and baby","volume":"2","author":"Abe","year":"2016","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1093\/advances\/nmaa156","article-title":"Associations between Maternal Dietary Patterns and Perinatal Outcomes: A Systematic Review and Meta-Analysis of Cohort Studies","volume":"12","author":"Abdollahi","year":"2021","journal-title":"Adv. Nutr."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"3706","DOI":"10.1002\/fsn3.3388","article-title":"Inadequate dietary diversity during pregnancy increases the risk of maternal anemia and low birth weight in Africa: A systematic review and meta-analysis","volume":"11","author":"Seid","year":"2023","journal-title":"Food Sci. Nutr."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1186\/1742-4755-11-S3-S3","article-title":"Preconception care: Nutritional risks and interventions","volume":"11","author":"Dean","year":"2014","journal-title":"Reprod. Health"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1111\/obr.12293","article-title":"Maternal body mass index and risk of birth and maternal health outcomes in low- and middle-income countries: A systematic review and meta-analysis","volume":"16","author":"Rahman","year":"2015","journal-title":"Obes. Rev."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Asefa, F., Cummins, A., Dessie, Y., Hayen, A., and Foureur, M. (2020). Gestational weight gain and its effect on birth outcomes in sub-Saharan Africa: Systematic review and meta-analysis. PLoS ONE, 15.","DOI":"10.1371\/journal.pone.0231889"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1007\/s43032-021-00756-3","article-title":"Maternal Factors for Intrauterine Growth Retardation: Systematic Review and Meta-Analysis of Observational Studies","volume":"30","author":"Yang","year":"2023","journal-title":"Reprod. Sci."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.ejogrb.2016.05.042","article-title":"Maternal anthropometry to predict small for gestational age: A meta-analysis","volume":"203","author":"Goto","year":"2016","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1111\/ppe.12855","article-title":"Preconception exposures and adverse pregnancy, birth and postpartum outcomes: Umbrella review of systematic reviews","volume":"36","author":"Daly","year":"2022","journal-title":"Paediatr. Perinat. Epidemiol."},{"key":"ref_53","first-page":"Cd007950","article-title":"Effects and safety of periconceptional oral folate supplementation for preventing birth defects","volume":"2015","year":"2015","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1038\/ijo.2010.162","article-title":"Relationships between pregnancy outcomes, biochemical markers and pre-pregnancy body mass index","volume":"35","author":"Han","year":"2011","journal-title":"Int. J. Obes."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"899","DOI":"10.2147\/IJWH.S67130","article-title":"Associations of consumption of fruits and vegetables during pregnancy with infant birth weight or small for gestational age births: A systematic review of the literature","volume":"6","author":"Murphy","year":"2014","journal-title":"Int. J. Womens Health"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"281","DOI":"10.26719\/2011.17.4.281","article-title":"Relationship between maternal characteristics and neonatal birth size in Egypt","volume":"17","author":"Hassan","year":"2011","journal-title":"East. Mediterr. Health J."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1080\/07315724.2008.10719685","article-title":"Maternal nutrition and birth size among urban affluent and rural women in India","volume":"27","author":"Kanade","year":"2008","journal-title":"J. Am. Coll. Nutr."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1093\/jn\/131.4.1217","article-title":"Intake of micronutrient-rich foods in rural Indian mothers is associated with the size of their babies at birth: Pune Maternal Nutrition Study","volume":"131","author":"Rao","year":"2001","journal-title":"J. Nutr."},{"key":"ref_59","first-page":"125","article-title":"Maternal Anemia during pregnancy and infant low birth weight: A systematic review and Meta-analysis","volume":"15","author":"Rahmati","year":"2017","journal-title":"Int. J. Reprod. Biomed."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.3945\/ajcn.115.123083","article-title":"Prevalence of vitamin B-12 insufficiency during pregnancy and its effect on offspring birth weight: A systematic review and meta-analysis","volume":"103","author":"Sukumar","year":"2016","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"566","DOI":"10.7326\/M14-2932","article-title":"Routine iron supplementation and screening for iron deficiency anemia in pregnancy: A systematic review for the U.S. Preventive Services Task Force","volume":"162","author":"Cantor","year":"2015","journal-title":"Ann. Intern. Med."},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Amegah, A.K., Klevor, M.K., and Wagner, C.L. (2017). Maternal vitamin D insufficiency and risk of adverse pregnancy and birth outcomes: A systematic review and meta-analysis of longitudinal studies. PLoS ONE, 12.","DOI":"10.1371\/journal.pone.0173605"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"2881","DOI":"10.1007\/s00394-022-02866-3","article-title":"Effect of maternal vitamin D status on risk of adverse birth outcomes: A systematic review and dose-response meta-analysis of observational studies","volume":"61","author":"Zhao","year":"2022","journal-title":"Eur. J. Nutr."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1002\/uog.14910","article-title":"Omega-3 supplementation during pregnancy to prevent recurrent intrauterine growth restriction: Systematic review and meta-analysis of randomized controlled trials","volume":"46","author":"Saccone","year":"2015","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.3945\/ajcn.113.080655","article-title":"Effects of dietary interventions on neonatal and infant outcomes: A systematic review and meta-analysis","volume":"100","author":"Gresham","year":"2014","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"495","DOI":"10.3945\/ajcn.115.107896","article-title":"Maternal anemia and risk of adverse birth and health outcomes in low- and middle-income countries: Systematic review and meta-analysis","volume":"103","author":"Rahman","year":"2016","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/jebm.12344","article-title":"Oral iron-based interventions for prevention of critical outcomes in pregnancy and postnatal care: An overview and update of systematic reviews","volume":"12","author":"Abraha","year":"2019","journal-title":"J. Evid. Based Med."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"2389","DOI":"10.3109\/14767058.2015.1086742","article-title":"Omega-3 long-chain polyunsaturated fatty acids and fish oil supplementation during pregnancy: Which evidence?","volume":"29","author":"Saccone","year":"2016","journal-title":"J. Matern. Fetal Neonatal Med."},{"key":"ref_69","doi-asserted-by":"crossref","unstructured":"Figueiredo, A., Gomes-Filho, I.S., Silva, R.B., Pereira, P.P.S., Mata, F., Lyrio, A.O., Souza, E.S., Cruz, S.S., and Pereira, M.G. (2018). Maternal Anemia and Low Birth Weight: A Systematic Review and Meta-Analysis. Nutrients, 10.","DOI":"10.3390\/nu10050601"},{"key":"ref_70","doi-asserted-by":"crossref","unstructured":"Maghsoudlou, S., Cnattingius, S., Stephansson, O., Aarabi, M., Semnani, S., Montgomery, S.M., and Bahmanyar, S. (2016). Maternal haemoglobin concentrations before and during pregnancy and stillbirth risk: A population-based case-control study. BMC Pregnancy Childbirth, 16.","DOI":"10.1186\/s12884-016-0924-x"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"100021","DOI":"10.1016\/j.puhip.2020.100021","article-title":"Maternal anaemia and risk of adverse obstetric and neonatal outcomes in South Asian countries: A systematic review and meta-analysis","volume":"1","author":"Rahman","year":"2020","journal-title":"Public Health Pract."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.clnesp.2023.01.005","article-title":"Influence of hypovitaminosis D during pregnancy on glycemic and lipid profile, inflammatory indicators and anthropometry of pregnant and newborn","volume":"54","author":"Cardoso","year":"2023","journal-title":"Clin. Nutr. ESPEN"},{"key":"ref_73","first-page":"212","article-title":"Associations of Maternal Vitamin B12 Concentration in Pregnancy with the Risks of Preterm Birth and Low Birth Weight: A Systematic Review and Meta-Analysis of Individual Participant Data","volume":"185","author":"Rogne","year":"2017","journal-title":"Am. J. Epidemiol."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1038\/s41430-020-00733-0","article-title":"Vitamin D during pregnancy and its association with birth outcomes: A Brazilian cohort study","volume":"75","author":"Benaim","year":"2021","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_75","doi-asserted-by":"crossref","unstructured":"van der Pligt, P., Willcox, J., Szymlek-Gay, E.A., Murray, E., Worsley, A., and Daly, R.M. (2018). Associations of Maternal Vitamin D Deficiency with Pregnancy and Neonatal Complications in Developing Countries: A Systematic Review. Nutrients, 10.","DOI":"10.3390\/nu10050640"},{"key":"ref_76","doi-asserted-by":"crossref","unstructured":"Liu, E., Pimpin, L., Shulkin, M., Kranz, S., Duggan, C.P., Mozaffarian, D., and Fawzi, W.W. (2018). Effect of Zinc Supplementation on Growth Outcomes in Children under 5 Years of Age. Nutrients, 10.","DOI":"10.3390\/nu10030377"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1159\/000354941","article-title":"Interventions to address maternal and childhood undernutrition: Current evidence","volume":"78","author":"Bhutta","year":"2014","journal-title":"Nestle Nutr. Inst. Workshop Ser."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1093\/ajcn\/32.2.455","article-title":"Nutritional supplementation and the outcome of pregnancy. I. Birth weight","volume":"32","author":"Mora","year":"1979","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1111\/mcn.12183","article-title":"The effect of balanced protein energy supplementation in undernourished pregnant women and child physical growth in low- and middle-income countries: A systematic review and meta-analysis","volume":"11","author":"Stevens","year":"2015","journal-title":"Matern. Child. Nutr."},{"key":"ref_80","doi-asserted-by":"crossref","unstructured":"Lassi, Z.S., Padhani, Z.A., Rabbani, A., Rind, F., Salam, R.A., Das, J.K., and Bhutta, Z.A. (2020). Impact of Dietary Interventions during Pregnancy on Maternal, Neonatal, and Child Outcomes in Low- and Middle-Income Countries. Nutrients, 12.","DOI":"10.3390\/nu12020531"},{"key":"ref_81","doi-asserted-by":"crossref","unstructured":"Santander Ballest\u00edn, S., Gim\u00e9nez Campos, M.I., Ballestin Ballestin, J., and Luesma Bartolom\u00e9, M.J. (2021). Is supplementation with micronutrients still necessary during pregnancy? A review. Nutrients, 13.","DOI":"10.3390\/nu13093134"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.nutres.2023.04.009","article-title":"Dietary Inflammatory Index during pregnancy is associated with birth weight and child anthropometry up to 10 years old: A systematic review and meta-analysis","volume":"114","author":"Souza","year":"2023","journal-title":"Nutr. Res."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1093\/ajcn\/nqab019","article-title":"Maternal diet patterns during early pregnancy in relation to neonatal outcomes","volume":"114","author":"Yisahak","year":"2021","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1093\/ajcn\/nqab145","article-title":"Healthy dietary patterns and common pregnancy complications: A prospective and longitudinal study","volume":"114","author":"Li","year":"2021","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_85","doi-asserted-by":"crossref","unstructured":"Elmighrabi, N.F., Fleming, C.A., and Agho, K.E. (2023). Wasting and Underweight in Northern African Children: Findings from Multiple-Indicator Cluster Surveys, 2014\u20132018. Nutrients, 15.","DOI":"10.3390\/nu15143207"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"2240158","DOI":"10.1080\/16549716.2023.2240158","article-title":"Childhood undernutrition in North Africa: Systematic review and meta-analysis of observational studies","volume":"16","author":"Elmighrabi","year":"2023","journal-title":"Glob. Health Action."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1002\/ijgo.12289","article-title":"Accuracy of on-site tests to detect anemia during prenatal care","volume":"139","author":"Sobhy","year":"2017","journal-title":"Int. J. Gynaecol. Obstet."},{"key":"ref_88","doi-asserted-by":"crossref","unstructured":"Manger, M.S., Brown, K.H., Osendarp, S.J.M., Atkin, R.A., and McDonald, C.M. (2022). Barriers to and Enablers of the Inclusion of Micronutrient Biomarkers in National Surveys and Surveillance Systems in Low- and Middle-Income Countries. Nutrients, 14.","DOI":"10.3390\/nu14102009"},{"key":"ref_89","doi-asserted-by":"crossref","unstructured":"Gonz\u00e1lez-Fern\u00e1ndez, D., Nemeth, E., Pons, E.d.C., Rueda, D., Sinisterra, O.T., Murillo, E., Sangkhae, V., Starr, L., Scott, M.E., and Koski, K.G. (2024). Multiple Infections, Nutrient Deficiencies, and Inflammation as Determinants of Anemia and Iron Status during Pregnancy: The MINDI Cohort. Nutrients, 16.","DOI":"10.3390\/nu16111748"},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1111\/nyas.14167","article-title":"Reexamination of hemoglobin adjustments to define anemia: Altitude and smoking","volume":"1450","author":"Sharma","year":"2019","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"1620S","DOI":"10.3945\/ajcn.117.155903","article-title":"Emerging understanding and measurement of plasma volume expansion in pregnancy","volume":"106","author":"Vricella","year":"2017","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/uog.17360","article-title":"Physiological adaptation of maternal plasma volume during pregnancy: A systematic review and meta-analysis","volume":"49","author":"Spaanderman","year":"2017","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_93","doi-asserted-by":"crossref","unstructured":"Schr\u00f6der-Heurich, B., Springer, C.J.P., and von Versen-H\u00f6ynck, F. (2020). Vitamin D Effects on the Immune System from Periconception through Pregnancy. Nutrients, 12.","DOI":"10.3390\/nu12051432"},{"key":"ref_94","doi-asserted-by":"crossref","unstructured":"Yang, J., Zhu, L., Li, X., Zheng, H., Wang, Z., Hao, Z., and Liu, Y. (2017). Maternal iodine status during lactation and infant weight and length in Henan Province, China. BMC Pregnancy Childbirth, 17.","DOI":"10.1186\/s12884-017-1569-0"},{"key":"ref_95","doi-asserted-by":"crossref","unstructured":"Gonz\u00e1lez-Fern\u00e1ndez, D., Nemeth, E., Pons, E.d.C., Sinisterra, O.T., Rueda, D., Starr, L., Sangkhae, V., Murillo, E., Scott, M.E., and Koski, K.G. (2022). Multiple indicators of undernutrition, infection, and inflammation in lactating women are associated with maternal iron status and infant anthropometry in Panama: The MINDI cohort. Nutrients, 14.","DOI":"10.3390\/nu14173497"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1038\/s41390-018-0072-2","article-title":"Maternal and infant vitamin B12 status during infancy predict linear growth at 5 years","volume":"84","author":"Strand","year":"2018","journal-title":"Pediatr. Res."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/ejcn.2012.7","article-title":"Calcium intake of rural Gambian infants: A quantitative study of the relative contributions of breast milk and complementary foods at 3 and 12 months of age","volume":"66","author":"Jarjou","year":"2012","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1111\/bjh.14584","article-title":"Safety and benefits of antenatal oral iron supplementation in low-income countries: A review","volume":"177","author":"Mwangi","year":"2017","journal-title":"Br. J. Haematol."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/MCO.0000000000000557","article-title":"Interventions to prevent iron deficiency during the first 1000 days in low-income and middle-income countries: Recent advances and challenges","volume":"22","author":"Lewies","year":"2019","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1093\/biolre\/ioab023","article-title":"Role of zinc in female reproduction","volume":"104","author":"Garner","year":"2021","journal-title":"Biol. Reprod."},{"key":"ref_101","first-page":"38","article-title":"Role of reactive oxygen species in female reproduction and the effects of antioxidant supplementation-Part 2","volume":"16","author":"Agarwal","year":"2005","journal-title":"Agro Food Ind. Hi Tech"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"102217","DOI":"10.1016\/j.cpcardiol.2023.102217","article-title":"Association between calcium supplementation and gestational hypertension, and preeclampsia: A Meta-analysis of 26 randomized controlled trials","volume":"49","author":"Jaiswal","year":"2024","journal-title":"Curr. Probl. Cardiol."},{"key":"ref_103","first-page":"151","article-title":"Prevention of preeclampsia with low-dose aspirin or calcium supplementation","volume":"5","author":"Taherian","year":"2002","journal-title":"Arch. Iran. Med."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"106100","DOI":"10.1016\/j.phrs.2022.106100","article-title":"The effects of omega-3 polyunsaturated fatty acids supplementation in pregnancy, lactation, and infancy: An umbrella review of meta-analyses of randomized trials","volume":"177","author":"Firouzabadi","year":"2022","journal-title":"Pharmacol. Res."},{"key":"ref_105","doi-asserted-by":"crossref","unstructured":"Shenoy, S., Sharma, P., Rao, A., Aparna, N., Adenikinju, D., Iloegbu, C., Pate\u00f1a, J., Vieira, D., Gyamfi, J., and Peprah, E. (2023). Evidence-based interventions to reduce maternal malnutrition in low and middle-income countries: A systematic review. Front. Health Serv., 3.","DOI":"10.3389\/frhs.2023.1155928"}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/16\/21\/3725\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:24:56Z","timestamp":1760113496000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/16\/21\/3725"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,31]]},"references-count":105,"journal-issue":{"issue":"21","published-online":{"date-parts":[[2024,11]]}},"alternative-id":["nu16213725"],"URL":"https:\/\/doi.org\/10.3390\/nu16213725","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,31]]}}}